Filtyp
Enhancers are central regulators of cell-type-specific gene expression, yet direct functional mapping of active enhancer-promoter interactions in single cells remains technically challenging. DNA adenine methyltransferase (Dam)-based chromatin recording offers a strategy to mark genomic regions proximal to proteins associated with active transcription sites in vivo, including enhancer regions, and
Aortic valve stenosis is a common congenital heart defect among children. In affected patients, the normal tricuspid valve structure is malformed into a bicuspid valve structure due to a fusion at one commissure. A common treatment is transcatheter balloon valvuloplasty, where a balloon is inserted through the aortic valve and inflated to mechanically tear the fused region, restoring a tricuspid s
How can we understand Gällivare municipality as a sacrifice zone through local narratives of green transition? The transition to low-carbon economies in the wake of the European Green Deal drives increased demands for metals and minerals, renewable energy, biomass from forests – intensifying green extractivism. In Gällivare municipality, located in the rural north of Sweden and within the borders
Received Signal Strength Indicator (RSSI) circuits are critical in modern Wi-Fi receivers, playing a key role in power management and protecting the radio frequency (RF) front-end from saturation and potential damage. This thesis presents the design and evaluation of a novel rectifier circuit conceptualized for use in an RSSI system within an industry-standard 22nm CMOS node, specifically targetin
This essay explores the obligation to redeploy as a result of redundancy, conducting a comparative analysis of the redeployment processes in Sweden and Germany. The purpose of the essay is to examine what constitutes a reasonable redeployment in each country and identify differences and similarities in their respective legislation. This is achieved by using the legal dogmatic method, as the study
Cerebral palsy is an umbrella term for a group of neurological disorders, affecting motor function, movement and posture. Contractures, restrictions in the range of motion of joints, are a common problem affecting people living with cerebral palsy. In the present thesis, the effect of having a contracture on one knee, on the hazard for developing a contracture on the other knee, is explored. This
The knee menisci distribute and dampen mechanical loads. Vulnerability to injury and disease of the meniscus is a global issue, particularly concerning osteoarthritis. The connection between the breakdown of meniscal tissue and its mechanical response is not entirely understood. This thesis seeks to contribute to filling this knowledge gap by developing and implementing a digital volume correlatio
Swedish Title: En Ny Era för Ett Nytt Burma: Avkoloniseringens Diskurs och Nationens Strävan i Burma efter Andra Världskriget This study explores the nature of the nationalist discourse in Burma (Myanmar) in the short period of time following World War II but preceding Burma’s declaration of independence on the 4th of January, 1948. Burma, then a British colony in Southeast Asia, had been promised
Insects are the most diverse group of animals, and among the largest contributors to species richness, accounting for around 66% of known species on Earth. Insects are extremely important pollinators, and to understand the timing of pollination, age distribution within time could give important information. Pollinator phenologies advance more rapidly than plant phenologies that can lead to pollina
Fossil-based resources for plastic production is growingly being challenged by renewable material in applications such as wood-plastic composites. One company dedicated to contribute to this transition is Bio Fiber Tech AB (BFT) who have patented a novel treatment of the wood component for improved compatibility with the polymer matrix. This thesis was in collaboration with BFT with the aim to cha
Neurogenesis, the formation of new neurons from neural stem cells, persists throughout life but with a rapid reduction during aging. With such a reduction, decline in cognitive abilities and the occurrence of neurodegenerative diseases are imminent. It is, therefore, important to better understand the role of key factors involved in the reduction of neurogenesis during aging. Microglia, the brain-
This thesis investigates how place can be understood through assemblage theory and what that implies for the understanding of human relation to place. The framework has been widely used outside and within human geography, at a few instances related to place. Exploring place as assemblage is done through a case study of S:t Pauli cemeteries in Malmö. Main methods are walk along interviews and obser
Early erythrocyte transfusion is common in infants born extremely premature. Research has shown that these children are at greater risk of morbidity later in life, and that iatrogenic blood loss from blood sample analysis is one of the contributing factors to the need for transfusions. Acoustophoresis-based plasmapheresis could potentially be used to reduce the loss of endogenous blood components
Serious Games have gained increased attention in sustainability education. I developed a Serious Game that aims to increase sustainability competencies related to water problems among university students. I applied socio-constructivist learning theory to investigate how sustainability competency can be operationalised in learning outcomes and how these can be translated into game elements. Methodo
This thesis studied methods of improving a background model for a data processing pipeline of LiDAR point clouds. For this, two main approaches were evaluated. The first was to implement and compare three different models for detecting ground in a point cloud. These were based on more classical modeling approaches. The second was to use Deep Learning for semantic segmentation of point clouds and t
This paper examines youth engagement within the Global Landscapes Forum, a conference that took place in Paris, December 2015, and its contribution towards moving intergenerational equity forward. Youth are considered one of the main stakeholders when it comes to decision-making in long-term environmental issues as they are part of the current generation that are likely to face the implications of
Research on why we use a specific mode of thinking has long recognised the relevance of mental costs. The definition of this cost, however, has either been too abstract to be measured or focusing on metabolic costs, which currently is expensive and difficult to measure. In this experiment, we used a paradigm that measures the behavioural cost of three modes of thinking (rational reflection, emotio
