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AIMS/HYPOTHESIS: Several studies have suggested that large fat cells are less responsive to insulin than small fat cells. However, in these studies, large fat cells from obese individuals were compared with smaller fat cells from leaner participants, in effect making it impossible to draw conclusions about whether there is a causal relationship between fat cell size and insulin sensitivity. We hyp

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During the last couple of decades, we have witnessed a proliferation of the project as an organizational solution in sectors as diverse as IT, housing, social services, education and culture. Despite a growing interest in the phenomenon, we know surprisingly little of how processes of public sector projectification unfold in practice, especially at local government level. This article uses an inst

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Intermittent fasting may impart metabolic benefits independent of energy balance by initiating fasting-mediated mechanisms. This randomized controlled trial examined 24-hour fasting with 150% energy intake on alternate days for 3 weeks in lean, healthy individuals (0:150; n = 12). Control groups involved a matched degree of energy restriction applied continuously without fasting (75% energy intake

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Compared to the well-known drivers of spatial variability in gross primary productivity (GPP), the relative importance of climatic variables, soil properties and plant traits to the spatial variability in net ecosystem exchange of CO2 between terrestrial ecosystem and atmosphere (NEE) is poorly understood. We used principal component regression to analyze data from 147 eddy flux sites to disentang

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COL1-related overlap disorder is a condition, which is not yet considered as part of the 2017 EDS classification. However, it should be investigated as an alternative diagnosis for any patient with hypermobile EDS. This could allow providing appropriate genetic counseling.

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Modern Arctic Indigenous peoples face many interconnected pressures, not the least of which is anthropogenic climate change, which is emerging as one of the most dramatic drivers of social and economic change in recent memory. In this paper, we investigate whether or not insights into premodern strategies for coping with climate change—and especially the “deeper histories” of traditional ways-of-k

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Background: Semi-natural pastures are unfertilized grasslands with a long history of traditional low-input grazing management. This kind of pastures are recognized for their high species richness. However, as a consequence of modernization of agriculture, many of the semi-natural pastures have been lost during the last century, leading to a serious threat to farmland biodiversity. Semi-natural pas

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Background: Diabetes has been recognized as a risk factor contributing to the incidence and progression of Parkinson’s disease (PD). Although several hypotheses suggest a number of different mechanisms underlying the aggravation of PD caused by diabetes, less attention has been paid to the fact that diabetes and PD share pathological microvascular alterations in the brain. The characteristics of t

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After the financial crisis in 2008, governments became more aware about how multinational enterprises exploited gaps in the architecture of the international tax system in the globalized world to artificially shift profits to places where there was little or no taxation. It is estimated that base erosion and profit shifting cost countries 100-240 billion USD in lost revenue annually which is equal

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Debts among individuals and households in Sweden have increased over the years. Although statistics from the Swedish Enforcement Authority show that the total number of people registered with excessive debts has declined for the third year in a row, the total amount of debt of those individuals and households who are already overindebted on other hand continues to increase. Moreover, debtors regis

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The unnecessary and disproportionate use of pre-trial detention is a global issue that affects developed and developing countries alike. According to World Prison Brief, Cambodia has ranked 12th (among 217 countries) making it become a country with one of the highest percentages of pre-trial detainees: 71.8 percent to be exact. The excessive and unnecessary use of pre-trial detention in the Kingdo

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This study investigates the market reactions to firms’ first publication of sustainability reports. The data of listed companies in the Nordic, the United States, and Chinese stock markets are utilized to examine whether the event leads to abnormal returns in the short term and whether the results are identical across regions. The companies are divided into two groups based on their impact on the

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With as complex phenomenon as homelessness, collaboration is needed to provide multiple services that are necessary.The aim of this study was to analyse how service providers experience collaboration between municipalities and other service providers on the matter of homelessness in Iceland. Qualitative semi-structured interviews were conducted with eight service providers that work with the homel

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Previous research show, people interpret others through their pre-understanding and stereotypical beliefs. Rape crimes are periodically debated in the Swedish media. The debates often elucidate laws incapability to manage the complexity of rape, focusing on the women as the injured party. The purpose of this study is to highlight the Swedish district court’s conceptualization of the defendant in r

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The aim of this study was to investigate how Palestinian refugee women in refugee camps perceive themselves as actors who affect and influence their lives and communities. Research shows it is a topic that is not often discussed or highlighted in today’s discourse about refugees. The material was conducted through semi-structured interviews with eight Palestinian women in a Palestinian refugee cam

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Environmental and forest conservation have long been perceived as a constraint to economic growth and development. With a growing understanding of the benefits from ecosystem services for people, and benefits for conservation when managed by local people, synergies between conservation and development have become more prominent. This research paper analyses this link by looking at ecotourism as a

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Souvenir shopping is inseparably a part of tourist activity. Recently, Indonesia has observed the phenomenon where famous Indonesian celebrities engage in entrepreneurship and open their own cake shops in tourist destination cities. They describe their product as a novel specialty food souvenir. The tourist activity of purchasing and gift-giving celebrity cakes to others is linked to a consumption