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The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens
Corporate mergers and acquisitions (M&As) are prominent means for corporate strategy. In many M&As information systems (IS), integration is critical for achieving the intended goals. By integrating previous research on M&A and IS integration, we develop a six-dimensional theoretical framework for IS integration in corporate M&As. The framework is used to describe and explain IS int
Inherited retinal degenerations, collectively termed retinitis pigmentosa (RP), constitute one of the leading causes of blindness in the developed world. RP is at present untreatable and the underlying neurodegenerative mechanisms are unknown, even though the genetic causes are often established. Acetylation and deacetylation of histones, carried out by histone acetyltransferases (HATs) and histon
Given the polarized political context in Peru that was provoked by the inclusion of LGTBIQ+ identities in the official school curriculum, this study analyzes the meanings that students of pedagogy in Lima ascribe to tolerance and respect towards gay and lesbian people, and how these meanings inform their pedagogical practices. Based on two focus groups and eight individual interviews grounded in s
Through research and interviews with several experts and stakeholders during the study visit in Zabrze, Poland, the main sources of air pollution in Zabrze and potential areas of intervention were identified. The project focused on residential heating in Zabrze, as coal based heating systems were identified as the main contributor to air pollution in the city. An alternative heating system scenari
Mitochondrial creatine kinase (Mi-CK) isoenzymes, in contrast to cytosolic CKs, form octameric molecules composed of four stable dimers. Octamers and dimers are interconvertible. Removal of the N-terminal pentapeptide of chicken cardiac Mi-CK (Mib-CK) by limited proteolysis drastically destabilized the octamer. The role of the charged amino acids within the N-terminal heptapeptide was studied in d
Specialized epitope tags are widely used for detecting, manipulating or purifying proteins, but often their versatility is limited. Here, we introduce the ALFA-tag, a rationally designed epitope tag that serves a remarkably broad spectrum of applications in life sciences while outperforming established tags like the HA-, FLAG®- or myc-tag. The ALFA-tag forms a small and stable α-helix that is func
Laminins are basement membrane components that regulate a plethora of biological processes. Despite decades of research, the exact roles of laminins in different tissues and in organogenesis remain to be elucidated. Here, we investigated the function of laminin γ1 chain in heart, lung and other tissues by generating a mouse that lacks laminin γ1 in cells expressing SM22α (Tagln) (LMγ1 flox/SM22α C
1 (Information in English below) Hej, Här kommer årets sommarbrev med hälsningar från oss på Saco-S vid Göteborgs universitet. Vi önskar dig en fantastisk sommar och tid för ledighet. Med detta brev vill vi informera om semester och löneenkäten. Men först vill vi ta upp en viktig fråga från årsmötet. Saco-S är en partsgemensam förhandlingsorganisation som företräder statligt anställda akademiker.
Popular Abstract in English These days we hear a lot about sustainability and most of us try to live in a more sustainable way. We use less water and energy, we sort our household waste and we prefer to consume products that are produced with less negative human impact. However, when it comes to our own excreta we definitely think of it as waste. And we are glad enough that wastewater treatment syEutrophication or the nutrient enrichment of water bodies, typically by nitrogen and phosphorus has adversely affected the aquatic life and the quality of water. Governments have been forced to take actions in order to reduce the release of these nutrients into the environment. To date the main global effort has been to remove such nutrients at source. However, with an increase in awareness of the
