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Obesity is linked to various diseases, including insulin resistance, diabetes, and cardiovascular disorders. The idea of inducing white adipose tissue (WAT) to assume characteristics of brown adipose tissue (BAT), and thus gearing it to fat-burning instead of storage, is receiving serious consideration as potential treatment for obesity and related disorders. Phosphodiesterase 3B (PDE3B) links ins
Contrary to what is sometimes assumed, the elderly in the distant past could not always rely on voluntary care. Therefore, some of them had to develop strategies to secure assistance during old age. We focus on towns in the Low Countries, where family ties were weak, and ageing individuals likely had to plan for old age. We show how members of the middling layers of society could use wills and ret
PURPOSE: Epinephrine is used in local anesthetics to induce vasoconstriction and thus reduce bleeding and prolong the anesthetic effect. Finding the optimal delay between the administration of the anesthetic and skin incision to ensure vasoconstriction and minimize bleeding is important and has recently become the subject of debate. This is the first study to assess blood perfusion and oxygen satu
BACKGROUND: Globally, violence disproportionately affects young people, leading to injury, hospitalisation, death, social dysfunction, and poor mental wellbeing. Moreover, it has far-reaching economic consequences for whole nations, due to loss of productivity. Research suggests that attaining a higher level of education promotes factors that insulate youths from poverty and violence.PURPOSE: In t
Abstract: A popular belief is that the process whereby search engines tailor their search results to individual users, so-called personalization, leads to filter bubbles in the sense of ideologically segregated search results that would tend to reinforce the user’s prior view (filter bubble hypothesis). Since filter bubbles are thought to be detrimental to society, there have been calls for furthe
INTRODUCTION: Type 1 diabetes (T1D) is caused by the destruction of pancreatic islet beta cells resulting in total loss of insulin production. Recent studies have suggested that the destruction may be interrelated to plasma lipids.OBJECTIVES: Specific lipids have previously been shown to be decreased in children who develop T1D before four years of age. Disturbances of plasma lipids prior to clini
BACKGROUND: Information on autonomic neurapraxia in female urogenital surgery is scarce, and a model to study it is not available. OBJECTIVE: To develop a model to study the impact of autonomic neurapraxia on bladder function in female rats, as well as to assess the effects of corticosteroid therapy on the recovery of bladder function in this model. DESIGN, SETTING, AND PARTICIPANTS: Female Spra
To assess parents' opinions about their participation in the longitudinal, multicenter study - The Environmental Determinants of Diabetes in the Young (TEDDY) consortium.
In this chapter, the author analyses a new Swedish curriculum for schools that was presented in 2011 and came into effect the same year. Basically the focus in the subject of music is on playing music, creating music, and listening to music. But key citations within the subject of music show a return to some ideas from the beginning of the 20th century regarding nationalism, a Nordic ethnocentric
Background: Vietnam has achieved considerable success in economic development, poverty reduction, and health over a relatively short period of time. However, there is concern that inequalities in health outcomes and intervention coverage are widening. This study explores if inequalities in reproductive, maternal, newborn and child health and nutrition changed over time in Vietnam in 1997-2006, and
OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital
Hur skapar man en en Reggio Emilia skola med en god utemiljö? Vad är en ens Reggio Emilia? Varför är en god utemiljö viktig? Hur fungerar dagens förskolor? Vad är bra och vad behövs förbättras? Det här examensarbetet har väckt många frågor som jag fått många givande svar på genom intervjuer, studiebesök och litteratur. Kunniga pedagoger, förskolechefer, ateljéristas, verksamma arkitekter och Natur
The production of plastics has seen incredible growth in recent years. Accordingly, the release of plastic particles (micro and nano) into the environment is also increasing. Information on environmental, biological concentrations, and the fate of nanoplastic (NP) in aquatic environments are scarce. Most in vitro studies have been investigating the effects of NPs at higher exposure concentrations
