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Identification of biomarkers associated with protection from developing diabetic complications is a prerequisite for an effective prevention and treatment. The aim of the present study was to identify clinical and plasma metabolite markers associated with freedom from vascular complications in people with very long duration of type 1 diabetes (T1D). Individuals with T1D, who despite having longer
Background: Several biologically plausible mechanisms have been proposed to mediate the association between periodontitis and atherosclerotic vascular disease (AVD), including adverse effects on vascular endothelial function. Circulating endothelial progenitor cells (cEPCs) are known to contribute to vascular repair, but limited data are available regarding the relationship between cEPC levels and
Purpose: To validate a new 2D-3D registration method of fusion imaging during aortic repair in a system prepared only for 3D-3D registration and to compare radiation doses and accuracy. Materials and Methods: The study involved 189 patients, including 94 patients (median age 70 years; 85 men) who underwent abdominal endovascular aneurysm repair (EVAR) with 2D-3D fusion on an Artis zee imaging syst
As the need of environmentally friendly alternatives to fossil fuels is growing bigger, so is the need for knowledge and research around possible new raw materials that could serve that pur-pose. One discussed product is biogas. Since biogas can be produced from not only food waste and wastewater residue, but from any substrate that contains fats, proteins and/or car-bohydrates, with the help of d
This research characterized the barrier properties and transport mechanisms of multilayer films comprising polylactide (PLA), chitosan, and nanocelluloses extracted from agricultural by-products. The investigation employed complementary analytical techniques to evaluate water vapor and oxygen transport behavior, comparing cellulose nanofibers (CNF) and cellulose nanocrystals (CNC) derived from cor
OBJECTIVES: Diabetes mellitus (DM) has a strong genetic component and is a known risk factor for several hand conditions. We aimed to examine whether DM in first-degree relatives is associated with an increased risk of hand surgical diagnoses.DESIGN: A retrospective cohort study.SETTING: Data were collected from a population-based cohort in southern Sweden (Malmö Diet and Cancer Study (MDCS)). Fam
Syftet med uppsatsen är att studera vad domstolarna får döma över och vilka värden den svenska straffrätten bygger på. För att undersöka vad domstolarna får döma över har jag behandlat de krav på gärningsbeskrivningens omfattning som ställs i RB 30:3. Därtill undersöks vad lagen och förarbeten behandlar om materiell processledning. För att kunna undersöka straffrättens värden använder jag mig av
BACKGROUND AND OBJECTIVE: Achieving adequate concentrations of beta-lactam antibiotics in patients with severe infections is challenging, and therefore therapeutic drug monitoring (TDM) would be optimal for guiding beta-lactam dosing, but is often limited by availability. UV/VIS spectrophotometry can quantify drug levels in saline, and if those levels truly reflect plasma concentrations, it could
Low-glycemic index (GI) foods and foods rich in whole grain are associated with reduced risk of type 2 diabetes and cardiovascular disease. We studied the effect of cereal-based bread evening meals (50 g available starch), varying in GI and content of indigestible carbohydrates, on glucose tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At br
Background and Aims: Microscopic colitis [MC] is currently regarded as an inflammatory bowel disease that manifests as two subtypes: collagenous colitis [CC] and lymphocytic colitis [LC]. Whether these represent a clinical continuum or distinct entities is, however, an open question. Genetic investigations may contribute important insight into their respective pathophysiologies. Methods: We conduc
Så kan man använda militära strategier mot cancer – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Så kan man använda militära strategier mot cancer 2017-02-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Kan militära strategier använda
https://www.vetenskaphalsa.se/sa-kan-man-anvanda-militara-strategier-mot-cancer/ - 2026-07-03
OBJECTIVE: To estimate the prevalence and predictors of sustained remission (SR) in patients with psoriatic arthritis (PsA) receiving biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in Sweden. METHODS: All patients with PsA initiating b/tsDMARDs and who were registered in the national Swedish Rheumatology Quality Register (SRQ) from April 1999 to December 2019 wer
During the spring semester 2018, an investigation about supplementary cleaning of the waste water at Dow Chemical site in Landskrona was done. Different water-based binders from acrylic monomers are produced by Dow and large amounts of water is used for such processes. The wastewater, that is treated currently by ultrafiltration (UF), contains different chemical residues such as surfactants, resid
Transport in and through biological membranes that consist of lipid bilayers has a crucial role in many applications in the food or pharmaceutical industries. How to deliver an enzyme through the membranes without damaging the enzymatic activity or the "shelf-life" of the enzyme has been of large interest since 1970 [29-30]. In this work, we have shown that a thin lipid sponge phase (L3)
Background: There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed to identify low-risk cancers where RT will not further reduce recurrence rates. Methods: An individual participant data meta-analysis was performed in 623 patien
Background: In the 1960s only 1/3 of children with soft-tissue sarcomas survived, however with improved treatments survival today has reached 70%. Given the previous poor survival and the rarity of soft-tissue sarcomas, the risk of somatic late effects in a large cohort of Nordic soft-tissue sarcoma survivors has not yet been assessed. Methods: In this population-based cohort study we identified 9
Background: Total pancreatectomy has high morbidity and mortality and differences among countries are currently unknown. This study compared the use and postoperative outcomes of total pancreatectomy among 4 Western countries. Methods: Patients who underwent one-stage total pancreatectomy were included from registries in the United States, Germany, the Netherlands, and Sweden (2014–2018). Use of t
Introduction: Using time-limited trials of low-dose, sustained-release morphine to reduce chronic breathlessness to evaluate net effects may generate opioid withdrawal symptoms if medication is ceased. This sub-study of a larger randomized, placebo-controlled, double-blind trial aimed to evaluate if this occurred. Methods: People with modified Medical Research Council breathlessness scores of 3 or
The incidence of Human Papillomavirus positive (HPV+) tonsillar cancer has been sharply rising during the last two decades. Myeloid cells represent an appropriate therapeutic target due to their ability to orchestrate antigen-specific immunity within the tonsil, the availability of viral antigens, and the proximity of the tumor and the underlying lymphoid tissue. However, the interrelationship of
