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Policy brief mhm saragabrielsson

Towards Sustainable Menstrual Health Management in Tanzania POLICY BRIEF FROM LUND UNIVERSITY CENTRE FOR SUSTAINABILITY STUDIES | 2018 POLICY BRIEF For any girl or woman in the world periods can be a struggle. In Tanzania, lack of hygiene products and potable water, sanitation facilities and waste collec- tion systems, along with deeply rooted taboos makes the menstrual cycle even harder. Poor Men

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/policy_brief_mhm_saragabrielsson.pdf - 2026-05-26

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Induction of platelet thrombi by bacteria and antibodies.

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Similarity-Based Grouping of a Universe of Securities

Securities can be classified in multiple ways. One of the most common ways to classify securities is using Morningstar’s label system. For instance a fund can be Large-Value or Small-Growth. However, these systems have inherit limitations that makes it hard to properly maximize diversification in the selection of a portfolio. In this thesis, we present a method to classify securities that allows f

Impact of comorbidity on disease characteristics, treatment intent and outcome in diffuse large B-cell lymphoma : a Swedish lymphoma register study

Background: Comorbidity impacts overall survival amongst patients with diffuse large B-cell lymphoma (DLBCL). However, associations of comorbidity with lymphoma characteristics, treatment selection and lymphoma-specific mortality are less well known. Objective: To examine the impact of comorbidity on DLBCL characteristics, treatment intent and cause of death. Methods: We identified 3905 adult pati

Clinical studies of extended-half-life recombinant FVIII products for prophylaxis in adults and children : A critical review from the physician's perspective

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller

Varsel-till-berord-facklig-organisation

DATUM Dnr Skickas till berörd arbetstagarorganisation: Saco-S □ OFR/S □ SEKO □ Varsel enligt 30 a § första stycket lagen (1982:80) om anställningsskydd om besked enligt 15 § samma lag. Lunds universitet har lämnat Er medlem, ………………………………………..(namn, pnr) besked enligt 15 § lagen om anställningsskydd om att han/hon inte kommer att få fortsatt anställning, när den nuvarande tidsbegränsade anställning

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2025-12/varsel-till-berord-facklig-organisation.pdf - 2026-05-26

A Spatial Relations Study of Virus Infected Cells and the Human Immune Response through the V-Proportionality Measurement

Biotechnological tools have never been stronger than today and the data they provide is absolutely fascinating. As we get a clearer picture of the intricate workings of living systems eective mathematical and statistical tools become a necessity in order to reach a comprehensive understanding of said systems. The purpose of this thesis is to statistically explore cutting edge biomedical data taken

Computational science: Theoretical Biophysics (BERN08), 7.5 credits

This course deals with applications of physics in biology. You will learn about various physical processes of biological importance, such as random walks and osmotic pressure, and how these can be described theoretically with concepts and tools mainly from statistical mechanics. The course begins with a brief primer on cell and molecular biology, aimed at physicists and others who have not previou

https://www.cec.lu.se/education/undergraduate-advanced-studies/computational-science-studies/theoretical-biophysics - 2026-05-25