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Background Toluene-2,5-diamine (PTD) is the most frequently used dye in oxidative hair dyes on the Scandinavian market. However, little is known about immune responses to PTD-containing oxidative hair dyes. Objectives To study immune responses induced by PTD-containing hair dyes in mice. Methods Immune responses against two different permanent hair dye products containing 1·60% (w/w) and 0·48%

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The expected increase in both consumption and production of electricity strains the Swedish electricity grid, necessitating both reinforcement and expansion. Concurrently, the need to decarbonise heavy industry is becoming more urgent to achieve the EU Climate neutrality goal by 2050, with hydrogen anticipated as a key player. Hybrid energy systems that combine the generation of renewable electric

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The evolution into a networked society, where a wide variety of devices are connected to the Internet, opens up many new opportunities for creating smart products and applications that dynamically adapt to the current environment. A common scenario will be that applications require or benefit from using several devices at the same time for the execution. Such distributed applications may be comple

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Environmental certification for buildings has become more common since the first certification system became available on the market in the 90s. Today there are hundreds of thousands buildings with an environmental certification. More and more companies choose to place their business in a certified building. The problem when companies are in the election of a new facility may be the lack of knowle

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Purpose: To estimate inter-observer agreement with regard to describing adnexal masses using the International Ovarian Tumor Analysis (IOTA) terminology and the risk of malignancy calculated using IOTA logistic regression models LR1 and LR2, and to elucidate what explained the largest inter-observer differences in calculated risk of malignancy. Experimental Design: 117 women with adnexal masses we

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Sensitive detection of short nucleic acids is used to identify viral and bacterial diseases, detect biomarkers of cancer, as well as in gene expression studies. Currently available techniques such as PCR, electrochemical detection and SPR are typically costly and often require amplification of the DNA. Here, we demonstrate a sensing system for picomolar detection of short single-stranded DNA by fl

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Reconstructions and simulations disagree on whether the Holocene exhibited a long-term cooling or warming signal. Anthropogenic land-use could be an important forcing regionally, but available population-based estimates differ widely. We examine transient Holocene climate model simulations forced with three population-based disturbed-land reconstructions and compare this with a fourth scenario der

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Most patients with symptoms suggestive of chronic coronary syndrome (CCS) have no obstructive coronary artery disease (CAD) and better selection of patients to be referred for diagnostic tests is needed. The CAD-score is a non-invasive acoustic measure that, when added to pretest probability of CAD, has shown good rule-out capabilities. We aimed to test whether implementation of CAD-score in clini

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Isolation of DNA from blood and buccal swabs in adequate quantities is an integral part of forensic research and analysis. The present study was performed to determine the quality and the quantity of DNA extracted from four commonly available samples and to estimate the time duration of the ensuing PCR amplification. Here, we demonstrate that hair and urine samples can also become an alternate sou

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Purpose of Review: Osteoarthritis (OA) is the most common forms of arthritis in the general population, accounting for more pain and functional disability than any other musculoskeletal disease. There are currently no approved disease modifying drugs for OA. In the absence of effective pharmacotherapy, many patients with OA turn to nutritional supplements and nutraceuticals, including collagen der

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Inom läkemedelssektorn, originalföretagen som investerar stora summor pengar i forskning och utveckling av nya läkemedel vanligtvis söker patent för flera skyddsområden. De försöker utnyttja det monopol ett patent ger för att skydda sina egna originalläkemedel mot generiska läkemedels marknadsinträde och utebliven vinst som det för med sig. Generiska företag för att kunna lansera sina generiska prIn the pharmaceutical sector, originator companies that invest large sum of money in R&D of new medicines usually file patent applications for several areas of protection. They try to take advantage of a monopoly that a patent grants to protect their medicines against generic entry on the market and consequently the loss of profits. Generic companies in order to be able to launch their generic

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Sentinel lymph node dissection is widely used in the staging of endometrial cancer. Variation in surgical techniques potentially impacts diagnostic accuracy and oncologic outcomes, and poses barriers to the comparison of outcomes across institutions or clinical trial sites. Standardization of surgical technique and surgical quality assessment tools are critical to the conduct of clinical trials. B

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The Jk(a-b-) phenotype results from alterations in the JK gene and is characterized by absence of the RBC urea transporter in the cell membrane. The frequency of Jk(a-b-) varies among populations, but this phenotype is most commonly found in people of Polynesian and Finnish descent. Although rare, Jk(a-b-) individuals present a clinical challenge because anti-Jk3 is produced readily in response to

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The oxidation of ammonia is a key reaction for the production of artificial fertilizers and for environmental protection. Depending on the area of application, the catalytic reaction needs to be tuned toward the production of either N2 or NO, and this selectivity is controlled by temperature, pressure, reactant ratio, and the type of catalyst. PtRh alloys are highly useful catalytic materials for

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Recently, the consumer interest and revenue from domestic aide robots have been rapidly increasing. A report from 2018 estimates that the global revenue from this sector will rise from $6.4 billion to nearly $23 billion by 2022, an increase by 250%. This thesis covers a concept development process defining a multi-purpose, autonomous household robot. The focus user group is consumers, and it is ai

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Huge amounts of greenhouse gases continuously released into the atmosphere is of large global concern. Carbon dioxide makes up a large part of released greenhouse gases. Especially the aircraft industry, which is experiencing a steady annual increase as air travel grows in popularity. This business sees 72% of all its combustion products in aircraft exhausts to be carbon dioxide. Swedavia, a compa

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Cell death is an important field of biology that is linked to many other topics in medicine and biology. One of the methods to investigate cell death is through high content screening (HCS) which makes use of robotic microscopy. By this technology, cell death associated organelle membrane permeabilisation and the localisation of certain dyes can be visualised and elucidate a substantial amount of

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En av polisens metoder för att bedriva spaning är genom provokatörer. Provokatörer kan genomföra provokativa åtgärder. Om ett brott begås efter att en provokativ åtgärd vidtagits får den tilltalade inte dömas om dennes rätt, enligt europakonventionen, blivit oåterkalleligen undergrävd. Enskilds rätt är att anse som oåterkalleligen undergrävd om denne provocerats till att begå en typ av gärning som

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The cinnamyl phenylpropyl fragrance ingredients are a diverse group of chemical structures that have similar metabolic and toxicity profiles. A toxicological and dermatological review of these fragrance ingredients is presented. The common characteristic structural element of cinnamyl phenylpropyl materials is an aryl substituted primary alcohol/aldehyde/ester. For high end users, calculated maxim