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Acute unilateral vestibulopathy and corticosteroid treatment - A randomized placebo-controlled double-blind trial

BACKGROUND: The efficacy of corticosteroids for treating acute vestibular neuritis, or acute unilateral vestibulopathy (AUVP), remains controversial.OBJECTIVE: This study aimed to evaluate whether corticosteroids improve vestibular function and reduce symptoms in both acute and chronic phases of AUVP.METHODS: This randomized, placebo-controlled, double-blind trial included patients with AUVP (ages

Sputum culture yields after antibiotic therapy – a retrospective cohort study

ObjectiveSputum cultures can guide antibiotic therapy, particularly in severe pneumonia or when resistant pathogens are suspected. However, data on how prior and ongoing antibiotic exposure affects microbial detection are limited. This study aimed to evaluate this impact, stratified by timing and route of administration.MethodsIn- and outpatients from nine hospitals in Skåne, Sweden, who submitted

Transient dynamics of terrestrial carbon storage : Mathematical foundation and its applications

Terrestrial ecosystems have absorbed roughly 30 % of anthropogenic CO2 emissions over the past decades, but it is unclear whether this carbon (C) sink will endure into the future. Despite extensive modeling and experimental and observational studies, what fundamentally determines transient dynamics of terrestrial C storage under global change is still not very clear. Here we develop a new framewor

Optimised machine learning for time-to-event prediction in healthcare applied to timing of gastrostomy in ALS : a multi-centre, retrospective model development and validation study

Background: Amyotrophic lateral sclerosis (ALS) is invariably fatal but there are large variations in the rate of progression. The lack of predictability can make it difficult to plan clinical interventions. This includes the requirement for gastrostomy where early or late placement can adversely impact quality of life and survival. Methods: We designed a model to predict the timing of gastrostomy

Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s disease

Cell replacement therapies using human pluripotent stem cell-derived ventral midbrain (VM) dopaminergic (DA) progenitors are currently in clinical trials for treatment of Parkinson’s disease (PD). Recapitulating developmental patterning cues, such as fibroblast growth factor 8 (FGF8), secreted at the midbrain-hindbrain boundary (MHB), is critical for the in vitro production of authentic VM DA prog

Pregestational Diabetes and Duration of Active Labour Compared With Non-Diabetic Women : A Population-Based Cohort Study

Objective: To evaluate the impact of pregestational diabetes on duration of active labour (DAL) in induced and spontaneous labour and to compare caesarean section (CS) rates and indications between women with and without diabetes. Design: A population-based cohort study. Setting: Sweden. Population: 243 537 nulliparous women, registered in the Swedish Pregnancy Register, who delivered a singleton

The PARADIGM project II : The lifetimes and quenching of satellites in Milky Way-mass haloes

The abundance and star formation histories of satellites of Milky Way (MW)-like galaxies are linked to their hosts' assembly histories. To explore this connection, we use the PARADIGM suite of zoom-in hydrodynamical simulations of MW-mass haloes, evolving the same initial conditions spanning various halo assembly histories with the VINTERGATAN and IllustrisTNG models. Our VINTERGATAN simulations o

Embj.201695235.full

let‐7 regulates radial migration of new‐born neurons through positive regulation of autophagy Article let-7 regulates radial migration of new-born neurons through positive regulation of autophagy Rebecca Petri, Karolina Pircs, Marie E Jönsson, Malin Åkerblom, Per Ludvik Brattås, Thies Klussendorf & Johan Jakobsson* Abstract During adult neurogenesis, newly formed olfactory bulb (OB)

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/embj.201695235.full_.pdf - 2026-05-30

Mechanisms of Body Alignment in a Diurnal Songbird Migrant

Animals align their body in relation to different environmental cues, including spontaneous directional responses relative to the geomagnetic field known as magnetic body alignment. The biological significance of this behavior, however, remains undetermined for most taxa. In previous studies, migratory songbirds aligned their body with the cardinal directions of the geomagnetic field and their mig

Green wave for zabrze polish

Zielona Fala Dla Zabrza Strategia Zrównoważonej Mobilności Kontrola ruchu Ru ch p ie sz yc h Zielona Fala Dla ZabrZa Strategia Zrównoważonej Mobilności ZIELONA FALA DLA ZABRZA STRATEGIA ZRÓWNOWAŻONEJ MOBILNOŚCI AUTORZY: Mascha Menny, Robert Rodriguez, Daniel Ssekatawa, Žygimantas Zabieta PROMOTORZY: Mikael Backman, Lars Hansson Jeżeli nie oznaczono inaczej, wszystkie ilustracje i fotografie wykona

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/green_wave_for_zabrze_polish.pdf - 2026-05-30

Surgical and not analgesic technique affects postoperative inflammation following colorectal cancer surgery : a prospective, randomized study

AIM: Epidural analgesia reduces the surgical stress response. However, its effect on pro- and anti-inflammatory cytokines in the genesis of inflammation following major abdominal surgery remains unclear. Our main objective was to elucidate whether perioperative epidural analgesia prevents the inflammatory response following colorectal cancer surgery.METHODS: Ninety-six patients scheduled for open

Stellar encounters involving massive stars in young clusters

We model collisions between pre-main-sequence stars using a smoothed particle hydrodynamics method. Assuming that all collisions lead to simple mergers, we use derived merger cross-sections to calculate the time-scale to make a 50-M-circle dot star by collisions within the core of a stellar cluster as a function of stellar number density. We show that a 50-M-circle dot star may be produced in this

Picosecond X-ray Diffraction Studies of Bulk and Nanostructure Materials

Popular Abstract in Swedish Snabba fenomen, som inträffar efter laserexcitation, har studerats med tidsupplöst röntgendiffraktion (TXRD). I de flesta experimenten har en ljuspuls från en femtosekundlaser använts för att excitera provet, och dynamiken har undersökts med röntgenljus. Tidsupplösta röntgendiffraktionsmätningar har utförts för att studera fasta halvledarmaterial, vätskor, ferro-elektriFast phenomena occurring after laser excitation were studied using time-resolved X-ray diffraction (TXRD). In most experiments, a femtosecond laser pulse was used to excite the sample, and X-rays were used as a probe. The X-ray diffraction technique was used to study bulk semiconductor samples, molten liquids, ferro-electric domain switching in potassium dihydrogen phosphate (KDP), and strain prop

Recall and perceived naturalness of asynchronous speech and gesture

Part of the justification for an integrated view of speech and gestures ( (( is their temporal coordination. Gestures generally coincide with or precede, but rarely follow lexical affiliate (McNeill, 1992). How synchrony impacts listeners remains less explored, despite potential relevance for video communication and virtual conversational agents. ERP studies suggest that temporal alignment affects

Two years of adjuvant tamoxifen provides a survival benefit compared with no systemic treatment in premenopausal patients with primary breast cancer : Long-Term follow-up (> 25 years) of the phase III SBII:2pre trial

Purpose The aim of this study was to evaluate the long-term effect of 2 years of adjuvant tamoxifen compared with no systemic treatment (control) in premenopausal patients with breast cancer over different time periods through long-term (> 25 years) follow-up. Patients and Methods Premenopausal patients with primary breast cancer (N = 564) were randomly assigned to 2 years of tamoxifen (n = 276) o