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BACKGROUND: Complete atrioventricular block (CAVB) is a major reason for implantation of permanent pacemakers, but knowledge of CAVB inheritance is sparse. This nationwide study aimed to determine the occurrence of CAVB in first-, second-, and third-degree relatives (full siblings, half-siblings, and cousins).METHODS: The Swedish multigeneration register was linked to the Swedish nationwide patien
X-ray crystallography is the main source of atomistic information on the structure of proteins. Normal crystal structures are obtained as a compromise between the X-ray scattering data and a set of empirical restraints that ensure chemically reasonable bond lengths and angles. However, such restraints are not always available or accurate for nonstandard parts of the structure, for example substrat
In 1997 Sweden was the third biggest exporter of popular music in the world. This astonishing fact has often been explained as being the result of the large investments in municipal music schools that took place in Sweden from 1940. The explanation holds an interesting paradox. Most municipal music schools began with the aim to teach young people appreciate more valuable music (i.e. classical) tha
This paper reports on studies of multiple-injection strategies of gaseous fuel in a model combustion chamber and the role of jet-jet interactions on the mixing processes in the chamber using large-eddy simulation (LES). A high-pressure non-reacting gas flow injected through a jet with a nozzle diameter of 1.35 mm into a quiescent inert air environment is considered. First, we validate the method a
Cigarette smoking is a key factor for the development and progression of different cancers including mammary tumor in women. Resveratrol (Res) is a promising natural chemotherapeutic agent that regulates many cellular targets including p21, a cip/kip family of cyclin kinase inhibitors involved in DNA damage-induced cell cycle arrest and blocking of DNA replication and repair. We have recently show
Objectives: We aimed to describe the cardiopulmonary function during exercise and the health-related quality of life (HRQoL) in patients with a history of COVID-19 pneumonia, stratified by chest computed tomography (CT) findings at baseline. Methods: Among 77 consecutive patients with COVID-19 who were discharged from the Pulmonology Ward between March 2020 and April 2021, 28 (mean age 54.3 ± 8.6
Objectives: Smoking cessation programmes in which groups of smokers have the opportunity to learn behavioural techniques and benefit from mutual support for quitting are widely available. The aim of this review is to determine the effectiveness of smoking cessation programmes delivered in a group format, for helping smokers achieve long-term smoking cessation. Search strategy: TheTobacco Addicitio
När forskare blickar ut i universum ser de överallt spåren av en stor mängd osynlig massa. Massan finns där men det går inte att se den. Ungefär 80% av all massa i universum beräknas bestå av denna "mörka materia". Det är som att mänskligheten står på stranden och blickar ut över havet utan att veta vad vatten är. I partikelfysik studeras universums minsta beståndsdelar, elementarpartiklarna, för The high event rate delivered by the Large Hadron Collider (LHC) provides experiments with opportunities for new discoveries as well as challenges related to the large amounts of data recorded. Overcoming this requires innovative techniques in the three topics of this thesis: Data acquisition, data analysis, and data compression.In the data taking period of 2015-2018, the ATLAS experiment received
Background: Familial prostate cancer risk estimates are inflated by clinically insignificant low-risk cancer, diagnosed after prostate-specific antigen testing. We provide age-specific probabilities of non-low- and high-risk prostate cancer. Methods: Fifty-one thousand, eight hundred ninety-seven brothers of 32 807 men with prostate cancer were identified in Prostate Cancer data Base Sweden (PCBaS
Importance: The role of ω-3 polyunsaturated fatty acids for primary prevention of coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than biomarkers. Objective: To evaluate biomarkers of seafood-derived eicosapentaenoic acid (EPA; 20:5 ω-3), docosapentaenoic acid (DPA; 22:5 ω-3), and docosahexaenoic acid (DHA; 22:6 ω-3) an
Background: A juxtarenal abdominal aortic aneurysm is defined as a short (less than 4mm) or no-neck aneurysm, which is often treated with open or complex endovascular repair. The evidence to support the best treatment strategy is scarce. The aim of this study was to assess the short- and mid-term outcomes of elective open surgical repair or fenestrated endovascular aneurysm repair for juxtarenal a
International law related to patents, on the one side, and human rights, on the other, both constitute interesting areas of law on their own. From time-to time the two distinct fields of international law intertwine. A tragic but highly relevant example is the ongoing HIV/AIDS epidemic. The core of law-related considerations of the HIV/AIDS epidemic consists of specific parts of the two fields, na
Volatile conflicts, poverty and suppression of basic human rights stemming from one's political or religious affiliations, gender and race, are some of the various reasons why thousands flee home in the hopes of finding some kind of security. As the world observes the appalling deterioration of conflicts in Western Sudan, Iraq and Haiti, we simultaneously observe neighbouring or developed coun
I ett aktiebolag eller motsvarande bolagsform med begränsat ansvar för aktieägarna står aktiekapitalet i centrum. Lagstadgat krav på aktiekapital har förekommit i somliga rättsordningar. I vissa länder har kapitalkravet eftergetts. I detta arbete kommer att göras en komparativ jämförelse mellan Tysklands, Storbritanniens, Sveriges och EU:s aktiebolagsformer med avseende på minsta kapitalkravet i bIn a limited liability company or similar corporate form with limited liability for the shareholders the legal capital plays an important role. The minimum capital requirements have appeared in some jurisdictions. In some countries, the minimum capital requirement have been abolished. This work will be a comparative comparison between German, British and Swedish companies rules with focus on the m
Recent global warming trends, particularly in the arctic regions and Himalayas are modifying forest structure and function, notably biogeographical changes in tree species distribution together with alteration in Net Primary Production (NPP), Leaf Area Index (LAI) and Carbon biomass. These alterations are most pronounced in mountain environments, carrying significant impacts on woody species which
The Pacific marten (Martes caurina) is thought to be a forest specialist closely linked to older forests with high canopy cover and dense shrubs. It is therefore highly surprising that a small population have been found in the coastal sand dunes in Oregon, United States. The martens seem to be choosing this habitat even though large areas of older forests are available just next to the dunes. With
En fastighetsaffär är för de allra flesta en stor affär, kanske den allra största man gör i sitt liv, och konsekvenserna kan därför också bli stora, både för köpare och säljare. En av frågeställningarna vid ett köp är ansvarsfördelningen mellan köpare och säljare och det finns många rättsfall genom åren där köparens undersökningsplikt vid köp av fast egendom prövas i svenska domstolar. Enligt JordA property transaction is for most people an important deal, and the impact can therefore also be great, both for buyers and sellers. One of the issues of a purchase is the division of responsibilities for errors between the buyer and the seller, and there are many court cases over the years where the buyer's duty to investigate the purchase of property is tried in Swedish courts. According to
There is significant evidence to suggest that diets that include high levels of meat consumption have negative effects on both the environment and human health. As a result, efforts are being made to identify and characterize more plant-based proteins, such as those found in rapeseed. Rapeseed is the second-largest oilseed crop worldwide and is primarily used to produce edible oils through mechani
Background The two main functional goals of postural control are postural stability (balance) and postural orientation. Postural orientation is the ability to maintain alignment between body segments and the environment during a static or dynamic activity. Nae et al. have evaluated the measurement properties of a clinical test battery for assessing postural orientation errors (POEs) in patients wi
Objectives: – To quantify the risk of incident psychiatric morbidity after community-acquired sepsis and assess whether new chronic diseases mediate the association. Design: – Nationwide, population-based matched register cohort; hazards estimated with weighted Cox regression. Setting: – Sweden, linking the National Quality Sepsis Registry, National Patient Register, Prescribed Drug Register, and
