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Background: Extended reality (XR), encompassing technologies such as virtual reality, augmented reality, and mixed reality, has rapidly gained prominence in health care. However, existing XR research often lacks rigor, proper controls, and standardization. Objective: To address this and to enhance the transparency and quality of reporting in early-phase clinical evaluations of XR applications, we
Developing accurate large-scale drought prediction models is challenging due to the complex temporal and spatial correlation patterns that govern drought dynamics, as well as the compounding effects of anthropogenic activities and global climate change. Although recent advances in deep learning have yielded effective drought prediction models, many struggle to fully capture the heterogeneous spati
Background: Psychiatric disorders have been associated with venous thromboembolism (VTE). However, to our knowledge, no nationwide study has examined the familial association between VTE and psychiatric disorders. Objectives: We took a pedigree-based approach and examined the risk of psychiatric disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods:
Background: In Sweden, dental care for children and adolescents, including specialist orthodontic treatment, is publicly funded. This study aims to analyze the impact of sociodemographic factors on the distribution of publicly funded specialist orthodontic treatment in a mid-sized Swedish region. Methods: A registry-based cohort study was conducted in Region Östergötland, including individuals bor
Over the last decades, marketing literature has persistently been interested in how marketers and consumers alike engage with the past through past-themed brands, products, and services. However, our knowledge on past-themed marketing is scattered and treated in largely separated literature streams on retro, heritage, nostalgia, and vintage. This article reviews marketing literature on retro, heri
In septic shock, administration of large fluid volumes is associated with poor outcomes. Recent evidence shows that non-resuscitation fluids are the major modifiable source of fluids for patients with septic shock in intensive care units (ICUs). This clinical trial is designed to test the hypothesis that restrictive administration of non-resuscitation fluids improves outcomes compared to usual car
The presence of microplastics (MPs) in water represents a current problem for marine life and a future serious issue for human health. This is pushing towards new approaches for the removal of MPs and, hence, their characterization and evaluation, which up to now has represented a limit for tentative procedures for their degradation. Herein, we reported on a new facile, in situ and non-destructive
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of higher − compared with standard − initial doses of surfactant in high-risk preterm infants and preterm infants with respiratory distress syndrome.
As novel, anti-amyloid therapies have become more widely available, access to timely and accurate diagnosis has become integral to ensuring optimal treatment of patients with early-stage Alzheimer's disease (AD). Plasma biomarkers are a promising tool for identifying AD pathology; however, several technical and clinical factors need to be considered prior to their implementation in routine clinica
Identifying patients at high risk of bone fracture is an important task. The clinical risk assessment, based on measurements of bone mass, correlates with strength but not toughness and is insufficient for reliable identification of high-risk patients. Starting from non-linear fracture mechanics, we hypothesise that reduced bone tissue fracture toughness and characteristic length, possibly in comb
Measurements of the stable carbon isotope ratio in methane (δ13C-CH4) are used in determining the source of CH4 emissions on local, regional, and global scales. To achieve the required level of data comparability for atmospheric monitoring networks, accurate gas reference materials of δ13C-CH4 in air are required with high levels of reproducibility. We describe a method to determine the δ13C-CH4 o
Background and aims: Heart transplantation is the preferred treatment for selected patients with end stage heart failure. Kidney function often declines after heart transplantation. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) slow the decline in eGFR in different populations. However, the effect of SGLT2i on kidney function in heart transplant recipients is unknown. Methods: The Dapaglifloz
This chapter delves into the evaluation of national innovation policies through a case study of the Brazilian National Innovation Policy (NIP). Assessing these policies poses several challenges, including the difficulty of defining and measuring policy outcomes, the scarcity of reliable data, and the intricacies of interactions among various stakeholders involved in the policy. Additionally, polit
As the global energy transition progresses, a range of drivers and barriers will continue to shape consumer attitudes and behavioural intentions towards emerging low-carbon technologies. The innovation-decision process for technologies composing the residential sector such as hydrogen-fuelled heating and cooking appliances is inherently governed by the complex interplay between perceptual, cogniti
Arid mountainous regions are vulnerable to extreme hydrological events such as floods and droughts. Providing accurate and continuous rainfall records with no gaps is crucial for effective flood mitigation and water resource management in these and downstream areas. Satellite data and geospatial interpolation can be employed for this purpose and to provide continuous data series. However, it is es
INTRODUCTION: We sought to harmonize genotype data from the predementia AMYPAD (Amyloid Imaging to Prevent Alzheimer's Disease) Consortium, compute polygenic risk scores (PRS), and determine their association with global amyloid deposition. METHODS: Genetic data from five AMYPAD parent cohorts were harmonized, and PRS were computed for Alzheimer's disease (AD) susceptibility, cerebrospinal fluid (
Get married is the rite of passage that coincides with exit from the parental household, solemnizing the establishment of a new household and commitment to a sexual partner (Allan, G. et al, 2003:135), which is a ubiquitous phenomenon across human society. Almost all adult men and women seek to marry or form a permanent stable relationship with another person for the sake of bear children and rais
Definition: The Mbuluzi River runs through Swaziland and Mozambique into the Indian Ocean. Due to water shortage, population increase and growing industrial and agricultural sectors, high stress is being put on the water quality. The importance of keeping good water quality is accentuated by the fact that the River is shared between two countries and that it supports both capitals with drinking wa
