Filtyp
Background: In a previous cohort study of 4-year-old Danish children, revaccination with the live measles-mumps-rubella vaccine (MMR) was associated with a 16% reduction in the rate of hospitalization lasting two days or longer for non-measles-mumps-rubella infections. Aim: To examine if the introduction of revaccination with MMR at 4 years of age in Denmark (spring 2008) and at 7–9 years of age i
In this paper, a numerical study of flow, reactions and NOx emissions from a biomass boiler is presented. Detailed reaction mechanisms for the decomposition of tar species, combustion of hydrocarbons and formation of NOx are employed by adopting appropriate reaction sets from literature. The proposed mechanism is used to perform CFD simulations of a laboratory-scale biomass boiler, and temperature
Purpose: To evaluate the interday repeatability in the measurement of parameters used for the detection of progression of keratoconus by prediction limits (PL) for single measurements, and the repeatability coefficient (RC) for the mean of replicate measurements. Design: Prospective reliability analysis for cases and control eyes. Methods: Twenty-five eyes in 25 subjects with KC and 25 eyes in 25
This systematic review contributes to the research field of user participation by suggesting a new holistic approach comprising a cyclic process model for long-term participation in the strategic management of urban green spaces, including analysis, design, and implementation phases, each followed by an evaluation. User participation in urban green spaces is encouraged in international conventions
Pharmaceuticals that are not completely metabolized in the human body are excreted in wastewater and may find their way into surface waters, where they can have harmful effects on aquatic fauna and flora. The implementation of ozonation at wastewater treatment plants (WWTPs) can reduce the amount of pharmaceuticals discharged to the environment. Despite the technology readiness level of ozone trea
The natural products pulchrol and pulchral, isolated from the roots of the Mexican plant Bourreria pulchra, have previously been shown to possess an antiparasitic activity toward Trypanosoma cruzi, Leishmania braziliensis and L. amazonensis, protozoa responsible for the Chagas disease and leishmaniasis. These infections have been classified as neglected diseases, and still require the development
Modelling capabilities have drastically improved in the last decade. However, in most of the cases the fire response of building elements is predicted by fitting input material properties to the models in order to match test data. This paper presents models developed to predict the unexposed side temperature of stone wool layered composites with stainless steel or gypsum claddings exposed to sever
In 1876, the Kaitakushi, the Japanese government agency responsible for the settlement of the northern island of Hokkaido, hired three Americans from Massachusetts Agricultural College: William Smith Clark, William Wheeler and David Pearce Penhallow. Their task was to establish a comparable institution in Hokkaido, Sapporo Agricultural College, that would spread American-style scientific agricultu
The efficiency of irrigation, as well as optimization of nutrients, affect spinach yield in all growth stages. In this study, the sensitivity of spinach (early and mature yields) to shallow saline groundwater and the effect of fertigation treatments on mature yield were experimentally investigated. The sprinkler irrigation experiments were conducted on 0.47 ha of silty clay soil at the University
Recent studies indicate a crucial role for neuronal glycogen storage and degradation in memory formation. We have previously identified alpha-amylase (α-amylase), a glycogen degradation enzyme, located within synaptic-like structures in CA1 pyramidal neurons and shown that individuals with a high copy number variation of α-amylase perform better on the episodic memory test. We reported that neuron
Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by a functional haploinsufficiency of genes coding for ribosomal proteins. Among these genes, the ribosomal protein S19 (RPS19) gene is the most frequently mutated. Previously, a mouse model deficient in RPS19 was developed by our laboratory, which recapitulates the hematopoietic disease phenotype by manifesting pathologic f
Fifty-one half-sib families with 2768 sires were selected for this study to confirm a quantitative trait locus (QTL) detected within a previous project initiated by the German Cattle Breeders Federation (ADR). The data based on a granddaughter design were divided into two parts and were analysed using linear models and paternal half sib regression methods. The results strongly support the hypothes
Natural hazards (i.e. earthquakes, floods) become disaster when they strike the man-made environment. To effectively reduce the impact of every disaster, governments prepare a complete strategy, called disaster management. Availability of data such as: buildings, lifeline systems, roads, hospitals and etc, will help the managers to better decision-making. The majority of this data is spatial and c
Biomedical research projects involving multiple partners from public and private sectors require coherent internal governance mechanisms to engender good working relationships. The DIRECT project is an example of such a venture, funded by the Innovative Medicines Initiative Joint Undertaking (IMI JU). This paper describes the data access policy that was developed within DIRECT to support data acce
A search is presented for the direct pair production of the stop, the supersymmetric partner of the top quark, that decays through an R-parity-violating coupling to a final state with two leptons and two jets, at least one of which is identified as a b-jet. The data set corresponds to an integrated luminosity of 36.1 fb-1 of proton-proton collisions at a center-of-mass energy of √s= 13 TeV, collec
RESEARCH DESIGN AND METHODS: We studied participants in PROVALID (PROspective cohort study in patients with type 2 diabetes mellitus for VALIDation of biomarkers), a prospective multinational cohort study of patients with type 2 diabetes and a follow-up of more than 24 months (n = 2,560; baseline median eGFR, 84 mL/min/1.73 m2; urine albumin-to-creatinine ratio, 8.1 mg/g). The 17 biomarkers were m
Background: We have previously shown that podocalyxin-like protein (PODXL) is a prognostic biomarker for poor survival in gastric and esophageal adenocarcinoma treated with surgery up-front. The aim of the present study was to assess PODXL expression in tumors from patients treated with neoadjuvant ± adjuvant (i.e. preoperative with or without postoperative) chemotherapy, with regard to histopatho
The standard therapy for patients with haemophilia is prophylactic treatment with replacement factor VIII (FVIII) or factor IX (FIX). Patients who develop inhibitors against FVIII/FIX face an increased risk of bleeding, and the likelihood of early development of progressive arthropathy, alongside higher treatment-related costs. Bypassing agents can be used to prevent and control bleeding, as well
In this paper we derive the finite-sample distribution of the estimated weights of the tangency portfolio when both the population and the sample covariance matrices are singular. These results are used in the derivation of a statistical test on the weights of the tangency portfolio where the distribution of the test statistic is obtained under both the null and alternative hypotheses. Moreover, w
