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Emerging knowledge of cartilage metabolism and structure has stimulated efforts to develop new cartilage-monitoring techniques in health and disease. This article gives an overview of cartilage matrix structure, cartilage metabolism, and significant exogenous factor's to show how such knowledge can guide the development of new means to monitor cartilage. Delayed contrast enhanced MRI of cartilage

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Description: It is stated that even though plentiful of studies over the last decades have been concerned with internationalization in/of higher education, it has not been from the perspectives from the teachers and students and their experiences of aspects of internationalization in relation to their educational context (that is, as a student, and as a teacher). To emphasize the quality dimension

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Objectives: This study explores how different combinations of the number of diseases and experienced symptoms are related to life satisfaction in a population of 296 eighty-year-olds in southern Sweden. Methods: Three different models, visualizing different health profiles, in the form of reported number of diseases and number of experienced symptoms in different combinations were created and are

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The purpose of this work is the enhancement of performance by a new design of monolithic heat exchangers under steady-state operating conditions. Heat transfer phenomena and hydrodynamics have been studied and visualized by computational fluid dynamics (CFD). Further, a simple gas distribution system has been analyzed in purpose to find best performance of the exchanger. To achieve this, 3D simula

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We studied the influence of plasmapheresis on the plasma concentrations of proteins (IgG, IgA, beta 2-microglobulin) used for estimation of tumour cell mass in patients with multiple myeloma. Simultaneously, the effects of plasmapheresis on plasma concentrations of proteins (CRP, alpha 1-antitrypsin, haptoglobin) used for the assessment of inflammatory processes were studied. Also, changes in the

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In the present study, we correlated the various lifestyle habits and their associated mutations in cell cycle (P21 and MDM2) and DNA damage repair (MLH1) genes to investigate their role in gastric cancer (GC). Multifactor dimensionality reduction (MDR) analysis revealed the two-factor model of oral snuff and smoked meat as the significant model for GC risk. The interaction analysis between identif

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The Arctic is warming rapidly, especially in winter, which is causing large-scale reductions in snow cover. Snow is one of the main controls on soil thermodynamics, and changes in its thickness and extent affect both permafrost thaw and soil biogeochemistry. Since soil respiration during the cold season potentially offsets carbon uptake during the growing season, it is essential to achieve a reali

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The aim of this community-randomised smoking cessation (SC) trial was to investigate both recruitment and SC-rates in three municipalities offering financial incentives (FIM) to smokers who stop smoking when attending a municipal SC-program and compare these with three municipalities investing in a campaign (CAM) that should encourage smokers to use the SC-program. Furthermore, in a non-randomised

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With Rasmussen’s abstraction hierarchy as starting point, the present article focuses on understanding some of the aspects guiding the development of a simulation exercise (SimEx) from a multi-faceted perspective, based on interviews and post-exercise evaluations conducted with both exercise designers and participants. The results show that, in order to achieve its overarching objective, an exerci

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BACKGROUND: The inability to observe relevant biological processes in vivo significantly restricts human neurodevelopmental research. Advances in appropriate in vitro model systems, including patient-specific human brain organoids and human cortical spheroids (hCSs), offer a pragmatic solution to this issue. In particular, hCSs are an accessible method for generating homogenous organoids of dorsal