Filtyp
To better understand the genetics of hearing loss, we performed a genome-wide association meta-analysis with 125,749 cases and 469,497 controls across five cohorts. We identified 53/c loci affecting hearing loss risk, including common coding variants in COL9A3 and TMPRSS3. Through exome sequencing of 108,415 cases and 329,581 controls, we observed rare coding associations with 11 Mendelian hearing
Regulatory B (Breg) cells can dampen inflammation, autoreactivity and transplant rejection. We investigated the frequencies, phenotypes and function of Breg cells in granulomatosis with polyangiitis (GPA) to gain further knowledge to whether there are numerical alterations or limitations of their ability to regulate T-cell function. Frequencies and phenotypes of CD24 hiCD27 + and CD24 hiCD38 hi B-
Multiple myeloma is a heterogeneous hematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2.
Child malnutrition is one of the major health problems in many developing countries and involves many sectors such as health, agriculture and research. Malnutrition in infants usually develops during the introduction of complementary foods, due to a deficit of nutrients, low energy density and the poor bioavailability of vitamins and minerals leading, in turn, to an increase in the risk of disease
BACKGROUND: MicroRNAs (miRNAs) are sought-after biomarkers of complex, polygenic diseases such as type 2 diabetes (T2D). Data-driven biocomputing provides robust and novel avenues for synthesizing evidence from individual miRNA seq studies.OBJECTIVE: To identify miRNA markers associated with T2D, via a data-driven, biocomputing approach on high throughput transcriptomics.MATERIALS AND METHODS: The
https://www.byggmek.lth.se/fileadmin/byggnadskonstruktion/publications/THID/Dimensionering_av_baerverk_i_staal.pdf - 2026-07-11
Beroenden – Sida 6 – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Beroenden Varje steg räknas 2010-05-18 – Vi rör oss ungefär ett maratonlopp mindre i veckan än för 100 år sedan, berättar Maria Bjerstam som är FaR-samordnare inom Region Skåne och sjukgymnast
https://www.vetenskaphalsa.se/kategori/livsstilssjukdomar-och-beroenden/page/6/ - 2026-07-12
Bioenergy – What are the possibilities and trade-offs?In connection to the Clean Energy Week in Malmö and the International Energy Ministerial Meeting in Malmö and Copenhagen, Lund University and Climate-KIC will host a panel discussion with leading researchers and other experts on the topic of bioenergy. The focus will be on the possibilities for transformation into a fossil free society using mo
https://www.climate-kic.lu.se/form/registration-climate-kic-spark-lecture-24-may-2018-1830-2030 - 2026-07-15
This study investigated differences in HPA axis function, measured as salivary cortisol concentrations, between 18 women with chronic trapezius myalgia (MYA) and 30 healthy female controls (CON). In addition, the interactions between HPA axis reactions to psychosocial stress and aspects of pain, health and psychological symptoms were analyzed. Salivary cortisol was measured both in daily life, to
Name of course: Geographical Information Systems for the Social Sciences Course code: SGEG16 Course period: 2015-01-15 to 2015-02-18 (Period 1) 100% Course leader: Ola Hall, Department of Human Geography Email: ola.hall@keg.lu.se Teachers: OH Ola Hall, Department of Human Geography MA Maria Archila Bustos, Department of Human Geography CT System Administrator: LDC Department of Human Geography htt
https://www.keg.lu.se/sites/keg.lu.se/files/schedule_sgeg16_vt2018ver13_12.pdf - 2026-07-16
Den 9 december 1948 antogs konventionen om förebyggande och bestraffning av brottet folkmord. Begreppet “folkmord”, myntat av den framlidne professorn Raphael Lemkin, definieras som den systematiska förintelsen av gruppers grundläggande livsvillkor med syftet att förinta gruppen i sig. I artikel II av folkmordskonventionen definieras folkmord istället som handlingar som “förövas i avsikt att förin
Trauma i barndomen har en betydande inverkan på livslång fysisk och mental hälsa samt utveckling. Tidiga interventioner stärker barnets motståndskraft och mildrar traumans långsiktiga effekter på välbefinnandet. En sådan intervention går ut på att utbilda viktiga vuxna i barnets omgivning för att skapa en gynnsam miljö. Traumamedveten omsorg (TMO) är en intervention som erbjuds som ett utbildningsChildhood trauma significantly impacts lifelong physical and mental health and development. Early interventions enhance child resilience and mitigate trauma's long-term effects on wellbeing. One such intervention is educating adults significant in the child’s life to create a nurturing environment. Trauma-informed Care (TIC, in Swedish “Traumamedveten Omsorg”, TMO) is an intervention offered a
Det straffrättsliga orsaksbegreppet har främst diskuterats i rättsvetenskaplig doktrin, eftersom det saknas en legaldefinition och mängden rättspraxis kring begreppet är begränsad i Sverige. År 2024 kom dock ett avgörande, NJA 2024 s. 36, där Högsta domstolen för första gången uttryckligen diskuterade orsaksbegreppet. Rättsfallet handlade om alternativ kausalitet i form av alternativa dödsorsakThe concept of causation in criminal law has been discussed mainly in legal doctrine, since there is no legal definition, and the amount of case law regard ing the concept is limited, in Sweden. In 2024, a decision was made, NJA 2024 s. 36, where the Swedish Supreme Court explicitly discussed the con cept of causation for the first time. The case was about alternative causality in the terms of
Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more
Introduction: The transition from pediatric to adult healthcare represents a crucial period for adolescents and youth living with HIV. When this healthcare transition is not properly managed, it can result in negative outcomes such as loss to follow-up (LTFU), increased morbidity, and mortality. Therefore, it is essential to estimate the incidence rate and identify predictors of loss to follow-up
Introduction/Background: Measurement of umbilical cord blood gasesat birth is the gold standard of capturing the metabolic state of the newborn. Dual sampling of umbilical cord vessels is mandatory, yet the longterm predictive value of venoarterial differences, ΔpH, remain undetermined. Previously, large ΔpH showed a protective effect against adverseneonatal outcomes.Objectives: To investigate the
Two bypassing agents are currently available to circumvent the need for factor FVIII in hemophilia A patients with inhibitors: the activated prothrombin complex FEIBA VH and recombinant activated factor VII (NovoSeven (R)). Both products are highly effective in controlling bleeding in the presence of inhibitory alloantibodies, yet their hemostatic efficacy can be unpredictable. As the results of t
