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Genome-wide association scans in type 2 diabetes (T2D) have identified a risk variant, rs13266634 (Arg325Trp), in SLC30A8 on chromosome 8. SLC30A8 encodes a beta-cell specific zinc-ion transporter and rs13266634 has been shown to affect insulin secretion. Recently, autoantibodies for Slc30A8 with high predictive value were demonstrated in individuals with type 1 diabetes (T1 D), making this gene a
Cleavage of P=Se bonds occurs readily in the room-temperature treatment of [Os-3(CO) (10)(MeCN)(2)] with Ph3P=Se to give three new compounds, [Os-3(mu(3)-Se)(2)(CO)(8)(PPh3)] (2), [Os-3(mu(3)-Se)( mu(3)-CO)(CO)(7)(PPh3)(2)] (5) and [Os3(mu-OH)(2)(CO)(8)(PPh3)(2)] (6), respectively, and three known compounds, [Os-3(mu(3)-Se)(2)(CO)(9)] (1), [Os-3(mu(3)-Se)(mu-CO)(2)(CO)(7)(PPh3)] (3), and 1,2-[Os-3
District heating is well expanded in the residential areas in Sweden, although not in detached house areas. Increased environmental concerns as well as steadily increasing electricity and oil prices make the detached houses sector a potential market for the district heating companies. District heating in low heat density areas is economically challenging for mainly two reasons: Firstly, constructi
Popular Abstract in Swedish Immunsystemet skyddar oss mot de patogener (t ex bakterier eller virus) som vi dagligen utsätts för. Det består av flera olika samtidigt verkande system. De enklare består av vår hud och de olika slemhinnor som finns till exempel i halsen och i tarmsystemet. Vidare finns det olika typer av celler och blodproteiner som kan skydda oss mot många infektioner. Det mest utvecThis thesis focuses on molecular changes occuring during terminal B cell differentiation as well as on somatic hypermutation and the generation and maintenance of B cell memory. During T cell dependent immune responses the average affinity for the eliciting antigen increases with time. This affinity maturation is generated by somatic hypermutation and selection for B cells carrying a high-affinty
Popular Abstract in English Animal flight has always intrigued people, and different aspects of animal flight have therefore widely been studied by biologists, physicists and engineers. At least to me, the aspect concerning the aerodynamics of animal flight in particular is very interesting because of the complex temporal varying wake dynamics as a result of continually wing morphing in flapping fThe efficiency and performance of a flying animal is directly related to the aerodynamics around its body and flapping wings. Here, I have developed methods for quantifying the wake dynamics around a flying animal. The results are used to estimate the aerodynamic performance of flapping flight. Using these methods, I have studied flight of the Pied Flycatcher (Ficedula hypoleuca), the Pallas’ Long
Microalgae enhance the removal of nutrients, organic contaminants, heavy metals, and pathogens from domestic wastewater and furnish an interesting raw material for the production of high-value chemicals (algae metabolites) or biogas. Photosynthetic oxygen production also reduces the need for external aeration, which is especially advantageous for the treatment of hazardous pollutants that must be
Continuous supermacroporous chromatographic columns with anion-exchange ligands [2-(dimethylanlino)ethyl group] and immobilized metal affinity (IMA) ligands (Cu2+-loaded iminodiacetic acid) have been developed allowing binding of Escherichia coli cells and the elution of bound cells with high recoveries. These poly(acrylamide)-based continuous supermacroporous columns have been produced by radical
This master thesis is written at the request of Kockums AB to solve the need for flexible fire barriers on submarines, particularly for the future submarine class A26. The report uses event tree analysis to demonstrate that a lower fire resistance classification for decks and bulkheads, compared to the prescriptive rules, is sufficient to obtain a satisfactory level of safety. The thesis also incl
Electrical asymmetrical flow field-flow fractionation (EAF4) is an interesting new analytical technique that separates proteins based on size or molecular weight and simultaneously determines the electrical characteristics of each population. However, until now, the research using EAF4 has not been published except for the proof-of-concept in the original publication by Johann et. al. in 2015 [1].
