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Tyrosine kinase inhibitors targeting the BCR-ABL oncoprotein in chronic myeloid leukemia (CML) are remarkably effective inducing deep molecular remission in most patients. However, they are less effective to eradicate the leukemic stem cells (LSC), resulting in disease persistence. Therefore, there is great need to develop novel therapeutic strategies to specifically target the LSC. In an experime
The purpose of this work was to present collective data on firefighter fatalities in Sweden between 1937 and 2016. Data presented is directly related to operations only. Fatalities due to long-term exposure of gases, particles, and physical/psychological stress or similar were not included in the study. Also, accidents involving ambulances as well as fatalities in direct relation to physical trainThe purpose of this work was to present collective data on firefighter fatalities in Sweden between 1937 and 2016. Data presented is directly related to operations only. Fatalities due to long-term exposure of gases, particles, and physical/psychological stress or similar were not included in the study. Also, accidents involving ambulances as well as fatalities in direct relation to physical train
Objective To explore healthcare providers’ perceptions of the current postpartum care (PPC) practice and its potential for improvement at governmental health institutions in low-resource suburbs in Dar es Salaam, Tanzania. Design Qualitative design, using focus group discussions (8) and qualitative content analysis. Setting Healthcare institutions (8) at three levels of governmental healthcare in
Creatine kinases are important in maintaining cellular-energy homeostasis, and neuroprotective effects have been attributed to the administration of creatine and creatine-like compounds. Herein we examine whether ablation of the cytosolic brain-type creatine kinase (B-CK) in mice has detrimental effects on brain development, physiological integrity or task performance. Mice deficient in B-CK (B-CK
Previous studies including various tumor types have shown different associations between tumor tissue levels of plasminogen activator inhibitor 2 (PAI-2) and patient survival. High tumor tissue concentrations of PAI-2 have been associated with good prognosis in patients with breast cancer, small cell lung cancer and ovarian cancer, but with poor histologic differentiation and poor prognosis in pat
Objective. Patients with inflammatory bowel disease (IBD) often have low iron stores or anaemia. There is controversy about whether iron should be supplemented orally or intravenously (i.v.). The purpose of this study was to investigate whether treatment with intravenous iron is superior to treatment with oral iron. The primary end-points were response and remaining anaemia at the end of treatment
Malmö Stad Stadsfastigheter is planning to set up solar collectors in the town district of Augustenborg in Malmo. The purpose of this report, Solar system in Augustenborg – a preliminary study, is to supply a foundation for the employer Malmö Stad Stadsfastigheter, as a guide to how the solar collector project should be implemented. The report describes how solar systems work and how heat can be e
Background and purpose - Little is known about the comparative performance of patient-reported outcome measures in revision hip arthroplasty. We compared the performance of the WOMAC, the SF-36, the EQ-5D, and a pain-related visual analog scale (VAS) in revision hip arthroplasty. Methods - 45 patients with aseptic prosthetic loosening following primary hip arthroplasty completed the WOMAC, the SF-
The aim of our study was to investigate conceptions about gender, gender expression and sexuality among social work students. We did this by asking what differences in conceptions about gender, gender expression and sexuality are noticeable among the students. We also asked how the students’ experience that these conceptions appear throughout the educational program, and what importance they give
This thesis takes its stance in the AstraZeneca judgment from the General Court and the latest developments in EU competition law and compares these with the equivalent standards of US antitrust law. Focus is on similarities and divergences between the EU application of competition law and the more developed doctrines of Walker Process and Noerr-Pennington in the US. The analysis is made in respec
The European Single Market is built on a patchwork of contract laws and according to the European Commission’s findings differences between contract laws of the respective Member States substantially complicate cross-border trade. More specifically, the fragmentation of contract laws contributes to increasing legal complexity and costs for businesses while lowering consumers’ confidence in shoppin
Research on mental health (MH) help-seeking behavior is still trying to understand influencing factors that hinder individuals in obtaining professional help. This becomes particularly important as young adults show a high prevalence of mental illness (MI) but a low prevalence of seeking help. So far, MH stigma resulting from self-directed and public attitudes, emotions and behaviors has been cons
The present thesis aims to assess the efficacy of the GDPR in managing personal data breaches in healthcare. To fulfil its purpose, we have analysed the legal basis for processing sensitive personal health data and we have set the following research question: To what extent does the GDPR prevent personal health data breaches as well as mitigate their impact on data subjects? In order to conduct
Purpose: Elevated cardiac troponin levels have been shown to be associated with a poor prognosis under some intensive care conditions. This study investigated whether inclusion of high-sensitivity troponin T (hsTnT) increased the prognostic accuracy of the Simplified Acute Physiology Score (SAPS 3) for general intensive care unit (ICU) patients, cardiac arrest patients, or patients with a non-card
CFE wp- Nr 19 1Temporality in the Construction of EU Identity Temporality in the Construction of EU Identity Anders Hellström anders.hellstrom@svet.lu.se Bo Petersson bo.petersson@svet.lu.se 2 CFE Working paper series no. 19 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06 Sweden Email: cfe@cfe.lu.se CFE Working paper series
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp19.pdf - 2026-07-12
