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We used the nation-wide Swedish Family-Cancer Database to examine the familial risks of histology-specific bone cancers in offspring by parental or sibling probands. Adjusted standardised incidence ratios (SIRs) were used to measure the risk. Among the 1327 offspring bone cancers, only two parent-offspring pairs and one sibling pair were noted with concordant bone cancer but the SIRs were not sign

Although many studies have examined the associations between occupational exposures and kidney cancer, the evidence is not consistent. To examine the risk of occupational exposures on kidney cancer, we carried out a follow-up study on the economically active Swedish population, based on the latest update of the Swedish Family-Cancer Database. We calculated standardized incidence ratios (SIR) and 9

An investigation of the autonomy of the process region at the tip of a crack is carried out. An elastic plastic linearly hardening material is assumed. A cohesive zone model with constant cohesive stress is chosen. The cohesive zone length is observed to decrease with decreasing hardening rates and increasing cohesive stresses. For a cohesive stress larger than about three times the yield stress t

BACKGROUND: Hypercholesterolemic mice lacking factors required for activation of CD4+ T cells are characterized by reduced development of atherosclerosis. Consequently, it has been assumed that atherosclerosis involves loss of tolerance against modified self-antigens generated in response to hypercholesterolemia and that presentation of such antigens on major histocompatibility complex class II (M

AIMS: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients. METHODS AND RESULTS: Five hundred and twenty-eight patients with a definite diagnosis and no history of sustained VAs/SCD at baseline, aged 38.2 ± 15.5 

BACKGROUND: Several therapies are available for psoriasis, including in some countries oral fumaric acid derivatives (FADs). Even if FADs are not available in the Italian market, they can be prescribed and reimbursed by the National Health Service, on request from the treating physician, when considered as a valuable option in selected patient.METHODS: We performed a retrospective analysis of the

Living in a complex and dynamically changing environment requires accurate and timely behavioural responses that allow for adapting to such changes. Well-developed perceptual systems provide a continuous flow of abundant and up-to-date information on the changes in the environment, and, thereby, allow for tailoring behavioural responses accordingly. However, issuing any behavioral response would n

Aims. We have measured and calculated lifetimes of high lying levels in Nb II, and derived absolute transition probabilities by combining the lifetimes with experimental branching fractions. Methods. The lifetimes were measured using time-resolved laser-induced fluorescence in a two-photon and two-step excitation scheme. The branching fractions were measured in intensity calibrated spectra from a

This paper examines how images of unfortunate childhoods are invoked to make sense of psychological problems in adulthood. I use conversation analysis and membership categorization analysis to study a Swedish radio program in which a psychotherapist talks to people about their personal troubles. The findings suggest that, on one hand, the image of an unfortunate childhood was used as an explanator

Understanding land use and land cover (LULC) change through time is an important aspect when attempting to interpret human-environment interactions through time. Palaeoenvironmental techniques have been crucial in bridging this gap by providing information that has been used to estimate climate change, vegetation change, sea level change etc. through time using a variety of proxies. Producing quan

A multi-port element approach, engineered to address practical design challenges of very high frequency (VHF) phased array radar systems, is presented in this communication. A cornerstone of the antenna element design is its simplicity, which counteracts the mobility issues of physically large and unavoidably bulky ground-based VHF radar systems. The multi-port element introduces a third dimension

Proteins differentially interact with each other across cellular states and conditions, but an efficient proteome-wide strategy to monitor them is lacking. We report the application of thermal proximity coaggregation (TPCA) for high-throughput intracellular monitoring of protein complex dynamics. Significant TPCA signatures observed among well-validated protein-protein interactions correlate posit

In this contribution a practical and rational decision-making approach is presented to be applied for common bridges typically managed by public authorities. The authors have developed a model with the intention to be applicable for practical cases for common bridges in the daily work of bride operators responsible for a large number of assets, yet still maintain the principles of more generic fra

As urban systems continue to grow worldwide, urban peripheries increase in number and typologies, which makes their planning a challenge for sustainable development. The aim of this article is to explore approaches and challenges related to the application of sustainable planning to urban peripheries. We reviewed the content of 102 papers related to sustainable planning in urban peripheries by app

Question: How does reproductive timing in annual social insects evolve under intraspecific exploitation competition and in response to a changing environment? The latter includes shifts in resource abundance, mortality, season length, and resource peak timing, factors often associated with climate change. Background: Climate and land use are changing. Evolutionary ecology must learn to predict how