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PtdIns-4,5-bisphosphate is a lipid messenger of eukaryotic cells playing critical roles in processes such as cytoskeleton organization, intracellular vesicular trafficking, secretion, cell motility, regulation of ion channels and nuclear signalling pathways. The enzymes responsible for the synthesis of PtdIns(4,5)P(2) are phosphatidylinositol phosphate kinases (PIPKs). The moss Physcomitrella pate
Post-disaster coordination is an essential aspect to achieve sustainable disaster recovery. However, to date, little attention has been paid to the subject of coordination in disaster recovery in comparison to response coordination. This study is an investigation into the factors affecting coordination for sustainable disaster recovery. It uses the case-study of Eden district Municipality in South
To improve population health, it is important to create environments that support activity, participation and health. One crucial aspect concerns the degree to which the built environment is accessible for all people including those with reduced functional capacity. The overarching objective of this thesis was to explore and further develop methodology for accessibility assessments based on the no
The open and closed forms of ozone and the path connecting them through a transition state, in C-2v symmetry, are explored using the multi-state, multi-configurational second order perturbative method, MS-CASPT2. It is demonstrated that, by using an ANO-L triple-zeta basis set, it is possible to set up an active space able to describe the otherwise troublesome transition state region. Both a conic
Lion faecal samples, collected in the field between 1 hour to 1 week after defecation were preserved in three different media (ethanol, ASL buffer and Two-step storage). The aim was to determine which faecal DNA field preservation method best enhances PCR amplification success. Samples stored in ethanol showed a significantly higher amplification success of microsatellite loci than samples stored
Conifer feeding bark beetles (Coleoptera, Curculionidae, Scolytinae) pose a serious economic threat to forest production. Volatiles released by non-host angiosperm plants (so called non-host volatiles, NHV) have been shown to reduce the risk of attack by many bark beetle species, including the European spruce bark beetle, Ips typographus. However, the most active blend for I. typographus, containi
Although climate is known to be one of the key factors determining animal species distributions amongst others, projections of global change impacts on their distributions often rely on bioclimatic envelope models. Vegetation structure and landscape configuration are also key determinants of distributions, but they are rarely considered in such assessments. We explore the consequences of using sim
A dye-binding method using Acid Orange 12 was investigated regarding its suitability for the quantification of available lysine, as a means of monitoring the Maillard reaction in skim milk powders. The method was evaluated by analyzing a wide range of milk powders produced by three different drying methods and stored under various conditions. A pilot-scale freeze-dryer, spray-dryer and drum-dryer
To present a reduced version of the Housing Enabler, useful as a screening tool in practice contexts and in research, this study identifies the core items of the environmental component of the instrument, that is, the items most important in terms of the instrument's overall validity to measure accessibility problems. Utilizing cross-national data and interdisciplinary knowledge through an iterati
Alzheimer's Disease (AD) is the most prevalent form of dementia worldwide, yet the development of therapeutics has been hampered by the absence of suitable biomarkers to diagnose the disease in its early stages prior to the formation of amyloid plaques and the occurrence of irreversible neuronal damage. Since oligomeric A beta species have been implicated in the pathophysiology of AD, we reasoned
Abstract The current Standard Model cannot explain many properties of the neutrino, including its mass. Models exist where a postulated heavy Majorana neutrino will give rise to the observed small neutrino mass currently observed. This thesis presents a search for indications of Majorana neutrinos with focus on finding heavy neutrinos and W_R-bosons predicted by the Left-Right Symmetric Model. Pro
Cerebral Palsy, commonly referred to as CP, is a neurological disorder that results in loss or impairment of motor function, which affects body movement, muscle control, muscle coordination and balance. In Sweden, about 200 children are diagnosed with Cerebral Palsy every year and the disorder can cause imbalances between the muscles. These imbalances can lead to contractures which is equiva- lent
Title Physiotherapeutic interventions for the treatment of shoulder dysfunction after neck dissection – a literature review Background Neck dissection is a surgical procedure used in treatment of head and neck cancer. Shoulder dysfunction and pain are common consequences due to this procedure. The physiotherapeutic treatment of the shoulder is both important to prevent adhesive capsulitis and res
Principen om skyldigheten att skydda är kontroversiell och har varit det sedan International Commission on Intervention and State Sovereignty introducerade principen. Principen antogs enhälligt av Förenta Nationernas medlemsstater 2005 och verkade vara ett nytt sätt att skydda medmänskliga värden. Principen om skyldigheten att skydda används för att skydda befolkningen inom stater där staterna sjäThe responsibility to protect is a controversial principle and has been ever since it was introduced by the International Commission on Intervention and State Sovereignty in 2001. Unanimously adopted by the United Nations member states in 2005 the principle seemed to be a new way of protecting humanitarian values. To protect the citizens of states when the states themselves are unwilling or unable
Potato protein is an industrial side product with highly desirable properties which can be utilized if the toxic glycoalkaloids can be removed in a gentle way which doesn’t damage the protein. The challenge within this project is to find an extraction technique efficient enough to remove the toxic glycoalkaloids, but still mild enough to preserve the protein from denaturation. Supercritical CO2 ex
3D printing of metal components is a growing industry where the demand of highly precise and complicated geometrical metal structures are met. Höganäs is with its Digital Metal department one of the few companies that do 3D-printing by powder bed ink-jet technique. In this technique a binding material is needed in order to retain the designated structure until sintering. In this project a 316 L g
Upphovsrätter ger upphov till både ekonomiska och ideella rättigheter. Den ideella rätten bygger på en tanke om att upphovsmän har ett starkt personligt intresse och en koppling till sina verk. Samma tanke ligger bakom det överlåtelseförbud som finns i 28 § lag (1960:729) om upphovsrätt till litterära och konstnärliga verk (URL). Förbudet gör det otillåtet för en förvärvare av en upphovsrätt att öCopyright is composed of two rights, the economic and moral rights. The moral rights are built on the thoughts that the creator of the copyright has a strong personal interest and a connection to its creation. It is the same thoughts that are behind the transfer prohibition in 28 § lag (1960:729) om upphovsrätt till litterära och konstnärliga verk (URL). The prohibition makes it illicit for the as
The financing of energy efficiency measures and renovations is key to reaching energy efficiency targets for the housing sector. The purpose of this article is to add the Swedish case of how capital market funds have become accessible and used by public and private housing companies, in particular for energy efficiency measures. The core of this article are interviews with representatives of Swedi
To reduce the load on the operator of an unmanned aerial vehicle (UAV) during long search and rescue, and monitoring missions, the concept of an automatic system is proposed, which directly on board performs a prelimi-nary analysis of images received from a high-resolution navigation video camera, determines areas of interest, and sets the position of an additional camera with a reduced viewing an
