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Antibodies to double-stranded (dsDNA) are associated with systemic lupus erythematosus (SLE) and directly involved in human lupus nephritis. Information about their glomerular target antigens is inconsistent, and whether availability of target antigens, antibody specificity or avidity are nephritogenic parameters, is not determined. In this study, we analyzed renal tissue from anti-dsDNA antibody-
In order to be able to apply performance design procedures with regard to material flammability in building design, a comprehensive and coherent philosophy on material reaction-to-fire must be developed. This paper gives a general discussion on performance-based design and performance-based test methods for material flammability. A number of end-use scenarios and critical conditions are discussed.
Catalysts belonging to the Mo-V-Nb-Te-O system have been prepared with both a slurry method and hydrothermal synthesis and were tested for propane and propylene ammoxidation to acrylonitrile. All samples were characterized with BET, XRD, ICP and XPS. The catalysts were found to consist of three phases, to which activity and selectivity correlations were made. The results indicate that both an orth
The aim of this study was to estimate costs of treating venous leg ulcers in Sweden and the United Kingdom during 1 year and to quantify costs in different health states, The costs of treating four different types of venous leg ulcers were estimated for 52 weeks by a stochastic health economic model, which simulated resource use data obtained from prospectively collected patient data, expert panel
Leukocyte recruitment in the liver includes a two-step procedure in which selectin-dependent leukocyte rolling is a prerequisite for subsequent CD18-dependent leukocyte firm adhesion in postsinusoidal venules. However, the roles of the individual selectins in leukocyte rolling and adhesion, hepatocellular injury, and apoptosis remain elusive. Therefore, we examined the pathophysiological role of P
In order to reduce the total enzyme consumption in high-solids static hydrolysis of nonwashed steam-exploded willow Salix caprea by mixed cellulase of Trichoderma reesei + Aspergillus foetidus, two different approaches were proposed. In the first case, the enzyme activity adsorbed on residual solids after extended hydrolysis was used for hydrolysis of the newly added substrate. The initial mixing
BACKGROUND AND OBJECTIVES: Atherosclerosis is a multifactorial disease, in part characterized by chronic inflammatory changes in the vessel wall and loss of normal physical and biochemical interactions between endothelial cells and smooth muscle cells. Previous studies [Hu J., Cotgreave IA. J Clin Invest; 99: 1-5] have provided molecular links between inflammation and myoendothelial communication
A search for gravitinos produced in e(+/-)p collisions is performed using the H1 detector at HERA. The data were taken at a centre-of-mass energy of 319 GeV and correspond to an integrated luminosity of 64.3 pb(-1) for e(+)p collisions and 13.5 pb(-1) for e(-)p collisions. If R-parity is not conserved, the t-channel exchange of a selectron can produce a neutralino, which, in models where the gravi
This thesis investigates the effect of Objective-1 regional transfers on the per-capita income growth performance of EU NUTS-3 regions during the budgetary period 2000-2006. To be able to distinguish a causal effect and account for possible endogeneity a quasi-experimental regression-discontinuity design is employed. This strategy relies on the arbitrary set 75%-rule for Objective-1 fund eligibili
Space exploration is an area of growing international interest and activity. China is an emerging space power, has become increasingly active in space exploration, and has advocated for further international cooperation in various space activities. To identify opportunities for international cooperation proposed frameworks have used technical and policy parameters to locate suitable partners for s
Vattendrag i Sverige har genom tiderna blivit mycket påverkade av jordbruk och andra mänskliga faktorer. Framförallt vattendragen i Skåne är kraftigt påverkade och har varit det under de senaste 150 åren, sedan jordbruket gjordes mer effektivt. Utdikning och uträtning av våra åar har gett jordbruken mer plats och effektiviserat det. Ökningen av jordbrukets avkastning har lett till att våra vattendStreams in Scania are and have been highly affected by the intense agriculture taking place in their surroundings. It is known how nutrients and suspended solids severely affect species living in the streams as well as in the watercourses in southwestern parts of Scania where the water ends up in the end. Streams in Scania have been regulated in many ways to increase the agricultural payoff and th
