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Stem cell-based interventions for the prevention and treatment of intraventricular haemorrhage and encephalopathy of prematurity in preterm infants

Background: Germinal matrix-intraventricular haemorrhage (GMH-IVH) and encephalopathy of prematurity (EoP) remain substantial issues in neonatal intensive care units worldwide. Current therapies to prevent or treat these conditions are limited. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, or regenerate injured brain tissue. These preclinical findings have no

High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures : The MrOS Sweden Study

Because several studies have implicated serotonin as a regulator of bone mass, we here explore its potential association on fracture risk and falls, as on bone mineral density (BMD) and muscle strength, in humans. Serum levels of serotonin were analyzed in 950 men (aged 69 to 81 years), participating in the Gothenburg part of the population-based study MrOS Sweden. Men taking selective serotonin r

Associations of self-reported atopic dermatitis with comorbid conditions in adults : a population-based cross-sectional study

Background: The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults. Methods: A cross-sectional survey was sent to a randomly selected population sample of 78,004 adults in Sweden. The questionnaires included measures of self-reported physical and mental health. Binary and multinomial logistic regression w

Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD

BACKGROUND: Patients with chronic kidney disease (CKD) experience high rates of atherosclerotic cardiovascular disease and death that are not fully explained by traditional risk factors. In animal studies, defective cellular cholesterol efflux pathways which are mediated by the ATP binding cassette transporters ABCA1 and ABCG1 are associated with accelerated atherosclerosis. We hypothesized that c

Pharmacological neuroprotection in severe traumatic brain injury

The basic pathophysiology of TBI consists of an initial, primary injury including rapid deformation of brain tissue with destruction of brain parenchyma and blood vessels and acute loss of neuronal and glial cells. A key concept in the management of TBI is that not all cell death occurs at the time of primary injury; instead, a cascade of molecular and neurochemical secondary events occur during t

Natural history and surgical outcome of Rathke's cleft cysts—A study from the Swedish Pituitary Registry

Objective: Rathke's cleft cysts are benign, embryological remnants in the pituitary gland. The majority of them are small and asymptomatic but a few may become large, and cause mass effects, pituitary hormone deficiencies and visual impairment. Recommendations for the follow-up of Rathke's cleft cysts vary since data on the natural history are sparse. Patients and Design: Data at diagnosis and at

Stem cell-based interventions for the prevention and treatment of germinal matrix-intraventricular haemorrhage in preterm infants

BACKGROUND: Germinal matrix-intraventricular haemorrhage (GMH-IVH) remains a substantial issue in neonatal intensive care units worldwide. Current therapies to prevent or treat GMH-IVH are limited. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, and/or regenerate injured brain tissue. These preclinical findings have now culminated in ongoing human neonatal stud

Sarcopenia and relationships between muscle mass, measured glomerular filtration rate and physical function in patients with chronic kidney disease stages 3–5.

Background Sarcopenia and poor physical function are common in patients with chronic kidney disease (CKD). Our aim was to investigate the relationships between muscle mass and measured glomerular filtration rate (GFR) and between muscle mass and strength and balance, respectively, in patients with CKD stages 3–5. Methods This is a baseline data analysis of a randomized controlled clinical trial.

Gender, alexithymia and physical inactivity associated with abdominal obesity in type 1 diabetes mellitus: a cross sectional study at a secondary care hospital diabetes clinic

Background Obesity is linked to cardiovascular diseases and increasingly common in type 1 diabetes mellitus (T1DM) since the introduction of intensified insulin therapy. Our main aim was to explore associations between obesity and depression, anxiety, alexithymia and self-image measures and to control for lifestyle variables in a sample of persons with T1DM. Secondary aims were to explore associat

Minimering av avfall i produktion av prefabricerade husmoduler

Leaving a sustainable society for our children is considered an arbitrary goal for the environmental work that is currently taking place in Sweden. Today, 140 million tonnes of non-hazardous waste is generated in Sweden, which is unsustainable. 31% of the non-hazardous waste is traced to the construction industry, the mining industry excluded. Today, the waste is an unused resource that is purchas

Assessment of Urban Sprawl in Mowe/Ibafo Axis of Ogun State using GIS Capabilities

Urban Sprawl is one of the challenges to urban development in many nations. Different aspects of the phenomenon have been researched with a view to providing solutions to myriad of ills attributed to it. For any meaningful intervention, however, assessment of development to ascertain sprawl is essential. Despite this, its quantification and monitoring in environment with paucity of data remains a

Comparing universal kriging and land-use regression for predicting concentrations of gaseous oxides of nitrogen (NOx) for the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air)

Background: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data collected from pollution monitoring sites to predict exposures at subject locations. Land-use regression (LUR) and universal kriging (UK) have been suggested as potential prediction methods. We evalua

Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome

The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, we investigated genetic variation in five 20q13 amplicon genes (MYBL2, AURKA, ZNF217, STK4 and PTPN1) and its impact on breast cancer (BC) susceptibility and clinical outcome. As a novel finding, four polymorphisms in STK4 (rs6017452, rs7271519) and A

Mild hypothermia markedly reduces ischemia related coronary t-PA release.

