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Collecting enough labeled images to train an artificial neural network (ANN) is a common struggle since the process is tedious, time consuming and expensive. CellaVision, a company that creates analyzers that automate the process of finding and pre-classifying abnormal blood cells using machine learning, runs into this problem regularly. When new generations of analyzers are being produced, the im
The purpose of this study is to explore what organisational capabilities are needed to monetise on the value of a digital transaction platform during a business model transformation. The study brings forward six capabilities which are divided into the three themes: enable, create and capture. To enable value on the platform, the capabilities innovative mindset and supportive leadership are assumed
Att bygga material av proteiner är en konst som våra kroppar är specialister på. Men när vi medvetet försöker designa proteinmaterial, så blir det tydligt hur komplexa och svårstyrda biofysikens lagar är. Det här examensarbetet har som mål att lägga grunden för ett proteinmaterial som kan skapas eller dissociera som respons på förändrad Ca2+-koncentration. Om ett sådant material kan framställas meTo build materials of proteins is an art that nature is a specialists in. But when we actively try to design protein materials, it becomes clear how complex and hard to control the biophysical world is. This master thesis aims to lay the foundation for a protein material that forms and dissociates as a response to changed Ca2+ concentration. If such a material is to be produced with an ordered str
Execution time is an important issue in the field of numerical analysis. Simulations are getting more and more complex and the execution times are rapidly increasing. In the scope of this thesis a time integration library is used to solve initial value problems. The aim of the thesis is to implement and investigate two different approaches to decrease the execution time for the library. The main f
During evolution the human brain has increased drastically in size compared to that of other primates. However, little is known about primate brain development as it is difficult to study human and primate brains in the laboratory due to the scarcity of tissues. Yet, it is essential to study primate brains and understand the molecular features leading to the human brain’s unique cognitive function
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15–20% of families fitting MODY criteria do not have mutations in any of the known genes. These families provide a rich resource for the identificat
An analytical procedure based on microwave-assisted extraction (MAE) and standard addition was applied for the determination of banned azo dyes in bovine, sheep, and goat leather. Standard addition at four different concentration levels was performed using azo dyes, dissolved either in methanol or water. All dyes were determined indirectly by measuring their corresponding harmful aromatic amines,
Galectins are implicated in a large variety of biological functions, many of which depend on their carbohydrate-binding ability. Fifteen members of the family have been identified in vertebrates based on binding to galactose (Gal) that is mediated by one or two, evolutionarily conserved, carbohydrate-recognition domains (CRDs). Variations in glycan structures expressed on glycoconjugates at the ce
Methods of analysing and interpreting two-dimensional velocity field data in order to understand the scales of turbulence of bubbly two-phase flow were developed. Reynolds decomposition and large eddy simulation (LES) decompositions (low-pass filtering), in conjunction with proper orthogonal decomposition (POD) energy spectra analysis, as well as adjusted convective decomposition (constant convect
The thesis uses, as a starting point for a discussion of emergency response management, the problem of gradual coordinated adaptation of management functions in relation to an event and its dynamics. Empirical observations and analyses carried out in the research project show that important problemsolving processes not included in, and sometimes diverging from, planning and preparations frequently
1 The effectiveness of antimuscarinic agents in the treatment of the overactive bladder (OAB) syndrome is thought to arise through blockade of bladder muscarinic receptors located on detrusor smooth muscle cells, as well as on nondetrusor structures. 2 Muscarinic M-3 receptors are primarily responsible for detrusor contraction. Limited evidence exists to suggest that M-2 receptors may have a role
Different functions for the programming of the cross flow in asymmetrical flow field-flow fractionation were studied with the aim to find the flow conditions most suitable for the molar mass distribution analysis of high molecular weight polysaccharides. A mixture of four differently sized pullulans covering the molar mass range 5.8 x 10(3)-1.6 x 106 g mol(-1) were used as a model sample. Two type
We analyze the propagation of electromagnetic waves in nonlinear, bianisotropic, nondispersive, homogeneous media using simple waves and six-vector formalism. The Maxwell equations are formulated as an eigenvalue problem, whose solutions are equivalent to the characteristic propagation directions. We solve the oblique incidence of plane waves in vacuum on a half space of nonlinear material, and pr
This paper aims to identify and review new and unproven emergency department (ED) methods for improved evaluation in cases of suspected acute coronary syndrome (ACS). Systematic news coverage through PubMed from 2000 to 2006 identified papers on new methods for ED assessment of patients with suspected ACS. Articles found described decision support models, new ECG methods, new biomarkers and point-
Background: With todays’ requirement of shorter product life cycles and faster time-to-market, producing companies experience an increased demand for faster transports in the supply chain. This puts pressure on freight forwarders to offer their customers a timely and reliable transport service at a reasonable price. Another challenge for the freight forwarders in Sweden is to provide such services
The world around us is urbanising at a faster rate than ever. Today more than 70 per cent of the European population lives in urban areas, especially small and medium-sized cities. Often, cities are the centres of economic growth. In the context of urban pollution and climate change, cities are at the core of European policies due to their ability to be the ‘places’ where solutions and innovations
The WEEE Directive requires the producers to fulfil e-waste compliance according to the extended producer responsibility (EPR) principle. In order for producers to comply with the requirements nationally, collective compliance schemes were formed. Usually the manufacturers join together and form producer responsibility organisations (PROs) which take the responsibility for organising the waste man
