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BACKGROUND: Patterns of spatial variation in discrete phenotypic traits can be used to draw inferences about the adaptive significance of traits and evolutionary processes, especially when compared to patterns of neutral genetic variation. Population divergence in adaptive traits such as color morphs can be influenced by both local ecology and stochastic factors such as genetic drift or founder ev
Two searches for supersymmetric particles in final states containing a same-flavour opposite-sign lepton pair, jets and large missing transverse momentum are presented. The proton-proton collision data used in these searches were collected at a centre-of-mass energy root s = 8TeV by the ATLAS detector at the Large Hadron Collider and corresponds to an integrated luminosity of 20.3 fb(-1). Two lept
Total levels of circulating prostate-specific antigen (tPSA) are strongly associated with prostate cancer (PCa) risk and outcome but benign prostate disease is the most frequent cause of a moderately elevated PSA level. Free PSA (fPSA) forms are independently associated with PCa risk and contribute modest diagnostic enhancements above and beyond tPSA alone. We developed an immunoassay for fPSA sub
A method for the quantitative determination of non-steroidal anti-inflammatory drugs (NSAIDs) in sewage sludge was developed and validated. The target compounds were extracted using pressurized hot water extraction (PHWE) and then purified and preconcentrated by three-phase hollow fiber liquid phase microextraction (HF-LPME) followed by LC-ESI-MS analysis. The PHWE was optimized with regard to the
PHENIX has measured the e(+)e(-) pair continuum in root s(NN) = 200 GeV Au+Au and p+p collisions over a wide range of mass and transverse momenta. The e(+)e(-) yield is compared to the expectations from hadronic sources, based on PHENIX measurements. In the intermediate-mass region, between the masses of the phi and the J/psi meson, the yield is consistent with expectations from correlated c (c) o
Water is arguably the world’s most valuable endangered resource, the management of which has been subject of contentious debate that in recent years has gained growing political, economic and media attention. This study intends to make use of that momentum by constructing a framework for quantifying global water crisis risk that is applied to assess both the EU’s share of such risk and the success
In this thesis an optimization of a previously performed inclusive search for beyond Standard Model Physics in same-sign di-lepton final states is performed, but tuned for a doubly-charged Higgs boson decaying to same-sign di-muons. The doubly-charged Higgs boson is a proposed fundamental particle whose existence would provide evidence for theoretical extensions of the Standard Model (SM) of parti
The purpose of this thesis was to examine climate related human mobility in the Southern Africa Development Community (SADC). The adverse effect of climate change in SADC is mainly linked to increasing rainfall variability and a higher frequency or intensity of floods and droughts. These effects are a major challenge for human security. Climate change has emerged as one of the most pressing, unres
Soil as a fundamental, conditionally renewable natural resource is increasingly under threat from unsustainable farming practices in a changing environment. In Hungary, expansive areas of land are susceptible to soil degradation, while only a small percentage of farmers currently applies soil conservation practices (SCPs). Degraded soils have an impact on food production, climate adaptation, clima
Objectives: Romania joined to European Union (EU) in 2007. Consequently, the number of EU citizens of Roma descent increased in Sweden as the movement of freedom was granted. This study attempts to understand the conceptualisation and reason for underreporting hate crimes in Malmö, Sweden. Methods: Qualitative data collection methods of semi-structured interview and participant observation were e
BACKGROUND: Spinal cord injury (SCI) may, and often does, profoundly reshape daily life, altering physical abilities, social roles, and personal identities. While assistive technologies, including assistive robotics, are often framed as solutions to re-establish independence, their adoption is shaped by practical, emotional, and social considerations as well as functional qualities. Individuals wi
In recent years, the drawbacks of parallel systems in Disaster Risk Reduction (DRR) and Climate Change Adaptation (CCA) have been acknowledged in professional and academic communities, where the need for integration of the two fields in connection to development has been stressed. In this regard, the concept of resilience as an antithesis of risks has also been considered. In this study, a scoping
Gruv- och ballastindustrin utgör en mycket viktig sektor i den svenska ekonomin. Där gruvindustrin operar på den globala arenan medan sten branschen operar på regional/lokal basis. Efterfrågan av metaller- och byggnadsmaterial har ökat under det senaste decenniet och mängden fasta mineraler och stenar som tas ut ur jordskorpan är nästan 80 miljarder ton per år, med ballast som den största delen.DeThe mining and quarrying industries represent a highly important sector of the Swedish economy. The mining industry operates globally, whereas the quarrying industry operates on a regional/local basis. Demands for metal and construction aggregates have increased over the last decade, and almost 80 billion tons of solid minerals and rocks are extracted from the earth’s crust each year. Construction
Affibody molecules, small (7 kDa) scaffold proteins, are a promising class of probes for radionuclide molecular imaging. Radiolabeling of Affibody molecules with the positron-emitting nuclide 68Ga would permit the use of positron emission tomography (PET), providing better resolution, sensitivity, and quantification accuracy than single-photon emission computed tomography (SPECT). The synthetic an
Astrocytes are one of the major cell types in the central nervous system and are indispensable for brain development and function. The human brain and human astrocytes have unique structures and functions that are not present in other animal species. Studies of fundamental astrocyte biology in humans and their role in neurological disease have been hindered by shortage of native human astrocytes f
The objective was to increase understanding of how knee-injured people make sense of using the Motor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) training intervention. This model integrates structured psychological skills training into existing care-as-usual (CaU) rehabilitation protocols. To better understand patients' lived experiences of MOTIFS, it was necessary to understand those
Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with waist circumference (WC) and waist-to-hip ratio (WHR) adjusted for BMI (WCadjBMI and WHRadjBMI), but it remains unclear whether these SNPs relate to change in WCadjBMI or WHRadjBMI with lifestyle intervention for weight loss. We hypothesized that polygenic scores (PS) comprised of 59 SNPs previou
A combination of searches for Higgs boson decays into a visible photon and a massless dark photon (H → γγd) is presented using 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The observed (expected) 95% confidence level upper limit on the Standard Model Higgs boson decay branching ratio is determined to
BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of hospitalization worldwide. Bed rest with low levels of physical activity is common during periods of hospitalization and leads to functional decline as well as increased risk of complications. The aim of this study is to assess the effect of supervised physical training during hospitalization with CAP compared with standard usual
