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There is a need to closer characterise the molecular changes associated with progression from low to high mortality stage cutaneous T cell lymphoma. This has been challenging since there is high inter-patient heterogeneity in the genetics and transcriptomics of the malignant T cell populations. Modern technology has enabled single-cell resolution as well as spatially guided cell selection for whol

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The upcoming implementation of the ReFuelEU Aviation Initiative presents both challenges and opportunities for the European aviation sector. Starting January 2025, the EU’s aviation fuel mix must include at least 2% Sustainable Aviation Fuel (SAF), leading to higher operating costs for airlines due to SAF’s higher price than fossil kerosene. Additionally, the entire fuel supply chain will need to

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En av de stora utmaningarna inom den internationella handelsrätten idag är hur man ska kunna förbättra situationen för utvecklingsländer inom den internationella handeln. Denna uppsats belyser specifika undantagsregler, inom WTO-rätten, som har till ändamål att öka utvecklingsländers möjligheter att delta i den internationella handeln. Industriländer tilldelar utvecklingsländer, i enlighet med WTOOne of the current challenges within the field of international trade law is how to meet the special needs of developing countries and how to a greater extent include these countries in the world trading system. This thesis examines a particular set of exception rules that exist on behalf of developing countries. Developing countries are, in accordance with WTO law, granted different tariff prefer

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Europeiska unionens (EU) huvudmålsättning är att fri rörlighet av varor, personer, tjänster och kapital ska råda inom unionen. Rättsenigheten inom EU har dock brister och det har observerats att det för en väl fungerande inre marknad hade varit behjälpligt med harmonisering av medlemsstaternas civillagstiftning. För detta ändamål har Europeiska kommissionen initierat utformningen av en gemensam reOne of the main goals of the European Union (EU) is to guarantee the free movement of goods, capital, services and people. Divergences in national contract laws are seen as an impediment to this free movement. To overcome this hurdle scholars clearly suggest that the internal market would benefit if the EU had harmonized the private law. The European Commission (EC) has therefore initiated the cre

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Numerous past studies investigating the performance of hedge funds suffer from two distinct problems: unreliable and biased return data inherent in virtually all databases and the use of static asset-pricing models. Using “indexes of indexes” for our hedge fund returns, both free of biases and highly representative, we investigate which risk factors investors are exposed to and whether hedge fund

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The goal of this paper is to examine various representations of the third tone in Standard Chinese, both in academic literature and textbooks for beginners, and then evaluate what consequences the choice of representation has for tone instruction. It was found that linguists primarily prefer two models, even though slight deviations were found: either a traditional approach describing the third to

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Den fotokemiska reaktorn vid Copenhagen Centre for Atmospheric Research, Köpenhamns universitet, har i denna studie används för att bestämma nya värden på hastighetskonstanterna k(i) för reaktionen: CH3Br + OH -> produkter (i) och k(ii) för reaktionen: CH3Br + O(1D) -> produkter. (ii) Radikalerna (O(1D) och OH) framställdes i studien genom att fotolysera ozonmolekyler med UV-C-ljus. OxidationsprocThe photochemical reactor in Copenhagen Centre for Atmospheric Research, University of Copenhagen, was used to determine new values for the rate constants k(i) and of the reaction: CH3Br + OH −> products (i) and k(ii) for the reaction: CH3Br + O(1D) −> products. (ii) The radicals (O(1D) and OH) were produced by photolysis of ozone molecules with UV-C light. The oxidation process was monitored by a

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In this paper we calculate the limit of the $L^1$-means of certain weighted Poisson kernels in the unit disc and show that this limit is equal to $1$. Our result is in sharp contrast to a recent result by George F\"ulep who has shown that some related limit superiors are strictly greater than $1$. Limits of this type are of interest from the point of view of approximation theory.

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surgery (i.e. resection or liver transplantation), but only 10-20% of patients are candidates for this. In other patients, a variety of palliative treatments can be given, such as chemoembolization, radiofrequency ablation or recentlyPrimary liver cancers (i.e. hepatocellular carcinoma or cholangiocarcinoma) are worldwide some of the most frequent cancers, with rapidly fatal liver failure in a lar

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The influence of chronological ageing on the components of the cardiovascular system is of fundamental importance for understanding how hemodynamics change and the cardiovascular risk increases with age, the most important risk marker. An increase in peripheral vascular resistance associated with increased stiffness of central elastic arteries represents hallmarks of this ageing effect on the vasc

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-The atrial switch operation Mustard- or Senning operation for transposition of the great arteries (TGA) was introduced in the late 1950s and was the preferred surgery for TGA until the early 1990s. The Mustard- and Senning operation involves extensive surgery in the atria and leaves the right ventricle as the systemic ventricle. The Mustard and Senning cohort is now well into adulthood and we beg

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To validate and evaluate the psychometric properties of the ALPS-Neo, a new pain assessment scale created for the continuous evaluation of pain and stress in preterm and sick term infants.

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Ten countries have established quotas for female representation on publicly traded corporate and/or state-owned enterprise boards of directors, ranging from 33 to 50 %, with various sanctions. Fifteen other countries have introduced non-binding gender quotas in their corporate governance codes enforcing a "comply or explain" principle. Countless other countries' leaders and policy groups are in th

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BACKGROUND: Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality o

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Objective: To determine the association between radiographic osteoarthritis (OA) and pre-operative function in patients undergoing primary knee replacement. Methods: Single centre study examining pre-operative outcomes in a consecutive series of 525 patients who underwent primary knee replacement for OA between January 2006 and December 2007. Pre-operative data included: demographics, American Soc

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The purpose of this study is to present a new and improved method for translating the electrocardiographic changes of acute myocardial ischemia into a display which reflects the location and extent of the ischemic area and the associated culprit coronary artery. This method could be automated to present a graphic image of the ischemic area in a manner understandable by all levels of caregivers; fr

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This Letter presents the first study of W^{±}W^{±}jj, same-electric-charge diboson production in association with two jets, using 20.3 fb^{-1} of proton-proton collision data at sqrt[s]=8 TeV recorded by the ATLAS detector at the Large Hadron Collider. Events with two reconstructed same-charge leptons (e^{±}e^{±}, e^{±}μ^{±}, and μ^{±}μ^{±}) and two or more jets are analyzed. Production cross sect

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Designing a system for computer aided diagnosis is a complex procedure requiring an understanding of the biology of the disease, insight into hospital workflow and awareness of available technical solutions. This paper aims to show that a valuable system can be designed for diagnosing kidney lesions in children and adolescents from 99m Tc-DMSA scintigraphy images. We present the chain of analysis