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Top-down estimates of European CH4 and N2O emissions based on four different inverse models

European CH4 and N2O emissions are estimated for 2006 and 2007 using four independent inverse modelling systems, based on different global and regional Eulerian and Lagrangian transport models. This ensemble approach is designed to provide more realistic estimates of the overall uncertainties in the derived emissions, which is particularly important for verifying bottom-up emission inventories. We

Outcome of poor response paediatric AML using early SCT

Background Children with poor response acute myeloid leukaemia (AML) generally have a very poor outcome. Allogeneic stem cell transplantation (SCT) is often recommended for these children but the benefit is unclear. The aim of this study was to investigate survival for poor response AML patients treated with SCT. Material and Methods Treatment was given according to the NOPHO-AML 2004 protocol. Al

Corticotropin-induced reduction of plasma lipoprotein(a) concentrations in healthy individuals and hemodialysis patients: relation to apolipoprotein(a) size polymorphism

Lipoprotein(a) [Lp(a)], a strong independent cardiovascular risk factor, consists of the unique apolipoprotein(a) [apo(a)] covalently linked to a low-density lipoprotein particle. Apo(a) contains a widely differing number of the plasminogen-like kringle IV, a size polymorphism that is codominantly inherited. In addition to powerful genetic control, renal failure is known to influence the plasma Lp

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INTRODUCTION: Information about the education, training and future employment prospects of Icelandic surgeons has not been available.MATERIALS AND METHODS: The study included all Icelandic surgeons, in all subspecialties, educated at the Faculty of Medicine at the University of Iceland. Information on specialty training, higher academic degrees and in which country these were obtained was collecte

Dinosaur : A Refined Open-Source Peptide MS Feature Detector

In bottom-up mass spectrometry (MS)-based proteomics, peptide isotopic and chromatographic traces (features) are frequently used for label-free quantification in data-dependent acquisition MS but can also be used for the improved identification of chimeric spectra or sample complexity characterization. Feature detection is difficult because of the high complexity of MS proteomics data from biologi

Complementary strategies to improve positive response and outcome in patients with advanced heart failure undergoing CRT therapy

AbstractCardiac resynchronization therapy (CRT) has improved quality of life and survival in select heart faillure patients, however 30-40% of patients do not show objective benefit from the treatment. At the same time there is little evidence about the long term effect of changes in medical treatment in these patients. Several factors have been examined to improve the response rate in the ”non-re

En närstående rättighet för presspublikationer på den digitala inre marknaden - En studie av artikel 15 i direktiv (EU) 2019/790 om upphovsrätt och närstående rättigheter på den digitala inre marknaden

I dagens digitaliserade samhälle möter utgivare och publicister av traditionellt tryckt media stora ekonomiska motgångar vid försäljningen av exempelvis nyhetstidningar eller andra tidskrifter. Således har majoriteten av utläggare idag gjort sina publikationer tillgängliga för läsare online. De digitala intäkterna lyckas dock inte väga upp för de förluster utgivarna lider av den nedåtgående försälIn today's digitized society, publishers of legacy printed media face major financial hardships in the sale of newspapers and other magazines. Thus, most publishers today have made their publications available to readers online. However, digital revenues do not make up for the losses that the publishers suffer from the decreasing sales of printed media. This can in part be attributed to the fa

Review of Asylum Policies and Procedures in The Bahamas: Are Current Policies and Procedures Consistent with International Instruments for the Protection of Refugees?

Volatile conflicts, poverty and suppression of basic human rights stemming from one's political or religious affiliations, gender and race, are some of the various reasons why thousands flee home in the hopes of finding some kind of security. As the world observes the appalling deterioration of conflicts in Western Sudan, Iraq and Haiti, we simultaneously observe neighbouring or developed coun

Molecular Epidemiology of Breast Cancer

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen i världen bland kvinnor och bara i Sverige insjuknar varje år runt 7000 personer. Vi vet att omkring 10-15% av fallen troligen beror på ärftliga faktorer och det har under senare tid gjorts stora insatser för att klargöra exakt vilka arvsanlag som har betydelse för utveckling av sjukdomen. Under början av 90-talet identifieradeHereditary breast cancer constitutes a considerable fraction of the total number of breast cancer cases occurring each year. Up until recently very few breast cancer predisposing genes were known, but many new common polymorphisms contributing to increased cancer susceptibility are continuously being identified. This thesis has focused on familial breast cancer and identifying as well as investi

