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Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment inter
Marfan syndrome (MFS) is a hereditary connective tissue disorder with an estimated prevalence of 1:5000–1:10 000 individuals. It is a pleiotropic disease characterized by specific ocular, cardiovascular, and skeletal features. The most common cardiovascular complication is aortic root dilatation which untreated can lead to life-threatening aortic root dissection, mainly occurring in adult patients
Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates
Lund University School of Economics and Management In order to complete your admission process to Lund University you have to submit an online application. It is only possible to submit an application during the application periods. Application processAfter you have been nominated by your home university, you will receive an activation email with further instructions on how to log in to the mobili
https://www.lusem.lu.se/study/international-opportunities/incoming-exchange-students-lusem/how-apply-exchange-student - 2026-07-02
An ongoing discussion whether traditional toxicological methods are sufficient to evaluate the risks associated with nanoparticle inhalation has led to the emergence of Air-Liquid interface toxicology. As a step in this process, this study explores the evolution of particle characteristics as they move from the airborne state into physiological solution. Airborne gold nanoparticles (AuNP) are gene
Radiative lifetimes of 17 high-lying excited states in Rh I aremeasured using the time-resolved laser-induced fluorescence method. Out of these lifetimes, 13 are new and the remaining four confirm previous measurements. Furthermore, we report the first theoretical investigation of Rh I, where the radiative decay properties of all experimentally known levels below 47 000 cm(-1) are calculated using
Thiopurine S-methyltransferase (TPMT) deficient patients develop life threatening haematotoxicity (for example, pancytopenia) when treated with a standard dose of azathioprine (AZA) and 6-mercaptopurine (6-MP) due to excessive accumulation of cytotoxic metabolites. At present, it is generally recommended that these patients should not receive AZA or 6-MP treatment for inflammatory bowel disease. W
A national debate about how to transform and to ‘green’ the problematic housing stocks from the boom era has been going on since the late 1990s. Different kinds of policy instruments with energy efficiency objectives that address either energy systems, energy sources or construction and renovation of the building envelope have been in use. Some policy instruments have combined green objectives wit
This study is an attempt to take advantage of a cerebellar model to control a biomimetic arm. The cerebellar controller is a modified MOSAIC model which adaptively controls the arm. We call this model ORF-MOSAIC (Organized by Receptive Fields MOdular Selection And Identification for Control). The arm features a musculoskeletal model which is controlled through muscle activations by means of optimi
At Dagsmosse in south-central Sweden, evidence from well-preserved Mesolithic wetland sites (10,200–7000 cal a BP) demonstrates occupation continuity among Hunter-Gatherer-Fisher (HGF) communities in wetland areas. This study presents detailed environmental reconstructions of the Dagsmosse basin, where Mesolithic fishing and dwelling activities were recorded. Focusing on the Preboreal–Boreal biozo
Psykiskt störda lagöverträdare har ofta inte samma förutsättningar som andra att följa lagen då de kan ha en annan föreställning av, eller en annan förmåga att resonera kring, verkligheten. Det är vår föreställning av verkligheten som ger oss skäl att göra eller att inte göra vissa saker, och vår uppfattning om vilka följder vårt handlande kommer att få, får betydelse för om vi företar handlingen Mentally disordered offenders often do not have the same preconditions as others to follow the law as they may have a different perception of, or a different ability to reason about, reality. It is our perception of reality that gives us reason to do or not do certain things, and our perception of the consequences our actions will have has an impact on whether we undertake them or not. If you have
Solvent cage-escape dynamics of bimolecular photoredox products in solution has been investigated computationally through a combination of molecular dynamics simulations and quantum chemical calculations. The present work focuses on the photoinduced oxidation of the organic electron donor dimethylaniline (DMA) by a Fe(III) N-heterocyclic carbene photosensitizer (Fe(III)NHC+) in two different solve
Background and Aims. While the rationale for coronavirus disease 2019 (COVID-19) vaccination is to reduce complications and overall mortality, some cardiovascular complications from the vaccine itself have been demonstrated. Myocarditis and pericarditis are recognized as rare acute adverse events after mRNA vaccines in young males, while evidence regarding other cardiovascular events remains limit
We use a closed-loop algorithm to accurately program hafnium zirconium oxide (HZO) ferroelectric tunnel junctions (FTJs) to arbitrary chosen target conductance values. The key enabler is suppression of conductance growth. We have identified two different mechanisms contributing to the total conductance of FTJs. By controlling both, we demonstrated an up to threefold increase of the usable conducta
Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women
Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a nuclease and NTPase protein, suggesting that additional nucleic acid-targeting systems remain to be understood. Here we develop large-scale compa
Long RSH enzymes, Rel and RelA, are master regulators of bacterial (p)ppGpp alarmones levels. Bifunctional Rel transitions between a compact hydrolysis-competent (HD ON) state, a relaxed catalytically inactive (HD OFF/SYNTH OFF) state, and an elongated synthesis-competent (SYNTH ON) state, whereas RelA samples only the latter two. The distribution of these states is controlled by starved ribos
