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Abstract P4-09-03: On the development and clinical value of RNA-sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: A report from the population-based multicenter SCAN-B study

Background:In early breast cancer, five histopathological biomarkers are part of current clinical routines and used for determining prognosis and treatment: estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (ERBB2/HER2), Ki67, and Nottingham histological grade (NHG). We aimed to develop classifiers for these biomarkers based on tumor mRNA-sequencing (RNA

On the date of composition of Additions B and E to LXX Esther

Additions B and E to LXX Esther have been variously dated from the second century BCE to the first century CE. This study links the two Greek Additions, on the one hand, with Philo’s writings through the concept of the “evil-hating justice” and, on the other hand, with the historical persons and events related to the Jewish-Alexandrian conflict of 38-41 CE, and dates their composition or final red

VADEMECUM, 77 Minor Terms for Writing Urban Places: Minor Urbanism

Writing Urban Places proposes an innovative investigation and implementationof a process for developing human understanding ofcommunities, their society, and their situatedness. By recognising thevalue of local urban narratives – stories rich in information regardingcitizens socio-spatial practices, perceptions and expectations – theAction aims to articulate a set of concrete literary devices with

Analyzing structural stratification in the Swedish higher education system : data contextualization with policy-history analysis

20th century massification of higher education and research in academia is said to have produced structurally stratified higher education systems in many countries. Most manifestly, the research mission of universities appears to be divisive. Authors have claimed that the Swedish system, while formally unified, has developed into a binary state, and statistics seem to support this conclusion. This

Bicycle planning – A literature review

Ökad cykling har stor betydelse för ett hållbart transportsystem. För att öka andelen resor med cykel måste dock trafik- och cykelplaneringen ta itu med ett flertal olika problem. Det är emellertid inte alltid fullständigt klart vad som behövs gällande planering för att öka cyklingen. Denna rapport är resultatet av en litteraturstudie om hur olika faktor kopplade till cykelplanering påverkar benägIncreased bicycling is of great importance for a sustainable transport system. This report is the result of a literature study concerning how different factors associated with bicycle planning influence the propensity to choose the bicycle for transportation. The literature study was carried out in the search engine GoogleScholar and only scientific papers, articles and books were included. Throug

Evolution of organ systems in the Crustacea: Mystacocarida and Cephalocrida in retrospect

The morphology of the internal organs of two representative species of the crustacean classes Mystacocarida, Derocheilocaris typica (Pennak & Zinn, 1943), and Cephalocarida, Hutchinsoniella macracantha (Sanders, 1955), has been studied ultrastructurally from 1990 onwards. A review of the subject offers a unique opportunity to compare and contrast the two taxa at a time when their key positions

Configuration Management - Mother's little helper for Global Agile Projects?

There are many good reasons for turning co-located projects distributed, likewise there are many good reasons for turning traditional projects agile. In both cases there are many obstacles to overcome and pitfalls to avoid and the combination of agile and distributed does not make this situation any better. In general Configuration Management works as the infrastructure of any software project and