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Physiochemical degradation of therapeutic proteins in vivo during plasma circulation after administration can have a detrimental effect on their efficacy and safety profile. During drug product development, in vivo animal studies are necessary to explore in vivo protein behaviour. However, these studies are very demanding and expensive, and the industry is working to decrease the number of in vivo

In the area of adapting/constructing homes and workplaces for the physically disabled, a computer-based planning tool has been prototyped and evaluated. The prototypes so far have been based on Macintosh computers and commercially available 3-D modeling and multimedia programs. Six case-studies formed the basis for user-oriented prototyping and evaluation. The present prototype was found useful in

Kerma-area product (KAP) meters have a pronounced energy dependence when measuring air KAP for lightly filtered X-ray beams (RQR). Today, it is also common with more heavily filtered beams. In this work, the energy dependence for lightly as well as heavily filtered beams (RQC) was investigated for several KAP meter models. The relative energy dependence of the readings of an external and an intern

Microsoft Word - course outlineWaS_20 Water and sustainability (7.5 hc) Water is one of the most important substances on earth. The UN has defined 17 sustainable development goals in its 2030 Agenda for Sustainable Development. For almost every goal, a sustainable use of water and water resources are needed for achieving the goal. But what is sustainability? What are the most important challenges?

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/2021-03/Course%20outline_Water%20and%20sustainability_2021.pdf - 2026-05-26

ARTICLE Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study Maria Lönnrot1,2 & Kristian F. Lynch3 & Helena Elding Larsson4,5 & Åke Lernmark5,6 & Marian J. Rewers7 & Carina Törn4,5 & Brant R. Burkhardt3 & Thomas Briese8,9 & William A. Hagopian10 & Jin-Xiong She11 & Olli G. Simell12,13 & Jorma Toppari14,15 & Anette-G. Ziegler16,17 & Beena

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/74%2010262018_679_74_MP22a_Lonnrot_Diabetologia_2017.pdf - 2026-05-26

Complete blood counts with red blood cell determinants associate with reduced beta‐cell function in seroconverted Swedish TEDDY children Endocrinol Diab Metab. 2021;4:e00251.  | 1 of 10 https://doi.org/10.1002/edm2.251 wileyonlinelibrary.com/journal/edm2 Received: 24 November 2020  | Revised: 1 March 2021  | Accepted: 22 March 2021 DOI: 10.1002/edm2.251 O R I G I N A L R E S E A R C H A R T I C L

https://www.teddy.lu.se/sites/teddy.lu.se/files/2022-10/133_MP239_Salami_EndoDiabMetab_2021.pdf - 2026-05-26

The building sector is the largest contributor to greenhouse gas (GHG) emissions, primarily due to two factors: the embodied energy of construction materials and the operational energy consumed over a building’s lifespan. Given this substantial environmental impact, sustainability and climate resilience have become critical priorities in global policy frameworks. Addressing this challenge requires

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Unpaid Care for Elderly Parents and Labor Supply Among Older Working-Age Men and Women Across Europe ELISA LABBAS, MARIA STANFORS LUND PAPERS IN ECONOMIC DEMOGRAPHY 2022:4 Unpaid care for elderly parents and labor supply a

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/LPED%202022%204.pdf - 2026-05-26

Master’s programme in International Marketing and Brand Management – Statement of purpose, year 2024/2025 1/42023-10-16 Master’s programme in International Marketing and Brand Management STATEMENT OF PURPOSE | YEAR 2024/2025 The statement of purpose is one of the most important, and challenging, elements of your application. It is your opportunity to stand out from the hundreds of other ap- plican

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-02/Statement%20of%20purpose%202024-25%20IMBM.pdf - 2026-05-26

GLP-1 receptor agonists may provide an alternative to prandial insulin for advancing basal insulin therapy. Harmony 6 was a randomized, open-label, active-controlled trial testing once-weekly albiglutide vs thrice-daily prandial insulin lispro as an add-on to titrated once-daily insulin glargine.RESEARCH DESIGN AND METHODS: Patients taking basal insulin (with or without oral agents) with HbA1c 7-1

We performed a systematic, large-scale analysis of human protein complexes comprising gene products implicated in many different categories of human disease to create a phenome-interactome network. This was done by integrating quality-controlled interactions of human proteins with a validated, computationally derived phenotype similarity score, permitting identification of previously unknown compl

Popular Abstract in Swedish Två observationer tjänar som utgångspunkt för denna avhandling: (1) globaliseringens allt snabbare och mer eller mindre gränslösa flöde av information har medfört ökad press på företag och organisationer, liksom stater och regioner, att ständigt förnya sig för att kunna behålla sin konkurrenskraft. (2) kunskapsintensiv industri tenderar att samlas i geografisk närhet tiThe accelerated speed and intensity of global interconnections in all segments of society during the last couple of decades have had a profound impact on the workings of contemporary capitalism. Increased pressure is put on national and regional economies to continuously upgrade their competitive advantages, at the same time as new learning opportunities occur at a faster rate than ever. For reaso

The production of ethanol based on lignocellulosic biomass requires the fermentation of a hydrolysate containing hexose and pentose sugars in an inhibitory environment. In fact, the lignocellulosic hydrolysate obtained from pretreatment and hydrolysis of the raw material contains a variety of inhibitory compounds, including (i) the furaldehydes 5-hydroxymethyl-2-furaldehyde (HMF) and 2-furaldehyde

Abstract in UndeterminedThis article considers a distribution inventory system consisting of N retailers and a regional support warehouse, all being replenished from a central warehouse/outside supplier. For the case where stock-outs occur, the retailers receive transshipments from the support warehouse at an extra cost. A model is presented for cost evaluation and optimization of the reorder poin

The number of people who choose e-books rather than reading traditional paper books are increasing as a result of our world becoming more digitized. Libraries need to keep up with this trend and modernize its lending procedures for their digital products. The purpose and goal of this Master thesis were to answer the questions how e-books can become more attractive to those who have not yet dared t

Globalization has brought numerous benefits to the world economy in general. On the one hand, it has contributed by giving opportunities and improving the quality of life of many people. It has also boosted some local markets in developing countries by giving local people employment as well as increasing their GDP, due to the fact that a vast amount of natural resources are found there. From the “

Naturens resurser är inte oändliga och förnyas inte i samma hastighet som vi förbrukar dem. Genom att återvinna, minskar inte bara avfallsmängden som deponeras, utan råmaterial behöver inte förbrukas i samma utsträckning. I Sverige har vi idag en väl utbyggd återvinning där ansvaret för omhändertagande och insamling av avfall från hushåll ligger hos kommunerna, med undantag för de produkter som omEmeli Magnusson (2015) MVEK03 Natural resources are not infinite and are not renewed in the same rate as we consume them. Recycling outweighs a part of the consumption of resources, and the environmental impacts, resulting from the manufacture of new products. Recycling is an important part of getting a sustainable society, it brings us an opportunity to recycle material resources. This study exa

Prostate cancer is one of the most commonly diagnosed diseases among men, both in Sweden and the US. It is a consuming disease that tears on both the patient and his relatives. The different stages of disease are many, as are the different treatment options and drugs. New diagnostic techniques are constantly being developed and more imaging methods become available. As new digital techniques evolv

Automation with the use of robotics is a crucial trend across industries, enhancing efficiency and quality while improving health and safety conditions by minimizing human exposure to hazardous tasks. Alfa Laval, a global provider of products within heat transfer, separation, and fluid handling, is embracing this trend by exploring how to solve labor-intensive processes like the production of rubb