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Objectives. To study the correlation between Sunnybrook and House-Brackmann facial grading systems at different time points during the course of peripheral facial palsy. Study Design. Prospective multicenter trial. Setting. Seventeen otorhinolaryngological centers. Subjects and Methods. Data are part of the Scandinavian Bell's palsy study. The facial function of 1920 patients with peripheral facia

In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper

Background: Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will ultimately develop in approximately 50% of patients, with the liver being the most common site for metastases. The median survival for patients with liver metastases is between 6 and 12 months, and no treatment has in randomized trials eve

Background: In the present study the effect of a workplace-oriented intervention for persons on long-term sick leave for clinical burnout, aimed at facilitating return to work (RTW) by job-person match through patient-supervisor communication, was evaluated. We hypothesised that the intervention group would show a more successful RTW than a control group. Methods: In a prospective controlled study

The main goal of this thesis is to investigate the properties and prospects of the new digital currency, Bitcoin. How is it structured and is there a possibility of it having a substantial impact on the financial sector or today’s monetary systems? Through macroeconomic theory, financial models and academic writing we will explain the fundamentals of money, how the Bitcoin network functions and in

Abstract Metal oxide semiconductor (MOS) capacitor was fabricated on the InGaAs substrate with Al2O3/HfO2 gate oxide. InGaAs is one of the promising candidates for advanced applications which require the lower power supply and high frequency. The high-k films (Al2O3/HfO2) were formed by atomic layer deposition (ALD) as an alternative to silicon dioxide (SiO2) to proceed the scaling of oxide to low

The immune cell component of the tumor microenvironment is an important modulator of tumor progression. In patients with breast cancer, tumor-infiltrating lymphocytes (TILs) and tertiary lymphoid structures (TLS) represent core aspects of anti-tumor immunity, both increasingly recognized for clinical relevance. In this study, we evaluated immune-related histology features using whole slide H&E

At a time when artificial intelligence is developing rapidly, this thesis explores the issue of copyright infringement of AI-generated artworks. This study aims to analyze the legal complexities brought about by the increasingly widespread application of artificial intelligence in the creation of original artworks, with a special focus on the protection of creators’ rights and intellectual propert

Protection of humanitarian aid workers (HAWs) is a challenging task. There are various reports on the topic where much research seems to focus on traditional physical attacks and intentional violence against HAWs (security) rather than the accidental event risks (safety) or discussing it separately. These risks are usually defined by the organization’s security risk management holding the power in

Research question: In what way has Swedbank applied accounting communication surrounding the money laundering scandal and how has the communication developed and changed over time along the course of the event? Purpose: The purpose of the study was to examine how Swedbank applied accounting communication in order to manage and rebuild their reputation in connection to the money laundering scandal

As Climate Change increases the frequency and severity of wildfires in British Columbia, communities at the Wildland Urban Interface face escalating risks. This thesis explores the challenges and opportunities of community engagement in wildfire management in the city of Kamloops, one of the most fire-prone urban areas in British Columbia. Employing a single-case study design, the research is base

The aim of this thesis is to investigate the determinants of the retirement decisions in Sweden by using qualitative micro data from The Survey on Health and Retirement in probit models. The models investigate the change in job status between the first survey wave in year 2004 and the second survey wave in year 2006/2007 by adding background variables measured in years 2004. The study show that de

In Swedish society the demands on the adult literacy-rate are very high and due to migration Sweden has gotten a number of adult illiterates. This essay examines what possibilities an illiterate has to learn to write and read and receive possibilities to integrate with Swedish society and become independent. People who can’t read and write and migrates to Sweden shall not just learn the Swedish la

Animal species differ considerably in their ability to fight off infections. Finding the genetic basis of these differences is not easy, as the immune response is comprised of a complex network of proteins that interact with one another to defend the body against infection. Here, we used population- and comparative genomics to study the evolutionary forces acting on the innate immune system in nat

Information processing by traditional, serial electronic processors consumes an ever-increasing part of the global electricity supply. An alternative, highly energy efficient, parallel computing paradigm is network-based biocomputation (NBC). In NBC a given combinatorial problem is encoded into a nanofabricated, modular network. Parallel exploration of the network by a very large number of indepen

Evidence on long-term multigenerational dynamics is often inadequate as large datasets with multiple generations remain very uncommon. We posit that genealogical records can offer a valuable alternative. Rather than exploring the intergenerational transmission of socioeconomic status, we rely on birth and death dates of eighteenth and nineteenth century settlers in South Africa's Cape Colony to es

This study investigates possible structural changes of an intrinsically disordered protein (IDP) when it adsorbs to a solid surface. Experiments on IDPs primarily result in ensemble averages due to their high dynamics. Therefore, molecular dynamics (MD) simulations are crucial for obtaining more detailed information on the atomistic and molecular levels. An evaluation of seven different force

Automated detection of cell nuclei in fluorescence microscopy images is a key task in bioimage analysis. It is essential for most types of microscopy-based high-throughput drug and genomic screening and is often required in smaller scale experiments as well. To develop and evaluate algorithms and neural networks that perform instance or semantic segmentation for detecting nuclei, high quality anno