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Background Open abdomen (OA) treatment often results in difficulties in closing the abdomen. Highest closure rates are seen with the vacuum-assisted wound closure (VAWC) technique. However, we have experienced occasional failures with this technique in cases with severe visceral swelling needing longer treatment periods with open abdomen. Feasibility and short-term outcome of a novel combination o
Extraction systems for hydrophobically tagged proteins have been developed based on phase separation in aqueous solutions of non-ionic detergents and polymers. The systems have earlier only been applied for separation of membrane proteins. Here, we examine the partitioning and purification of the amphiphilic fusion protein endoglucanase I(core)-hydrophobin I (EGI(core)-HFBI) from culture filtrate
In Sweden a new red list was issued 2000, but there is no published list of the most important areas for biodiversity preservation. I use woodliving and red-listed beetles as indicators of “hot-spots” for biodiversity preservation, since these insects constitute a large proportion of the red-listed forest living species in Sweden. Based on museum and many large private collections of beetles from
A new type of triangular phase diagram has been developed in which both the volume fractions and the shrinkage modes can be visualised and compared for the consolidation process in the paper dryer. The triangular phase diagrams show the development of the solid, the liquid and the gas volume fractions as well as the shrinkage relative to either ideal or no shrinkage of the sheets. Analysis showed
Popular Abstract in Swedish Parkinsons sjukdom uppstår när celler som producerar signalsubstansen dopamin i hjärnan dör. Detta leder till att de drabbade patienterna blir stela, får långsamma rörelser, svårt att påbörja och avsluta rörelser och även skakningar i framförallt armar och händer. Idag finns inget sätt att bota sjukdomen. Dock finns det läkemedel som kan lindra symptomen. Den vanligasteThe main pathological feature in Parkinson's disease is the progressive loss of dopamine neurons in the midbrain, which in turn leads to the appearance of motor deficits such as akinesia/bradykinesia (loss/slowness of movements), rigidity, postural imbalance and tremor. To this day, there is no cure for the disease, but there are medications to relieve the symptoms. The gold standard medication is
Objective: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). Material and Methods: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomat
Peptidoglycan from Staphylococcus aureus mobilized CD66b in human neutrophils but did not upregulate surface activation markers in eosinophils. In addition, Toll-like receptor 2, implicated in the recognition of peptidoglycan, was detected on the surface of resting neutrophils but not on eosinophils. These findings suggest roles for neutrophils but not eosinophils in innate recognition of peptidog
We have previously shown that porcine aortic endothelial cells expressing the Y934F platelet-derived growth factor (PDGF) beta-receptor mutant respond to PDGF-BB in a chemotaxis assay at about 100-fold lower concentration than do wild-type PDGF beta-receptor-expressing cells (Hansen, K., Johnell, M., Siegbahn, A. , Rorsman, C., Engstrom, U., Wernstedt, C., Heldin, C.-H., and Ronnstrand, L. (1996)
When a society plans the upbringing and education of its members, irrespective of age and level, one absolute requirement must be that it develops their ability of self-determination. A psycho-ecological approach to a study of the individual’s self-cognition (perception and evaluation) and self-determination (i.e. development of plans of action) focuses on the mutual relations existing between the
Sequential Monte Carlo (SMC) methods have demonstrated a strong potential for inference on the state variables in Bayesian dynamic models. In this context, it is also often needed to calibrate model parameters. To do so, we consider block maximum likelihood estimation based either on EM (Expectation-Maximization) or gradient methods. In this approach, the key ingredient is the computation of smoot
Abstract. Wigren M, Kolbus D, Dunér P, Ljungcrantz I, Söderberg I, Björkbacka H, Fredrikson GN, Nilsson J. (Malmö University Hospital, Lund University; Malmö University, Malmo; Sweden) Evidence for a role of regulatory T cells in mediating the atheroprotective effect of apolipoprotein B peptide vaccine. J Intern Med 2010; doi: 10.1111/j.13 65-2796.2010.02311.x. Objectives. Autoimmune responses aga
The aim of this paper is to compare the socio-spatial patterns of innovation and knowledge linkages of a biopharmaceutical and an agro-food biotech cluster. Dissimilarities can be expected based on differences in terms of historical technological regimes and sectoral innovation system dynamics between the agro-food and pharmaceutical industries in general and particularly the distinctive analytica
Abstract OBJECTIVE: Anaemia is a common complication of renal failure. It can be treated with erythropoietin (EPO) administration, red blood cell transfusion (RBCT), or a combination of both. EPO has been registered for the treatment of renal anaemia in Sweden since the beginning of the 1990s, and is the primary treatment regimen for anaemia related to renal failure. The objective of this study wa
Abstract Objective. To demonstrate how patients' probability of having chronic kidney disease (CKD) stage 3-5 (measured GFR <60 mL/min/1.73 m(2)) can be predicted from a specific value of estimated glomerular filtration rate (eGFR). Material and methods. The probability of CKD stage 3-5 was predicted from a logistic regression model (n = 850) using three different eGFR prediction equations: Lund-M
The marriage squeeze in China, whereby the sex ratio imbalance leaves many males without a marriage partner, is not only about numbers, but also about how the institution of marriage is socially, economically, and politically underpinned. This paper uses the concept of ecology of choice in mate selection to demonstrate how different social processes and practices have ramifications on who can marr
Background: Renal insufficiency is a serious complication of lithium treatment. Therefore, regular monitoring of plasma (P) creatinine is always part of lithium treatment safety routines. Recently P-cystatin C-estimated glomerular filtration rate (cystatin C-eGFR) had been launched as a preferable alternative to P-creatinine. Aims: To find out which of the two alternatives to prefer in the safety
Background: Computed tomography (CT) of the brain is performed with high local doses due to high demands on low contrast resolution. Advanced algorithms for noise reduction might be able to preserve critical image information when reducing radiation dose.PurposeTo evaluate the effect of advanced noise filtering on image quality in brain CT acquired with reduced radiation dose. Material and Method
Mitochondrial dysfunction is an important cause for neonatal liver disease. Disruption of genes encoding oxidative phosphorylation (OXPHOS) components usually causes embryonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondrial disease with liver and kidney involvement, caused by a homozygous BCS1L mutation (232A>G). This
