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Non-negative matrix factorization (NMF) condenses high-dimensional data into lower-dimensional models subject to the requirement that data can only be added, never subtracted. However, the NMF problem does not have a unique solution, creating a need for additional constraints (regularization constraints) to promote informative solutions. Regularized NMF problems are more complicated than conventio
Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported.
Background The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and w
Cannulation of the papilla vateri represents an enigmatic first step in endoscopic retrograde cholangiopancreaticography (ERCP). In light of falling numbers of (diagnostic) ERCP and novel techniques, e. g. short-wire system, we were interested in the approach novice and experienced endoscopist are taking; especially, what makes a papilla difficult to cannulate and how to approach this. We devised
A bench-scale unit for the development of an enzymatic process for the bioconversion of lignocellulosics to ethanol has been used to study the recycling of waste-water streams to minimize fresh-water requirements and reduce effluent streams. Willow, after impregnation with sulphur dioxide, was steam-pretreated, enzymatically hydrolysed, and the sugars produced were fermented using S. cerevisiae. T
This paper compares the explanation for social change that are offered by three theories of rape, all of which apply a socio-cultural and a gender perspective.
This thesis seeks to investigate what factors played a role when Sweden took the decision to lessen the amount of countries it should give aid to, commonly called the land focus. It seeks to do so using foreign policy decision making theories and the rational actor model commonly assumed by those. The study is made part through the study of official materials, part through interviews with people a
Stakeholders’ participation has been recognized as a pillar for a transition toward a more sustainable society. However, there is little empirical evidence concerning the viability of participation mechanisms at large scale. This research analyzes a popular referendum process in Switzerland against a law that would have been a step toward a low-carbon society in the Canton of Fribourg. Aiming to i
Attention to the role of religious NGOs (RNGOs) in international arenas has grown in the past decade. This study explored the role of values in the policies of RNGOs involved in humanitarian aid. It sought to compare the values of RNGOs with varying levels of involvement with the Steering Committee for Humanitarian Response (SCHR) in order to determine if values may be an issue inhibiting cooperat
The upcoming changes in the demographic structure will put pressure on the healthcare system in Skåne. Tax financed hospitals with more beds, doctors, nurses and other personnel will not be the solution to cope with the upcoming demands. Increasing healthcare productivity is one way, where digital healthcare is a potential part of the solution. One of the major limitations of the digital healthcar
Today’s work environment is currently undergoing radical changes and although the aware-ness of social collaboration is growing within organizations, they still struggle with the digital transformation and thereby with the integration of Enterprise Social Network (ESN). Our study aims to investigate the role of ESN within the todays’ organizations. Specifically, it intends to build on previous res
The eminent dilemma around the relationship between the increasing world population, the need of new fuel sources and environment issues has raised great awareness in the last decades. The European Parliament has set common goals such as the reduction of the greenhouse gases by 20 % by the year of 2020, followed by the requirement of at least 10 % of the fuel has to be biofuel. An adjacent issue i
Resilience, the ability to withstand or adapt to altered conditions, gets more important as the grave effects of climate change intensify. Individuals’ capacities to respond to disasters are strongly connected to their social capital (e.g. relationships and networks). The aim of this paper is to contribute to the understanding of this connection at a neighborhood level. In the first part of this p
En av de stora utmaningarna inom den internationella handelsrätten idag är hur man ska kunna förbättra situationen för utvecklingsländer inom den internationella handeln. Denna uppsats belyser specifika undantagsregler, inom WTO-rätten, som har till ändamål att öka utvecklingsländers möjligheter att delta i den internationella handeln. Industriländer tilldelar utvecklingsländer, i enlighet med WTOOne of the current challenges within the field of international trade law is how to meet the special needs of developing countries and how to a greater extent include these countries in the world trading system. This thesis examines a particular set of exception rules that exist on behalf of developing countries. Developing countries are, in accordance with WTO law, granted different tariff prefer
Europeiska unionens (EU) huvudmålsättning är att fri rörlighet av varor, personer, tjänster och kapital ska råda inom unionen. Rättsenigheten inom EU har dock brister och det har observerats att det för en väl fungerande inre marknad hade varit behjälpligt med harmonisering av medlemsstaternas civillagstiftning. För detta ändamål har Europeiska kommissionen initierat utformningen av en gemensam reOne of the main goals of the European Union (EU) is to guarantee the free movement of goods, capital, services and people. Divergences in national contract laws are seen as an impediment to this free movement. To overcome this hurdle scholars clearly suggest that the internal market would benefit if the EU had harmonized the private law. The European Commission (EC) has therefore initiated the cre
Numerous past studies investigating the performance of hedge funds suffer from two distinct problems: unreliable and biased return data inherent in virtually all databases and the use of static asset-pricing models. Using “indexes of indexes” for our hedge fund returns, both free of biases and highly representative, we investigate which risk factors investors are exposed to and whether hedge fund
The goal of this paper is to examine various representations of the third tone in Standard Chinese, both in academic literature and textbooks for beginners, and then evaluate what consequences the choice of representation has for tone instruction. It was found that linguists primarily prefer two models, even though slight deviations were found: either a traditional approach describing the third to
In this paper we calculate the limit of the $L^1$-means of certain weighted Poisson kernels in the unit disc and show that this limit is equal to $1$. Our result is in sharp contrast to a recent result by George F\"ulep who has shown that some related limit superiors are strictly greater than $1$. Limits of this type are of interest from the point of view of approximation theory.
