Filtyp
Här annonserar vi kontinuerligt nya förslag till examensarbeten på avancerad nivå (GEOR02, 45 hp). De senaste förslagen ligger överst och gamla tas bort efter hand som de blir inaktuella. Kontakta huvudhandledaren om du är intresserad. Du är dessutom alltid välkommen att utifrån dina egna intressen diskutera olika möjligheter med dina lärare. Här kan du se exempel på tidigare masterarbeten. Notera
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
The biothiols sensing mechanism of (E)-7-(diethylamino)-3-(2-nitrovinyl)-2H-chromen-2-one (DCO) has been investigated using the density functional theory (DFT) and time-dependent DFT methods. The theoretical results indicate that the excited-state intermolecular hydrogen bonding (H-B) plays an important role for the biothiols sensing mechanism of the fluorescence sensor DCO. Multiple H-B interacti
Haematopoietic stem cells (HSCs) are important target cells for gene therapy of blood disorders due to their pluripotency and ability to reconstitute haematopoiesis following myeloablation and transplantation. HSCs can 'self-renew' and generate new stem cells. Genetically modified stem cells are therefore expected to last a lifetime in the recipient following blood and marrow transplantation, and
To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz
The Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
This research presents the modeling of the anaerobic digestion of cane-molasses vinasse, hereby extending the Anaerobic Digestion Model No. 1 with sulfate reduction for a very high strength and sulfate rich wastewater. Based on a sensitivity analysis, four parameters of the original ADM1 and all sulfate reduction parameters were calibrated. Although some deviations were observed between model pred
We summarize here the results of a major eight-year investigation of the extraordinarily detailed UV spectrum of the sharp-lined, nonmagnetic, main-sequence, chemically peculiar star chi Lupi (B9.5p HgMn + A2 Vm). The UV observations are composed of 345 Angstrom of the spectrum acquired with the Goddard High Resolution Spectrograph (GHRS) on board the Hubble Space Telescope at an average resolutio
Semiotics is generally conceived as being opposed to phenomenology, but such an opposition can only result from taking too much for granted, about both phenomenology and semiotics. While recognising that semiotics and phenomenology are historically different traditions, the present essay suggests that these traditions have a lot in common and that their very differences may give rise to fruitful p
Interviews where photographs taken by the respondent are used in order to stimulate the conversation and to gain rich empirical material are increasingly employed by researchers. The ubiquitous use of mobile cameras and digital platforms such as Instagram has made it easier for the researcher as well as for the interviewees to take and share photographs. The limitations of participatory visual met
