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Background: Antibody-based immunoassays have enabled quantification of very low concentrations of phosphorylated tau (p-tau) protein forms in cerebrospinal fluid (CSF), aiding in the diagnosis of AD. Mass spectrometry enables absolute quantification of multiple p-tau variants within a single run. The goal of this study was to compare the performance of mass spectrometry assessments of p-tau181, p-
Considerable time is often spent optimizing antennas to meet specific design metrics. Rarely, however, are the resulting antenna designs compared to rigorous physical bounds on those metrics. Here, we study the performance of optimized planar meander line antennas with respect to such bounds. Results show that these simple structures meet the lower bound on the radiation quality factor (Q-factor)
Family reunification is, in the words of the European Union (EU) Family Reunification Directive (2003/86/EC), a ‘necessary way of making family life possible’ and preserving family unity. Yet, barriers exist which hinder refugees’ realisation of their right to family reunification. By taking the plight of Eritrean refugees in Europe as a pertinent case study, this paper shows the obstacles that “p
Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability. After aneurysm rupture, erythrocytes in the subarachnoid space lyse and liberate free hemoglobin (Hb), a key driver for the development of DCI. Hemoglobin i
It is shown that under certain regularity conditions on the norm, the functions in a nontrivial invariant subspace of the backward shift operator have meromorphic pseudocontinuations in the Nevanlinna class of the exterior of the unit disk. In addition, we provide a regularity condition which implies that the subspace itself is contained in the Nevanlinna class of the disc.
Popular Abstract in Swedish Magnetresonanstomografi (MRT) är en metod för framställning av bilder av kroppen och av sjukliga förändringar i kroppen. När metoden introducerades ansågs den utomordentligt goda inbyggda vävnadskontrasten vara tillräcklig för att särskilja olika sjukliga förändringar, speciellt i hjärnan. Det har emellertid visat sig att förmågan att upptäcka sjukliga förändringar är oAims of the study The aims of this study using Gadodiamide injection were to investigate: · Whether Gadodiamide injection was comparable to Gd-DTPA for the enhancement of CNS lesions. · The contrast effect at different field strengths. · The effective time-window for the enhancement of blood-brain barrier damage. · The relations between the concentration of contrast agent and enhancement in p
Supportive legislation and improving technologies are making bioenergy an increasingly attractive energy source for Europe both economically and environmentally. However, abundant resources remain untapped across many member states in the European Union (EU). The Bioenergy Network of Excellence (NoE) entitled Overcoming Barriers to Bioenergy in Europe is charged with the task to identify critical
How can qualitative, ethnographic and emotional aspects from probe users be mapped at the same time as they get something meaningful in return? The emphasis is here on intellectual rewards during probe work rather than future good designs that in a long term perspective can be beneficial for the probe user. This case study has elaborated the traditional use of cultural probes [1] with a selection
Based on a case study of a telecom company’s transition towards more software value in their products, we describe and discuss SCM issues related to when traditional manufacturers go from a “hardware focus” to a mixed product configuration. Although software supply chain is not much discussed in logistics, it seems that logistics/SCM frameworks also fit many software supply issues. A specific soft
Quality requirements complement functional requirements with information on the target quality levels of software functions or emergent system quality aspects. In release planning the allocation of development effort in further investments into product enhancements, new or enhanced functions are competing with quality improvements for limited resources. When setting balanced quality targets for de
The Sixth Sense of PR-Experts? An Expert-Novice-Comparison of PR-Problem-Solving and Implications for Public Relations-Pedagogy
This thesis deals with tools for operational improvement of supply chain performance. The work was aimed at providing knowledge for supply chain developers and practitioners, and identifying and developing tools for improved performance in a supply chain. The investigation was part of a project financed by the European Commission called "Industrial Supply Chain Optimizer" (ISCO). The thesis consis
