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Questions about institutional stability and change are critically important for any understanding of political institutions. The field of Historical institutionalism in political science has described, studied and theorized institutions for decades. One of the most recurring concepts utilized in the explanation of institutional stability is path dependence, describing theoretical and empirical mec
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In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c