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Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen

Autoantibody-mediated diseases comprise a heterogeneous group of disorders in which the pathogenic potential of autoantibodies has been clearly demonstrated. In general, their treatment relies on the long-term use of systemic corticosteroids and other immunosuppressants that are associated with considerable adverse reactions. EndoS, an endoglycosidase derived from Streptococcus pyogenes, specifica

TRIPS and Technology Transfer

Abstract in UndeterminedTRIPS is a trade-off between the interest of the developed world in having its technology respected and the need for technology transfer especially to the least-developed countries. But this balance of interests is poorly expressed in the Agreement, which is primarily devoted to protection of intellectual property rights and only marginally addresses the other side of the c

Trading in sexual currency: Transactional sex, sexual coercion and sexual behaviours among young people in Uganda

The growing incidence and prevalence of sexually transmitted infections among young people, particularly HIV, is a public health concern in Uganda. There is increasing evidence that Ugandan youth engage in risky sexual behaviors, transactional sex, and experience sexual coercion. Most research on sexual behaviors has been limited to inter- and intra-personal factors that influence sexual behaviors