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The economics of biobanking are intertwined with its social and scientific aspects. In this article, we illustrate this interrelationship and describe two problems that structure the discussion about the economics of biobanking. First, there is a “sustainability problem” about how to maintain biobanks in the long term. Second, and representing a partial response to the first problem, there is a “c
Objective: To examine the prevalence of dysnatraemias among children admitted for paediatric surgery before and after a change from hypotonic to isotonic intravenous maintenance fluid therapy. Design: Retrospective consecutive time series intervention study. Setting: Paediatric surgery ward at the Children's Hospital in Lund, during a 7-year period, 2010-2017. Patients: All children with a blood s
Ground improvement with lime-cement pillars is becoming increasingly common in the Nordic countries for exploitation of areas with poor stability. However, there is no non-destructive method for quality control of the ground improvement. Significant changes in the electrical properties after mixing of the binders make electrical resistivity tomography (ERT) a potential method. In connection with l
Objectives: Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, as several research works have demonstrated in a pre-clinical setting, since it is able to provide attenuation, differential phase contrast, and scattering images simultaneously. In order to translate this technique to the clinics, it has to be adapted to cover a large field-of-view within a clinic
In a controlled prospective randomized study the regimen doxorubicin (A) 40 mg/m2 + melphalan (M) 0.4 mg/kg was compared with A + M + cisplatin (C) 50 mg/m2 given every four weeks in advanced ovarian cancer, FIGO stage III or IV and with serous or anaplastic histology. From 1981 to 1983, 300 patients entered the study and 295 patients were evaluable for response, toxicity and long-term survival. A
Popular Abstract in Swedish Shusaku Endo (1923-1960) är en romersk-katolsk, japansk romanförfattare. Från 1950-1953 studerade han fransk litteratur I Lyon, Frankrike. När han återvänt från Lyon, började Endo en karriär som författare. Hans tidiga verk omfattar bl a White Men, Yellow Men (1954) Wonderful Fool (1959), The Women in the Bible (1960),Foreign Studies (1965). Denna studie analyserar hanShusaku Endo (1923-1996) is a Roman Catholic, Japanese novelist. From 1950 to 1953, he studied French literature in Lyon, France. Returning from Lyon, Endo began his career as a novelist. His early works include: White Men, Yellow Men(1954), A Wonderful Fool(1959), The Women in the Bible(1960), Foreign Studies(1965), etc. The present study analyses his work from the perspective of the inculturati
Shallow lakes have great ecological and recreational values. They are also largely affected by humans, mainly through eutrophication, and great efforts are therefore being put into the understanding of these ecosystems. The knowledge is however not complete, and more research is needed to manage these lakes in a sustainable way. The physical characteristics that are special for shallow lakes compa
The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i
Cooking fumes contain compounds that may give rise to oxidative stress and mutations when inhaled. The aim of this study was to evaluate if cooking fumes from frying of bacon induce oxidative stress by measurement of urinary 8-oxo-7,8-dihydro-2 deoxyguanosine, a marker of oxidatively damaged DNA. Three non-smoking women fried bacon for 3 h. Urine samples were taken as early morning void at the sam
Previously, radiostereometric analysis following hip revision performed using impacted morsellised allograft bone and a cemented Exeter stem has shown continuous subsidence of the stem for up to five years. It is not known whether the subsidence continues thereafter. In our study, 17 of 25 consecutive osteo-arthritic patients with aseptically loose stems who underwent first-time revision using imp
Objective: To analyze the age- and trial-specific effects of the breast cancer screening trials with mammography in Malmö, Stockholm, and Göteborg. Methods: The original trial files were linked to the Swedish Cancer and Cause of Death Registers to obtain date of breast cancer diagnosis and date and cause of death. Relative risks and 95% confidence intervals were calculated using the evaluation mod
The alteration of release of calcium ions from biological tissue by electromagnetic stimulation has bien reported by several authors (Kaczmarec and Adey 1974:, Bawin et al. 1975, 1978; Bawin and Adey 1976; Blackman et al. 1979, l980a,å; Joines and Blackman 1980, l98l; Joines et al. l98O). Bawin etal. (1975) reported that 147 MHz radiofrequency (RF) electromagnetic radiation altered the release of The 'ion cyclotron resonance hypothesis' was explored by Liboff et al. (1987) in an experiment involving incorporation of calcium-45 (n5Ca2*) in mixed human lymphocytes. The geomagnetic horizontal field component was'adjusted to 2l pT. The experiment was first performed at an amplitude of the applied oscillating field of 150 pT and a sharp minimum was obtained at the frequency of l43Hz, which corr
Svensk sammanfattningAvhandlingens syfte har varit att studera utvecklingen av en könskromosom i realtid genom att simulera dess framväxt i en hermafroditisk plattmask i laboratoriet. Jag gjorde detta genom att selektera på dels honlig fitness (fitness via ägg), dels hanlig fitness (fitness via spermier) med hjälp av en genetisk markör, som agerade som en könsbestämmande gen. Detta ska efterlikna Sex chromosome evolution in a hermaphrodite ancestor starts with the establishment of a sex-determining region (SDR). Over time, sex-specific genes, and/or sexually antagonistic alleles will become linked to the SDR. Sexually antagonistic alleles are a type of genetic variation that increases fitness for one sex while being detrimental for the other sex. Recombination arrest around the SDR and gen
Time-resolved photoluminescence (TRPL) measurements of nanowires (NWs) are often carried out on broken-off NWs in order to avoid the ensemble effects as well as substrate contribution. However, the development of NW-array solar cells could benefit from non-destructive optical characterization to allow faster feedback and further device processing. With this work, we show that different NW array an
Premise: Flower color, a key trait influencing plant–pollinator interactions, may be influenced by abiotic factors such as soil. We investigated association between pollinators, soil characteristics, and flower color variations in Digitalis purpurea across native populations in Sweden and introduced populations in Bolivia. Methods: We measured floral traits, reflectance of petals and nectar-guide