No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression

A polymorphism consisting of a deletion near the 5' splice site of exon 18 on the alpha2-macroglobulin (A2M) gene (A2M-2) has been suggested to be associated with Alzheimer's disease (AD) in family-based studies. We studied the A2M-2 allele together with the ApoE alleles in a large series on patients with AD (n = 449) and age-matched controls (n = 349). Neuropathologically confirmed diagnoses were

Comparison of clinical and neuroradiological findings in first-ever stroke. A population-based study

BACKGROUND AND PURPOSE: To determine how a recently proposed clinical stroke subclassification corresponds to specific findings on computed tomography (CT) and magnetic resonance imaging (MRI) of the brain. METHODS: Two hundred twenty-eight patients with first-ever stroke were divided into four clinical subgroups: (1) total anterior circulation syndrome: both cortical and subcortical symptoms from

Clothing Insulation Required for Energy Efficiency (IREQee) and Thermal Comfort

Thermal comfort has direction implications for energy efficiency and sustainable development. From a global perspective, about 40% of total primary energy is used in buildings, contributing to more than 30% of CO2 emissions [1]. The fact that the common practices of clothing choices have impact on energy efficiency is ignored [2-3]. This paper analyzed and proposed clothing insulation required for

Three-dimensional structures and functional studies of two GH43 arabinofuranosidases from Weissella sp. strain 142 and Lactobacillus brevis

Arabinofuranosidases degrade arabinose-containing oligo and polysaccharides, releasing l-arabinose, which is a potentially useful sugar, shown to reduce glycemic response under certain conditions. Arabinofuranosidases (Arafs) are frequently found in GH43, one of the most common GH-families encoded in genomes in gut microbiota, and hence it is of interest to increase understanding of the function o

Complicated COVID-19 in pregnancy : a case report with severe liver and coagulation dysfunction promptly improved by delivery

BACKGROUND: It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exagg

Prevalence of crowding, boarding and staffing levels in Swedish emergency departments - A National Cross Sectional Study

Background: Emergency Department (ED) crowding occurs when demand for care exceeds the available resources. Crowding has been associated with decreased quality of care and increased mortality, but the prevalence on a national level is unknown in most countries. Method: We performed a national, cross-sectional study on staffing levels, staff workload, occupancy rate and patients waiting for an in-h

Prediction of Postoperative Delirium After Cardiac Surgery with A Quick Test of Cognitive Speed, Mini-Mental State Examination and Hospital Anxiety and Depression Scale

Purpose: To evaluate if preoperative assessment with A Quick Test of Cognitive Speed (AQT) could increase the accuracy of predicting delirium after cardiac surgery compared to Mini-Mental State Examination (MMSE), and examine if a composite of variables, including cognitive function and depressive symptoms, could be useful to predict delirium. Patients and Methods: Cardiac surgery was performed in

Incidence and outcomes of acute mesenteric ischaemia : a systematic review and meta-analysis

Objective To estimate the incidence of acute mesenteric ischaemia (AMI), proportions of its different forms and short-term and long-term mortality. Design Systematic review and meta-analysis. Data sources MEDLINE (Ovid), Web of Science, Scopus and Cochrane Library were searched until 26 July 2022. Eligibility criteria Studies reporting data on the incidence and outcomes of AMI in adult populations

Supply chain visibility : A Delphi study on managerial perspectives and priorities

Visibility across supply chains has been a key concern for organisations for many years, but the tools and information systems to achieve real-time visibility have not been available until recently. In response to uncertainty and complexity, advanced information and communication technologies have been explored for supply chain visibility (SCV). However, managerial perspectives are largely absent

Measuring the Capabilities of the Swedish Fire Service to Save Lives in Residential Fires

The ability of the fire service to save lives in building fires has a profound impact on planning. However, very little empirical data are available on how different factors affect this capability—or even how many that are rescued annually. The current paper aims to partly fill this gap with an assessment of all rescues performed by the fire departments in Sweden during 2017. A combination of inci

Fewer Community-Acquired Colds with Daily Consumption of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2. A Randomized, Placebo-Controlled Clinical Trial

BACKGROUND: Viral infections of the upper airways are the most common cause for absence from work or school, and there is evidence for probiotic efficacy in reducing the incidence and severity of these infections.OBJECTIVES: We aimed to confirm the previously reported beneficial effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 against community-acquired common