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The field of biomedicine is constantly investing significant research efforts in order to gain a more in-depth understanding of the mechanisms that govern the function of body compartments and to develop creative solutions for the repair and regeneration of damaged tissues. The main overall goal is to develop relatively simple systems that are able to mimic naturally occurring constructs and can t
Researchers selecting probands for molecular genetic studies confront a range of sampling issues with modest empirical guidance. In this paper, using cases of major depression (MD), anxiety disorders (AD) alcohol use disorder (AUD), drug use disorder (DUD), bipolar disorder (BD) and schizophrenia (SZ) from a large population cohort of all native Swedes born 1940–2003, we examine the implications o
LONG-TERM depletion of ozone has been observed since the early 1980s in the Antarctic polar vortex, and more recently at mid-latitudes in both hemispheres, with most of the ozone loss occurring in the lower stratosphere1. Insufficient measurements of ozone exist, however, to determine decadal trends in ozone concentration in the Arctic winter. Several studies of ozone concentrations in the Arctic
Popular Abstract in Swedish Avsaltning av havsvatten utgör en viktig källa för vattenförsörjning till befolkningen som bor vid Persiska viken, Medelhavet och Röda havet. De tre regionerna utgör ca 11,8 % av världens landyta och hade omkring 9 % av världens befolkning under 1950 och 2008, samt lika mycket enligt prognos för år 2050. Dessa områden är hemvist för 62 %, 58% och 60% av världens avsaltnIn this M.Sc. Thesis of a comparison for sewerage system of the three main municipalities of Turkish Republic of Northern Cyprus (T R N C) has been studied and discussed. The study covers the future population calculations for three municipalities, Nicosia, Famagusta and Kyrenia, by means of Turkish and European standards. The comparisons for sewerage system of the three municipalities are compare
This commentary discusses the role of increasingly artificial intelligence-infused big tech platforms in facilitating and normalising high-emission lifestyles and consumption practices. It introduces the notion of algorithmically facilitated emissions to initiate a shift from a logic of ‘climate collapse by design’ to a logic of ‘emissions reduction by design’. Reducing consumption-based emissions
The maximum drawdown of a stochastic process is the largest peak-to-troughdecline observed over a given horizon [0, T]. Using arguments from extremevalue theory, we derive the limiting distribution of the maximum drawdown fora Brownian motion with positive drift as T → ∞. We show that, after suitablecentering and scaling, the maximum drawdown converges in distribution to theGumbel law.
OBJECTIVES: The Sepsis-3 definition states the clinical criteria for sepsis but lacks clear definitions of the underlying infection. To address the lack of applicable definitions of infection for sepsis research, we propose new criteria, termed the Linder-Mellhammar criteria of infection (LMCI). The aim of this study was to validate these new infection criteria.DESIGN: A multicenter cohort study o
The purpose of this paper is to show how requirements engineering techniques can be used to structure the development of non-technical aspects of socio-technical systems, such as guidelines. An adapted requirements engineering approach was chosen to elicit requirements for resilience guidelines within an EU Horizon 2020 multi-national project aimed at developing resilience guidelines for crisis ma
We propose a non-intrusive reduced basis (RB) method for parametrized nonlinear partial differential equations (PDEs) that leverages models of different accuracy. From a collection of low-fidelity (LF) snapshots, parameter locations are extracted for the evaluations of high-fidelity (HF) snapshots to recover a reduced basis. Multi-fidelity Gaussian process regression (GPR) is employed to approxima
At MAX IV Laboratory, the Swedish Synchrotron Radiation (SR) facility, the largest of two rings operates at 3 GeV with a bare lattice emittance of 330 pm rad. Upgrade plans are under consideration aiming at a gradual reduction of the emittance, in three stages: a short-term with an emittance reduction of 20% to 40%, a mid-term with an emittance reduction of more than 50% and a long-term with an em
Context. Transmission spectroscopy is one of the most powerful techniques used to characterize transiting exoplanets, since it allows for the abundance of the atomic and molecular species in the planetary atmosphere to be measured. However, stellar lines may bias the determination of such abundances if their center-To-limb variations (CLVs) are not properly accounted for. Aims. This paper aims to
The MAX laboratory at Lund University, Sweden, today operates an accelerator system consisting of a 100 MeV racetrack microtron and a 550 MeV storage ring (MAX I). At the moment (July 1994) a new storage ring MAX II is near completion and will start first injections within 2 months. This work gives an overview of the MAX II project including the first beamlines and a description of the accelerator
The late nineteenth and early twentieth century saw a widespread interest in Asian religion within European and American esotericism. Whereas most of that interest was directed toward India, a number of representatives of the early twentieth-century esoteric environment turned toward East Asia in order to find what they hoped to be a spiritual solution to the problems of their time. One of these i
Fetal programming may arise from prenatal exposure and increase the risk of diseases later in life, potentially mediated by the placenta. The objective of this systematic review was to summarize and critically evaluate publications describing associations between human placental changes and risk of atopic disorders during childhood. The review adhered to the Preferred Reporting Items for Systemati
When does technological change lead to inclusive prosperity? Research suggests that shared benefits from technological progress require concurrent expansions in education and support from pro-labor institutions. We contribute to the debate by studying electricity adoption in Sweden during the first decades of the 20th century. Exploiting that proximity to hydro-power plants shaped the electricity
Three methods were developed for preparing alginate gels containing cells that are stable in phosphate containing media. In Method I preformed alginate beads containing entrapped cells were treated with polyethyl eneimine followed by glutaraldehyde. In Method II alginate sol was treated with a carbodiimide and N-hydroxysuccinimide (to form active esters), mixed with cells and extruded into calcium
