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The Gram-negative bacterial outer membrane contains lipopolysaccharide, which potently stimulates the mammalian innate immune response. This involves a relay of specialized complexes culminating in transfer of lipopolysaccharide from CD14 to Toll-like receptor 4 (TLR4) and its co-receptor MD-2 on the cell surface, leading to activation of downstream inflammatory responses. In this study we develop
Neural stem cell lines represent a homogeneous source of cells for genetic, developmental, and gene transfer and repair studies in the nervous system. Since both gene transfer of neurotrophic factors and cell replacement strategies are of immediate interest for therapeutical purposes, we have generated BDNF-secreting neural stem cell lines and investigated to what extent different endogenous level
The purpose of this thesis is to analyse how the European Union constructs and articulates peace within its official discourse in relation to the conflict between Russia and Ukraine in 2014, 2021 and 2025. The European Union has long presented peace as a central part of its political identity, values and external role. However, political actors, such as the European Union, frequently invoke peace
Prel.Schema MVEN015 - Klimatförändringen - vetenskap och samhälle Höstterminen 2019 OBS Alla starttider med kvart utom tentamen! Kurstid: Kursansvarig: Niklas Vareman Lärare: NBO Niklas Boke Olén JS Johannes Stripple NV Niklas Vareman JAO Johanna Alkan Olsson DH David Harnesk MR Markku Rummukainen Salar: Mossen Ö/V, Kärret Ö/V, Röda rummet Ekologihuset Sölvegatan 37 Lund, se karta över kurssalar L
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven15_schema_ht19_v2.pdf - 2026-07-18
Accurate labels are critical for deriving robust machine learning models. Labels are used to train supervised learning models and to evaluate most machine learning paradigms. In this paper, we model the accuracy and cost of a common weak labeling process where annotators assign presence or absence labels to fixed-length data segments for a given event class. The annotator labels a segment as "pres
Background: Pain is a debilitating symptom of rheumatoid arthritis (RA), caused by joint inflammation and cartilage and bone destruction. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat pain and inflammation in RA, but are not disease-modifying and do not prevent joint destruction when administered alone. KBPs (Key Bioscience peptides) are synthetic peptides based on salmon calcitoBackground: Pain is a debilitating symptom of rheumatoid arthritis (RA), caused by joint inflammation and cartilage and bone destruction. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat pain and inflammation in RA, but are not disease-modifying and do not prevent joint destruction when administered alone. KBPs (Key Bioscience peptides) are synthetic peptides based on salmon calcito
Background: The molecular pathways linking short and long sleep duration with incident diabetes mellitus (iDM) and incident coronary heart disease (iCHD) are not known. We aimed to identify circulating protein patterns associated with sleep duration and test their impact on incident cardiometabolic disease. Methods: We assessed sleep duration and measured 78 plasma proteins among 3336 participants
