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Cationic-anionic surfactant mixtures can form aqueous two-phase systems. Such aqueous surfactant two-phase systems (ASTP systems) can be used for separation and purification of biomaterials. In this work we investigated the phase behavior and the partitioning of BSA and lysozyme in the ASTP system formed by mixtures of dodecyltriethylammonium bromide and sodium dodecylsulfate (SDS). The pseudo ter
The dust detector system onboard Galileo has recoding dust impacts incircumjovian space since the spacecraft was injected into a bound orbitabout Jupiter in December 1995. This is the sixth in a series of papersdedicated to presenting Galileo and Ulysses dust data. We present datafrom the Galileo dust instrument for the period January to December 1996when the spacecraft completed four orbits about
OBJECTIVE: Previous studies have shown possible neuroendocrine effects of GH. In the present study we investigated the incidence of mental disorders and the prevalence of mental distress and cognitive dysfunction in hypopituitary women with untreated GH deficiency compared to population-based controls.DESIGN AND PATIENTS: Thirty-three hypopituitary women with a median age of 64 years (range 39--77
Popular Abstract in Swedish Avhandlingen består av fem fristående uppsatser som utnyttjar tidsserieanalys för studerande av några olika makroekonomiska frågor. I kapitel två, tre och fyra används s.k. vektorautoregressiva (VAR) modeller för att studera privat konsumtionsbeteende i Sverige. Enligt den permanenta inkomst hypotesen väljer individerna sin konsumtion med hänsyn till sin långsiktiga ellAdvances in time series analysis during the last two decades have stimulated research in a number of areas in macroeconomics. This thesis is a compilation of five essays using cointegrated vector autoregressive (VAR) models, unit root tests and regime switching models to investigate the behavior of private consumption, public debt and the real exchange rate. Chapter two explores the empirical evi
The effects on wood of simultaneous mechanical and moisture loading are studied. In order to clarify the mechano-sorptive behaviour of wood, a review of different phenomena presented in the literature is included. Compressive tests have been performed on spruce. The tests have been performed with both constant load and varying load. The humidity has been varied during the tests. The properties of
Nausea and emesis are common side effects of opioid drugs administered for pain relief in cancer patients. The aim of this study was to compare the anti-emetic efficacy and safety of ondansetron, placebo and metoclopramide in the treatment of opioid-induced nausea and emesis (OIE) in cancer patients. This was a multinational, multicentre, double-blind, parallel group study in which cancer patients
Pharmacy-grade exogenous lung surfactant preparations of bovine and porcine origin, dispersed in physiological electrolyte solution have been studied. The organization and dynamics at the air/water interface at physiological temperature was analysed by neutron reflection. The results show that a well-defined surface phase is formed, consisting of a multilayer structure of lipid/protein bilayers al
Popular Abstract in Swedish Prostatacancer är den bland män vanligast förekommande cancerformen i Sverige. Under 2003 diagnostiserades 9882 nya fall. Sjukdomen drabbar framför allt äldre individer; många män är 70 år gamla eller äldre när de får diagnosen. Sjukdomsförloppet kan vara mycket varierande. Hos många är tumörtillväxten långsam, men sjukdomen kan också utvecklas snabbt. Många patienter lConcentrations of prostate-specific antigen (PSA) and human kallikrein 2 (hK2) were investigated in blood samples that had been obtained from men who were diagnosed with prostate cancer (PCa) decades later. The studies were based on a cohort comprising 22,444 men who, in 1974?1986, were early middle aged and represented a non-PCa-screened population. The results clearly demonstrate a very strong c
Popular Abstract in Swedish Kritiskt sjuka patienter på intensivvårdsavdelningar (IVA) har ofta störningar i blodets levringsförmåga (koagulation). Kliniska tecken som blodpropp (djup ventrombos eller blodpropp i lungorna) och/eller blödning kan vara resultatet av aktivering och konsumtion av koagulationsfaktorer och koagulationshämmare. Disseminerad intravaskulär koagulation (DIC, som är en samtiCritically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma
Migratory strategies of birds require complex orientation mechanisms, morphological adaptations, and life-history adjustments. From an evolutionary perspective, it is important to know how fast this complex combination of traits can evolve. We analyzed mitochondrial control-region DNA sequences in 241 blackcaps (Sylvia atricapilla) from 12 populations with different migratory behaviors. The sample
Endoscopic sinus surgery (ESS) is today a common method for the treatment of chronic rhinosinusitis. Assessment of the results has been based mainly upon subjective evaluation, and only a few reports present objective measurements, In the present study, the 133-xenon washout technique was used for preoperative and postoperative evaluation of paranasal sinus ventilation in 12 patients selected for
Popular Abstract in Swedish Den huvudsakliga hämmande signalsubstansen i hjärnan är GABA (gamma-aminobutyric acid, gamma-aminosmörsyra). GABA finns i ungefär hälften av alla nervceller i hjärnan och alla nervceller i hjärnan antas ha receptorer som binder GABA. Om man tänker på alla de normala neurologiska funktioner samt rubbningar där GABA är involverat är det inte svårt att förstå GABA:s oerhörInhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). In this thesis the functional and pharmacological properties of GABAA receptors expressed in brain slices or i
Multipotent stem/progenitor cells derived from human first trimester forebrain can be expanded as free-floating aggregates, so called neurospheres. These cells can differentiate into neurons, astrocytes and oligodendrocytes. In vitro differentiation protocols normally yield γ-aminobutyric acid-immunoreactive neurons, whereas only few tyrosine hydroxylase (TH) expressing neurons are found. The pres
The immunosuppressant cyclosporin A (CsA) has been shown to have neuroprotective action. The inhibition of both calcineurin activation and mitochondrial permeability transition pore (mtPTP) opening are considered the primary neuroprotective mechanisms of CsA. Here we have evaluated the effect of CsA on significantly reducing infarct size induced by transient middle cerebral artery occlusion (MCAO)
Distal tephra horizons, particularly within lacustrine sequences, are increasingly being used as time-synchronous marker horizons within palaeoclimatic and palaeoenvironmental investigations. As sedimentary features marking the presence of these so-called cryptotephras are absent to the naked eye, it is of some importance that the stratigraphic position representing primary airfall, and likewise t
Degradation of bovine nasal cartilage induced by interleukin-1 (IL-1) was used to study catabolic events in the tissue over 16 days. Culture medium was fractionated by two-dimensional electrophoresis (isoelectric focusing and SDS-PAGE). Identification of components by peptide mass fingerprinting revealed released fragments representing the NC4 domain of the type IX collagen {alpha}1 chain at days
Popular Abstract in Swedish VIKTEN AV HETEROGENA JORDBRUKSMILJÖER FÖR GRÅSPARVEN Under de senaste 40 åren har vårt odlingslandskap genomgått kraftiga strukturella förändringar som en konsekvens av att jordbruket har intensifierats och effektiviserats. Dessa förändringar har möjliggjort en nödvändig, ökad produktion av spannmål och andra grödor men samtidigt har det haft förödande konsekvenser på dStrong declines of European farmland birds in recent decades are assumed to be caused by decreased food availability resulting from agricultural intensification and concomitant loss of farmland heterogeneity. One of the species suffering particularly strong declines in NW European countries is the house sparrow. In this thesis I investigated the importance of farmland land-use on house sparrow eco
The Swedish Knee Arthroplasty Register (SKAR) was initiated in 1975 to prospectively follow patients operated on with knee arthroplasty. With revisions utilized as the end-point in survival analyses, it is of importance that all revisions of included patients are reported. To validate if revision status was correctly recorded, a postal survey was made among all living patients, registered as opera
The six chapters of this study approach the work of Cornelis Vreeswijk from different perspectives with an emphasis on the motifs, poetic technique, and intertextuality of individual songs amd Iyrical texts. Vreeswijks s work is interpreted in the context of contemporary history and debate, the cultural tradition to which it belongs and important events in the author's life. The first chapter foc
