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Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. The aim of this thesis was to analyze DNA methyla

ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat

Laccase, the phenol oxidizing enzyme, was first described towards the end of the 19th century from the wound sap of the lacquer tree Rhus vernicifera. The enzyme has the widest distribution in nature among the multicopper oxidases. It catalyzes single electron transfer oxidation in the presence of molecular oxygen producing water as by-product. Based on these highly desired mild oxidising conditio

The research work described in this thesis is concerned with the modification of oxide surfaces, as reflected by its title. The surfaces and their modification have been studied using a range of experimental surface characterization tools, in particular x-ray photoelectron spectroscopy (XPS), fluorescence microscopy, scanning electron microscopy, atomic force microscopy, and scanning tunneling mic

Popular Abstract in English The catalytic and electrochemical properties of tryptophan repressor-binding protein (WrbA), pyranose dehydrogenase (PDH), cellobiose dehydrogenase (CDH) and glucose dehydrogenase (GDH) on carbon electrodes were investigated using cyclic voltammetry and flow injection amperometry to construct biosensors and biofuel cell (BFC) anodes. WrbA has a catalytic FMN-containing The catalytic and electrochemical properties of tryptophan repressor-binding protein (WrbA), pyranose dehydrogenase (PDH), cellobiose dehydrogenase (CDH) and glucose dehydrogenase (GDH) on carbon electrodes were investigated using cyclic voltammetry and flow injection amperometry to construct biosensors and biofuel cell (BFC) anodes. WrbA has a catalytic FMN-containing domain whereas both PDH and

https://www.botan.lu.se/bioblitz-botanical-garden - 2026-07-21

An impact at Chicxulub, Mexico, occurred 66 million years ago, producing a global stratigraphic layer that marks the boundary between the Cretaceous and Paleogene eras. That layer contains elevated concentrations of platinum-group elements, including ruthenium. We measured ruthenium isotopes in samples taken from three Cretaceous-Paleogene boundary sites, five other impacts that occurred between 3

Choosing to continue working after retirement eligibility can attract both negative and positive sentiments from the general public. Studies examining the motivations of older workers have so far been conducted in times of relative social and economic stability. However, little is known about what it means for older workers to work during a lockdown or pandemic situation. The present longitudinal

2023-09-29ContentsData from the Social Insurance Agency (Försäkringskassan) on disability pension (DP), number of sick-leave days and periods, sick-leave diagnoses. The individuals were followed from the MDC baseline screening date until they got disability pension or long-term sick-leave, emigrated, died, turned 65 years of age, or until December 31 2005 when the study ended.Lines: 7 086Variables

https://www.malmo-kohorter.lu.se/malmo-kost-cancer-mkc/datainsamling-mkc/mdc-neck-shoulder-social-insurance-agency - 2026-07-21

Lägg till titel FÖRSÄTTSSIDA STYRDOKUMENT Kvalitetspolicy för Lunds universitet Typ av styrdokument: Policy Definition av typen av styrdokument: En policy uttrycker ledningens övergripande viljeriktning eller värden som ska beaktas inom det område policyn omfattar och sätter ramarna för ett visst handlande och utgör en stark rekommendation om ett visst handlingssätt. Beslutsfattare: Universitetsst

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-11/Kvalitetspolicy%20fo%CC%88r%20Lunds%20universitet.pdf - 2026-07-23

The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. The TRP Ankyrin 1 (TRPA1) i

Parkinson’s disease is a progressive neurodegenerative disorder. Since the motor manifestations of the disease is associated with the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta, cell replacement therapy is a promising approach for treatment. Although several different cell types have been used in clinical trials, with the recent findings of somatic cell nuclear tr