Circumplanetary discs (CPDs) form around young gas giants and are thought to be the sites of moon formation as well as an intermediate reservoir of gas that feeds the growth of the gas giant. How the physical properties of such CPDs are affected by the planetary mass and the overall opacity is relatively poorly understood. In order to clarify this, we use the global radiation hydrodynamics code FA
Between 2024 and 2026, AI providers launched dedicated agent products and presented them as tools that can plan, decide and carry out marketing tasks with greater independence than earlier generative AI. On LinkedIn, Swedish marketing executives and industry opinion leaders produce a parallel discourse that reaches the same professional audience. This study examines how the relationship between th
Background The clinical distinction between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is sometimes difficult, particularly in mild cases. Although CSF markers such as amyloid beta 42 (A beta 42) and P-tau can distinguish between AD and normal controls, their ability to distinguish between AD and DLB is not adequate. Objective This study aims to investigate whether CSF markers, i
This thesis evaluates the performance of an EPR programme for post-consumer PET waste management by PET recycling company (PETCO) in South Africa. It analyses waste management policies of South Africa that are relevant to EPR. Using a set of evaluative tools, the thesis reveals areas for improvement in the EPR scheme. It also identifies areas in informal sector interventions where EPR can contribu
The directive to close the dumpsite in Kisumu, Kenya has made the search for alternative solid waste treatment and disposal technologies urgent. The aim of this research is to support the decision-making process by analyzing multiple socioeconomic and environmental parameters of salient solid waste treatment options. We used multi-criteria analysis to assess and compare anaerobic digestion, sanita
Conspecific tolerance is key for maintaining group cohesion in animals. Understanding shifts from conspecific tolerance to intolerance is therefore important for understanding transitions to sociality. Subsocial species disperse to a solitary lifestyle after a gregarious juvenile phase and display conspecific intolerance as adults as a mechanism to maintain a solitary living. The development of in
Solar energy is an important source of clean energy to combat climate change issues that motivate the establishment of solar farms. Establishing solar farms has been considered a proper alternative for energy production in countries like Mozambique, which need reliable and clean sources of energy for sustainable development. However, selecting proper sites for creating solar farms is a function of
Seaweeds (macroalgae) are an attractive resource for diverse microbial- and enzymatic production processes. They are abundant, underutilized, cheap, and rich in carbohydrates, and therefore have the potential to be used as a source of mono- or oligosaccharides, and as substrates for industrial fermentation processes. Many seaweed polysaccharides, including the sulfated polysaccharides ulvan and fu
Multiple myeloma is a heterogeneous hematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2.
GUNILLA JARLBRO professor, Lunds universitet MARGARETA WINBERG ambassadör och f.d. statsråd (S) HANNA BÄCK professor, Lunds universitet GUDRUN SCHYMAN Feministiskt initiativ HANNA BLOMBERG violin KRISTIAN WOLSKI cittern ELIN GUSTAFSSON kommunalråd (S), Lund MIA MARIE HAMMARLIN docent, Lunds universitet BARBRO WESTERHOLM Liberalerna LENITA FREIDENVALL docent, Stockholms universitet TACK TILL Samhäl
https://www.lu.se/sites/www.lu.se/files/seminarium_folder_8_mars_digital_002_2018.pdf - 2026-07-03
Readership Course Sida 1 av 3 Centre for Engineering Education LTH SYLLABUS GB_S91 Datum 2012-10-08 Revised 2023-01-01 Readership Course (Docentkurs) The Readership Course is a course in preparation for appointment as a reader/docent at LTH, as well as a qualifying course in teaching and learning in higher education at LTH. The course addresses topics of relevance for a future reader/docent at LTH
https://www.cee.lth.se/en/sites/cee.lth.se.en/files/2026-05/Syllabus_readership%20course_GB_S91_2023-01-01.pdf - 2026-07-03