In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to have proinflammatory properties that could contribute to reperfusion injury. We po

MODIS NDVI satellite data for assessing drought in Somalia during the period 2000-2011

Popular science Using remote sensing to assess drought in Somalia Somalia, the country in East Africa in a region referred to as Horn of Africa is in a civil war, conflict and unrest since 1991. The prolonged conflict increases the impact of droughts in the country which is already prone to drought continuously. The country is frequently exposed to drought, occurring moderately every 3-4 years a

Minimumregeln i praxis - Om Högsta domstolens användning av minimumregeln vid avtalstolkning

När domstolar ska tolka ett avtal och ett tolkningsalternativ inte kan väljas utifrån subjektiv- och objektiv tolkning finns det generella tolkningsregler el-ler prioritetsregler att tillämpa för att fastställa avtalsinnehållet. Huvudsakli-gen finns det två sådana som kan tillämpas, oklarhetsregeln och minimumre-geln. Oklarhetsregeln innebär att avtalet tolkas mot den som bär ansvaret för oklarhetWhen courts fail to choose an appropriate interpretation of a contract based on subjective and objective methods of interpretation, there are general rules of interpretation or priority which can be applied to determine a satisfactory meaning of the contract. Essentially, there are two such rules available. Ac-cording to the contra proferentem rule, the contract or clause is to be inter-preted aga

Hybrid power production for a grid with limited capacity

Med 2024 officiellt uppmätt som det varmaste året hitills är klimatförändringarna och behovet av att minska utsläppen är mer aktuella än någonsin. Sveriges viktigaste uppgift i denna utmaning är att effektivt elektrifiera sina två största källor till koldioxidutsläpp: industrin och transportsektorn. Dessa två sektorer står tillsammans för hela 65 % av landets utsläpp. Elektrifieringen förväntas leThere is an urgent need to reduce CO2 emissions in Sweden, primarily caused by industry and the transport sector, which together accounted for nearly 65% of the country's total CO2 emissions in 2023. A key solution to this challenge is the rapid and effective implementation of green electrification, which involves transitioning industry and transportation to electricity and electricity-based f

Using a GIS to enable an economic, land use and energy output comparison between small wind powered turbines and large-scale wind farms: the case of Oslo, Norway.

Responding to an identified knowledge gap, the study aims to determine if smaller wind turbines located on top of existing urban buildings are more resource efficient (land utilization and economically) than large scale wind farms. To answer this question, using a GIS, the resource efficiency of the Roan wind farm in Northern Norway was compared to a theoretical modeled installation of small-scale

97 01252019 679 097 REVIEW Rewers CurrDiabRpts 2018

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update PATHOGENESIS OF TYPE 1 DIABETES (A PUGLIESE AND SJ RICHARDSON, SECTION EDITORS) The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update Marian Rewers1 & Heikki Hyöty2,3 & Åke Lernmark4 & William Hagopian5 & Jin-Xiong She6 & Desmond Schatz7 & Anette-G Ziegler8 & Jorma Toppari9 & Beena Akolk

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/97%2001252019_679_097_REVIEW_Rewers_CurrDiabRpts_2018.pdf - 2026-05-30

Sidor från Bokomslag_LUkonf2015_beskuret.pdf

Sidor från Bokomslag_LUkonf2015_beskuret.pdf 26 NOVEMBER 2015 Innehållsförteckning Parallella presentationer, kl. 10.40 – 11.10: • C. Aili: Argumentativa kursutvärderingsmodeller – bättre grund för kursutveckling och samtidigt träning i studenternas generiska förmågor? • E. Bjarnason, M. Borg, B. Lindvall: Supervising for Independence – A Case Study of Master Science Projects in Higher Education •

https://www.ahu.lu.se/fileadmin/user_upload/ahu/PDF/Proceedings_Utvecklingskonferens_2015_komp.pdf - 2026-05-28