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Introduction: Preoperative chemotherapy in early breast cancer increases the rate of breast preservation and provides prognostic information. In the case of residual disease, a change in subtypes may be observed. Sensitive and reproducible biomarkers predicting treatment response early during the treatment course are needed in order to better exploit the potential benefit of an individualized preo

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Nodularia spumigena is a toxic cyanobacteria that blooms in the Baltic Sea every year. In the brackish water of the Baltic Sea, its toxin, nodularin, mainly affects the biota in the surface water due to the natural buoyancy of this species. However, the fate of the toxin is unknown, once the cyanobacteria bloom enters the more saline waters of the Kattegat. In order to investigate this knowledge g

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We present measurements of azimuthal correlations of charged hadron pairs in sNN=200 GeV Au+Au collisions for the trigger and associated particle transverse-momentum ranges of 14GeV/c) correlations is suppressed compared with that of correlations measured in p+p collisions. At the lowest associated particle pT(0.5

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PurposeIt is not known if mammographic breast compression of a primary tumor causes shedding of tumor cells into the circulatory system. Little is known about how the detection of circulating biomarkers such as circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) is affected by breast compression intervention.MethodsCTCs and ctDNA were analyzed in blood samples collected before and afte

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Background: Neuropsychiatric symptoms (NPS) are very common in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia and are associated with various disadvantageous clinical outcomes including a negative impact on quality of life, caregiver burden, and accelerated disease progression. Despite growing evidence of the efficacy of (non)pharmacological interventions to re

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Following the 7.5-Mw earthquake that occurred on 28 September 2018, a series of field surveys were performed to further understand the impacts of the resulting tsunami. Tsunamis initiated by strike-slip earthquakes are rare. Other factors are suspected to have contributed to this unusual tsunami. One of these factors was the subaerial landslides around Palu Bay, which were observed at several loca

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Introduction: Clothing area factor (fcl) is an indicator of the increase in surface area relative to the nude body for calculation of heat loss from the clothed body to the environment. The aim was to calculate and compare the fcl values from two equations by the photographic method.Method: Thirty-five modern western indoor clothing sets (19 male and 16 female) were tested on a thermal manikin Tor

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A key success factor of the Copernicus programme is to ensure the acceptance of services by users. This acceptance and further adoption is based on high quality products that meet the specific information requirements of the user. In the realm of biodiversity monitoring and reporting on conservation status of Natura 2000 habitats, such products must meet different needs of local site manager and n

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Genomic sequencing of avian haemosporidian parasites (Haemosporida) has been challenging due to excessive contamination from host DNA. In this study, we developed a cost-effective protocol to obtain parasite sequences from naturally infected birds, based on targeted sequence capture and next generation sequencing. With the genomic data of Haemoproteus tartakovskyi as a reference, we successfully s

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The Archean Yilgarn Craton in Western Australia hosts at least five generations of Proterozoic mafic dykes, the oldest previously identified dykes belonging to the ca. 2408–2401 Ma Widgiemooltha Supersuite. We report here the first known Archean mafic dyke dated at 2615 ± 6 Ma by the ID-TIMS U-Pb method on baddeleyite and at 2610 ± 25 Ma using in situ SHRIMP U-Pb dating of baddeleyite. Aeromagneti

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OBJECTIVE: To evaluate speech in 5-year-olds with cleft palate with or without cleft lip (CP±L) treated with primary palatal surgery in 1 stage with muscle reconstruction according to Sommerlad at about 12 months of age.DESIGN: Retrospective study.SETTING: Primary care university hospital.PARTICIPANTS: Eight 5-year-olds with cleft soft palate (SP), 22 with cleft soft/hard palate (SHP), 33 with uni

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In the drop volume method the surface of the drop enlarges throughout the process of the interfacial tension decay. This surface expansion has been measured for drops of various sizes and shapes, where the interfacial tension depression was caused by different proteins such as lysozyme, β-lactoglobulin, bovine serum albumin, sodium caseinate, whey protein concentrate and soy protein isolate at dif

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This presentation highlights results from an action research project in a Swedish primary school. The aim of the project is to investigate digitally-based musical settings with young children in need of special support. Various digital-based music instruments were used to facilitate performing, creating and learning music, alone or in small groups. The theoretical background of the project is foun

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Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this an