Abstract Parkinson’s disease (PD) is characterized by selective loss of dopaminergic neurons and progressive accumulation of intracellular alpha synuclein protein aggregates known as Lewy bodies. Due to pathological links to both sporadic and inherited cases of PD, alpha synuclein (asyn) has become a focal point for study, although the exact mechanisms of its toxicity are not known. In contrast to
This thesis is focusing on the protection of fundamental human rights at work for third country migrant workers in the European Union, a region which attracts more and more migrant workers in recent years. The first Chapter introduces the background briefly, the methodology and the sources on which the research is conducted on and provides the scope and definition of the issues which are under dis
Klimatmönstren världen över förändras och med dessa den globala distributionen och mängden av landbundet kol, dvs vegetationen som bland annat nyttjas som mat och fiber. Också I sig självt en viktig faktor i klimatets utveckling genom dess roll i energi- och vattenkretsloppen. Vetskap om kvantitet och distribution av landbundet kol och hur detta förändras är en viktigt del av arbetet i att förstå The climatic patterns of the world are changing and with them the spatial distribution of global terrestrial carbon; the food and fiber of the world and in itself an important factor in the changing climate. Knowledge of how the terrestrial carbon stock is changing, its distribution and quantity, is important in understanding how the patterns of the world are changing and large scale models using
Georgia is facing social and economic challenges and at the same time there are signs that more pressure is put on the environment and natural resources. Georgian industry is energy- intense and encompassing deregulations have put even more stress on the environment. How to combine economic and social goals with environmental concerns has been a hotbed for disputes in Georgia. A recognized approac
Asylum seekers and refugees are one of the most demonised and marginalised social groups in Europe. Ireland's current agenda for dealing with refugees and asylum seekers is inadequate. The government of Ireland is aware of the inadequacy of response and has proposed to make a number of changes that will improve the standard of living for those who chose to apply for inclusion in Ireland. Howev
RNA interference (RNAi) has recently been discovered in the budding yeast Saccharomyces castellii. As in other organisms, artificial RNAi could be a useful genetic tool in budding yeast, but the method needs first to be established. S. castellii is also a useful model for telomerase studies, and a knockdown of the telomerase catalytic subunit Est2p could be a new way of unrevealing its functions a
Rapporten är en sammanställning av ett kandidatarbete, huvudsakligen utförd som en ”Minor Field Study” i Kumasi, Ghana och i samarbete med WASHCost. WASHCost är ett pågående internationellt forskningsprojekt med holländska IRC som initiativtagare. Genom att använda data, insamlad av forskare från WASHCost i Ghana har jag undersökt vilka kostnadsdrivare som kan användas för att förutsäga kostnadernUsing data gathered by researchers from WASHCost project in Ghana, this thesis examines how cost drivers can be used to predict capital expenditure for construction of piped water systems for small towns in Ghana. The data is collected from 45 small towns and communities in peri-urban areas in the Volta, Ashanti and Northern region. I have used correlation analysis and multiple regression analysis
Som en effekt av den globala strävan som syftar till att motverka klimatförändringar som tillskrivs ökande koldioxidnivåer i atmosfären försöker man hitta okonventionella sätt att minska koldioxidutsläpp. CCS anses vara en metod med stor potential för detta syfte vilket har föranlett en världsomspännande prospektering av platser som kan användas för geologiskt lagring av koldioxid. Detta arbete As a part of a global attempt to mitigate impending climate change owing to increasing atmospheric CO₂levels unconventional methods which may reduce CO₂ emissions are extensively researched. Carbon Capture and Storage,(CCS) is considered to be a promising method for this purpose. As a consequence, worldwide prospection of geological sites in which CO₂ may be stored is currently underway. This th
