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Conclusions. The presented analysis of nasal polyposis using connectivity based on the PubGene literature co-citation network demonstrates that this tool can be used to identify key genes in DNA microarray studies of human polygenic diseases. Objectives. DNA microarray studies of complex diseases may reveal differential expression of hundreds of genes. According to network theory and studies of ye

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Ovariectomized virginal rabbits were treated with either estrogen or progesterone for 4 to 6 months. In vitro responses of muscle strips of the bladder and circular urethra were examined. Estrogen resulted in bladder contractions in response to noradrenaline and phenylephrine, whereas these agonists were without effect or evoked weak relaxations in castrated animals (and normals). Estrogen also ca

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Objectives. To study possible nerve regeneration of a damaged auditory nerve by the use of stem cell transplantation. Methods. We transplanted HNPCs to the rat AN trunk by the internal auditory meatus (IAM). Furthermore, we studied if addition of BDNF affects survival and phenotypic differentiation of the grafted HNPCs. A bioactive nanofiber gel (PA gel), in selected groups mixed with BDNF, was ap

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Molybdenum complexes of 3,6-di-tert-butylcatechol have been prepared from the reaction between [Mo(CO)6] and 3,6-di-tert-butyl-1,2-benzoquinone. A putative "[MoO(3,6-DBCat)2]" monomer is assumed to form initially by reaction with trace quantities of oxygen. Condensation of the reaction mixture leads to the formation of oligomeric products, including the [{MoO(3,6-DBCat)2}4] chiral square isolated

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Introduction: The Assessment of Learning Powered mobility use (ALP) tool including the ALP instrument and facilitating strategies, was developed for Driving to Learn. This therapeutic intervention aims to provide children and adults who have profound cognitive disabilities with opportunities to learn tool use through powered mobility practise. To allow for longer intervention periods, a partnershi

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Fake canonizations are prevalent in the former communist countries wherein arts and culture in general may still function as propaganda weaponry at the hands of the sponsoring state. The public is almost eliminated from the process of canonization, as the publishing houses, art galleries, and cultural industries seldom survive and flourish from sales to a real public. As a rule, their rarefied pub

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BACKGROUND: Childhood pre-B acute lymphoblastic leukemia (ALL) is a bone marrow (BM) derived disease, which often disseminates out of the BM cavity, where malignant cells to a variable degree can be found circulating in the peripheral blood (PB). Normal pre-B cells are absolutely dependent on BM stroma for survival and differentiation. It is not known whether transformed pre-B ALL cells retain any

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There is no reference method that is generally acknowledged to be unbiased for the determination of the concentration of any protein in biological fluids. This is probably because mass spectrometry (MS) methods acknowledged as reference methods for determination of low molecular mass substances in biological fluids, e.g. creatinine, have been difficult to adapt for proteins. Here we suggest two te

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Background: Pre-hospital electrocardiogram (ECG) transmission to an expert for interpretation and triage reduces time to acute percutaneous coronary intervention (PCI) in patients with ST elevation Myocardial Infarction (STEMI). In order to detect all STEMI patients, the ECG should be transmitted in all cases of suspected acute cardiac ischemia. The aim of this study was to examine the ability of

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This study aimed to assess the costs and benefits of three alternative second-line treatment strategies for Swedish patients with type 2 diabetes mellitus (T2DM) who fail to reach glycated hemoglobin (HbA1c) ≤ 7% with metformin treatment alone: glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and neutral protamine Hagedorn (NPH) insulin.

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To evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of hepatic function. Patients with advanced solid malignancies, acceptable bone marrow and renal function, and normal or impaired hepatic function, per NCI-ODWG criteria, were eligible. Initially patients received a single oral dose of 30 mg panobinostat for a 1-week pharmaco

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The purpose of the present study was to increase knowledge about social anxiety within a population that previous research has largely ignored even though it has been showed that difficulties often arise in this period, namely adolescence; by looking upon how frequently occurring it is, to see which symptoms are most commonly experienced and to see if and how social anxiety relates to diverse psyc

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FN-stadgans våldsförbud sätter upp ett absolut förbud mot våldsanvändning stater emellan, och endast en situation av självförsvar eller med mandat från säkerhetsrådet kan en stat få rätt att göra undantag från förbudet. Detta till trots finns det många exempel på fall av våldshandlingar som går utanför förbudets ramar, så kallade humanitära interventioner, och man har i dessa situationer hänvisat The UN Charter sets up an absolute prohibition on the use of force between states, and only a situation of self-defense or a mandate from the Security Council can give the right to make exceptions to the ban. Despite this, there are many examples of cases of violence that goes beyond the prohibition framework, so-called humanitarian interventions, and to justify those operations references to inte

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Abstract Title: Experience the Swedish Buffet: Lessons from a Holistic Leader Development Program Seminar Date: May 29th- 30th, 2012 Course: BUSN49 Degree Project Master Level in Managing People, Knowledge & Change Authors: Liga Lagzdina & Kalliopi Christopoulou Advisor: Sverre Spoelstra Department of Business Administration School of Economics and Management Lund University, Sweden

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There is a need for more efficient measures to ensure responsible migration in host countries. Sports are recognised as a key measure to promote integration. This thesis’s purpose is to increase the understanding of the impacts football clubs have on integration for youth girls with foreign backgrounds in Stockholm, Sweden. This is done by exploring social relations’ role in integration and examin

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Climate change has adverse impact on people’s lives and millions are forced away from their habitual residence because of it. Most experts agree that our standard of living is to blame for such environmental consequences. If not stronger measures are introduced; the situation will deteriorate. The purpose of this essay is to explore if existing legal instruments can be used to protect environmenta

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Background and purpose — Traditional surgery forarthritis of the distal radioulnar joint (DRUJ), which typicallyinvolves resecting the ulnar head, is being increasingly challengedby newer techniques, such as prosthetic ulnar headreplacement. The aim of our prospective cohort study was toinvestigate the clinical and patient-reported functional results,up to 2 years postoperatively, among patients w