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However, it is not clear to what extent corresponding perceptual preferences for intonational deviations might rely on listeners’ instrumental expertise or such contextual aspects as the metrical placement of tones. We investigated higher-education music students’ perceptual preferences for melodic intonation of local leading tones in unaccompanied classical violin performances. Recordings of 12 e
AimTo fully take advantage of blood test results, comparative data are required. Today, the reference interval is a commonly used concept. This review aims to summarise the current state of reference intervals, focusing on infants.MethodsLiterature on reference percentiles (birth to 12 months of age) published from January 1950 until November 2024 was reviewed. Search terms comprised paediatric, i
INTRODUCTION: Breast cancer, a leading female cancer worldwide, can be influenced by mitochondrial dysfunction. Dysregulation of mitochondria by the nuclear genome may cause breast cancer initiation and progression. However, the comprehensive investigation of mitochondrial-related genes as prognostic marker for the overall survival of early-stage breast cancer patients is still limited.METHODS: To
This is the third of three chapters on diffusion MRI acquisition for tractography. Tractography is performed extensively in the in vivo adult brain, and sequences used for the in vivo adult brain have been covered in detail in Chapter 7. However, tractography is also performed in ex vivo human brain, in both the in vivo and ex vivo animal brain of various nonhuman species, in the human brain durin
With the advent of digitalization, the economy of the world is quickly changing itself and Indian Small and Medium Enterprises (SMEs) are the front runners. This study sheds light on how digital transformation is crucial to support the growth, competitiveness, and sustainability in the present business environment, and how digital transformation is important to the SMEs in India. To encourage SMEs
Rapid and accurate generation of building damage maps (BDMs) following earthquakes is crucial for effective disaster response and rescue operations. With the increasing availability of optical very high-resolution remote sensing (OVHR-RS) images, two considerable deep learning challenges arise: (1) developing robust models for data-rich regions and (2) adapting pre-trained models for areas with li
Recent years have seen a sharply rising interest in the scientific area dedicated to the study of the use of Artificial Intelligence (AI) for Cognitive Behavioral Therapy (CBT) research and applications (AI4CBT for brevity). Yet, little is known about how this interest is realized and hence the overall status, prospects, and possible challenges of AI4CBT as a field (e.g. breadth of the field, key
INTRODUCTION: Biomarkers play a crucial role in understanding Alzheimer's disease (AD) pathogenesis and treatment effects. However, comparing biomarker measures without standardization and appreciating their magnitude relative to the disease can be challenging. METHODS: To address this issue, we propose the CentiMarker approach, similar to Centiloid, which provides a standardized scale between nor
Corrosion of steel components embedded in concrete is detrimental to the structural integrity and their intrinsic function,such as the leak-tightness of containment liners in nuclear reactor containment buildings. Detection of embedded linercorrosion is a challenging task due to the concrete’s heterogeneity and the large dimensions of containment buildings.This initial study explores early-stage d
Purpose: To describe a novel technique for optimal orientation and accurate deployment of aortic endografts during complex endovascular aortic repair (cEVAR). Technique: After establishing the femoral access in the standard fashion, a long large-bore dilator is inserted before the cEVAR delivery system. The dilator is advanced beyond the renovisceral segment noticing the degree of axial rotation.
DNA-encoded chemical libraries are increasingly used in pharmaceutical research because they enable the rapid discovery of synthetic protein ligands. Here we explored whether target-class focused DNA-encoded chemical libraries can be cost-effective tools to achieve robust screening productivity for a series of proteins. The study revealed that a DNA-encoded library designed for NAD+-binding pocket
Male gametogenesis occurs directly after uptake of malaria parasites by the mosquito vector and leads to the release of eight nucleated flagellar gametes. Here, we report that one of the two parasite actin isoforms, named actin II, is essential for this process. Disruption of actin II in Plasmodium berghei resulted in viable asexual blood stages, but male gametogenesis was specifically inhibited.
This paper introduces a conceptual framework: the CPS triangle, which has evolved over four years of research on ‘older people meet robots’. It is a synthesis of domestication theory, modern social practice theory and empirical data. Case studies on the domestication of one current technology, the robotic vacuum cleaner, and two emergent technologies, the eHealth system and the service robot, prov
Numerous theories of distributive fairness promote the idea that we ought to give extra weight to benefits to the worse off and can thereby be seen as promoting gap closures. This paper underlines the relevance of making a distinction between attainable and ideal target levels for individuals in populations affected by distributive fairness and show that in cases of scarce resources, theories that
This study analyzes the current state of artificial intelligence (AI) technologies for addressing and mitigating climate change in the manufacturing sector and provides an outlook on future developments. The research is grounded in the concept of general-purpose technologies, motivated by a still limited understanding of innovation patterns for this application context. To this end, we focus on gl
Family disaster planning and preparation demands proactive acknowledgment and accommodation of individuals with disabilities. This study, based on interviews with families including members with disabilities, uncovers insights on information gaps, adaptive strategies, technology use, and support networks. Contributing to disaster and disability studies, resilience, and crisis planning, it highligh
