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This research examines the impact of digitalization on Sales and Operations Planning (S&OP) and its broader influence on supply chain performance. By adopting digital technologies, companies can streamline decision-making processes, reduce manual efforts, and enhance operational efficiency. The study aims to address the insufficient understanding of how the integration of digital technologies
Studier av palaeostormfloder ger bakgrund till inom vilka intevall stormar av olika storlek förväntas återkomma och träffa olika områden. Denna information kan användas vid modellering, riskbedömning och stadsplanering. Genom att använda de marina ekvationerna av Nittrouer och Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continental sheStudies of palaeostorm surges provides background into at what frequencies storms of different magnitudes are expected to return and hit different areas. This information can be used when modelling, doing risk assesments and city planing. Using the marine equations of Nittrouer and Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continenta
The detailed dynamic modelling, simulation and optimisation of a batch distillation process at Bayer AG is presented. The model considers a mixture of 10 components separated in a 40 tray column. Simulations performed in the process modelling tool gPROMS proved that the model gives a very accurate description of the process behaviour. To increase the profit of the process an optimisation of the op
Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of
China is a mega-diversity country with abundant natural resources, and the richness of these resources is demonstrated to be relevant with the local people’s historical interactions between biophysical and sociocultural systems. If we are to maintain biodiversity and strike a balance between human well-being and ecosystem service, it is important to incorporate the local people and their tradition
This investigation concerns written output produced by Swedish learners of English as a second language (L2) and French as a third language (L3). The analysed texts were rated according to the Common European Framework of Reference for Languages (CEFR), which is a widespread and language-independent document commonly used to assess communicative competence based on six main proficiency levels (A1,
Ground source heat pump systems, operating in conjunction with vertical ground heat exchangers, will play a key role in decarbonising heating and cooling of buildings. Design of traditional borehole heat exchangers relies on tools which implement routine analytical relationships between heat transferred and the temperature change in the ground and circulating thermal fluid. However, for novel pile
Recently, a haplotype of three single-nucleotide polymorphisms (tri-SNP) in intron 1 of the HLA-DRA1 gene was found to be strongly associated with type 1 diabetes risk in HLA-DR3/3 individuals. The tri-SNP reportedly function as “expression quantitative trait loci,” modulating HLA-DR and -DQ expression. The aim was to investigate HLA-DRA1 tri-SNPs in relation to extended HLA class II haplotypes an
In developing countries, the use of mathematical models in hydrological forecasting is increasing, making for optimal planning and management of water resources systems. Such application, however, faces different problems. One of these problems is that computers may not be available. Even if they are available, computer time is expensive. Hence, there is a need for simple models which can be run o
Background: The existing association between skin disease and psychiatric comorbidity has gained attention during the last decades. Stress and mental illness can directly or indirectly affect skin disease, while dermatological conditions, known to impair life quality and mental well-being, can promote psychiatric conditions. Objectives: The aim of this study was to assess the risk of developing ps
PURPOSE The ESPAC4 trial showed that adjuvant chemotherapy with gemcitabine plus capecitabine (GemCap) produced longer overall survival (OS) than gemcitabine monotherapy. Subsequently, the PRODIGE24-CCTG PA.6 trial showed even longer survival for modified fluorouracil, folinic acid, irinotecan, and oxaliplatin (mFOLFIRINOX) than gemcitabine but had more restrictive eligibility criteria. Our aim wa
The advent of diffraction-limited storage rings (DLSRs) has boosted the brilliance or coherent flux by one to two orders of magnitude with respect to the previous generation. One consequence of this brilliance enhancement is an increase in the flux density or number of photons per unit of area and time, which opens new possibilities for the spatiotemporal resolution of X-ray imaging techniques. Th
