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Introduction: The importance of mobile health has increased during recent years but few studies have described the use of apps among persons with neurological disabilities. Aim: The aim of this paper was to describe how persons ageing with a neurological disability experience barriers and facilitators in relation to using apps in everyday life. Method: A qualitative approach was used. 16 persons w
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The conversion of lignin to potentially high-value low molecular weight compounds often results in complex mixtures of monomeric and oligomeric compounds. In this study, a method for the quantitative and qualitative analysis of 40 lignin-derived compounds using ultra-high-performance supercritical fluid chromatography coupled to quadrupole-time-of-flight mass spectrometry (UHPSFC/QTOF-MS) has been
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Background: Breastfeeding rates in Sweden are declining, and it is important to identify women at risk for early cessation of exclusive breastfeeding. Objective: The aim of this study was to investigate factors associated with exclusive breastfeeding lasting less than two months postpartum. Methods: A population-based longitudinal study was conducted at Uppsala University Hospital, Sweden. Six hun
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Geocoding longitudinal and individual-level historical demographic databases enables novel analyses of how micro-level geographic factors affected demographic outcomes over long periods. However, such detailed geocoding involves high costs. Additionally, the high spatial resolution cannot be properly utilized if inappropriate methods are used to quantify the geographic factors. We assess how diffe
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Background: Diabetic foot ulcers are a common and severe complication of diabetes mellitus. Standard treatment includes debridement, offloading, management of infection and revascularisation where appropriate, although healing times may be long. The LeucoPatch® device is used to generate an autologous platelet-rich fibrin and leucocyte wound dressing produced from the patient's own venous blood by
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Aims: This analysis aimed to evaluate the incidence and predictors of the need for permanent pacemaker (PPM) implantation following implantation of the repositionable and fully retrievable LOTUS Aortic Valve Replacement System. Methods and results: The prospective, single-arm, multicentre REPRISE II study with extended cohort enrolled 250 symptomatic, high surgical risk patients with severe aortic
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Monoterpenoid indole alkaloids (MIAs) are produced as plant defence compounds. In the medicinal plant Catharanthus roseus, they comprise the anticancer compounds vinblastine and vincristine. The iridoid (monoterpenoid) pathway forms one of the two branches that feed MIA biosynthesis and its activation is regulated by the transcription factor (TF) basic helix-loop-helix (bHLH) iridoid synthesis 1 (
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Objective: The authors sought to determine whether pregnancy is an intrinsic motivator for cessation of drug abuse. Method: The authors conducted prospective cohort, corelative, co-spouse, and within-person analyses of registration for drug abuse during pregnancy among Swedish women born between 1980 and 1990 who gave birth between ages 20 and 35 (N=149,512). Drug abuse was assessed from medical,
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The Wilms' tumor gene 1 (WT1) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of WT1 associate with a poor prognosis. In mice, WT1 cooperates with the RUNX1/RUNX1T1 (AML1/ETO) fusion gene in the induction of acute leukemia, further emphasizing a role for WT1 in leukemia development. Molecular mechanisms for WT1 are, however, incompletely understood. Here, we identif
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Objective: The primary objective was to evaluate 6-month outcomes for brief and extensive automated telephony interventions targeting problematic alcohol use, in comparison to an assessment-only control group. The secondary objective was to compare levels of problematic alcohol use (hazardous, harmful or probable dependence), gender and age among study participants from clinical psychiatric and ad
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Background: Due to increasing globalization and Internet communication, the number of international marriages has increased. In Sweden, 75% of the Thai population are women, among whom 80% are partnered with Swedish or other Scandinavian men. Previous studies have indicated that lack of autonomy, social isolation, and stigma are important risk factors for poor mental health for foreign-born women
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Buildings today account for 40% of the world’s primary energy use and 24% of the greenhouse gas emissions. Reducing the energy use in buildings is an important measures to reduce energy dependency and greenhouse gas emissions. In Sweden, there are roughly 2 500 000 dwellings in multifamily houses and single family houses. There is a need to address the energy use within the existing dwellings; esp
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The thesis is written within the project Strengthening Legal Education in Vietnam.
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Objective: To examine reliability and validity of the Swedish version of the Self-Efficacy for Rehabilitation (SER) outcome scale. Methods: One-hundred and ninety-eight inpatients (mean age 69 years) who underwent a primary total knee arthroplasty (TKA) due to knee osteoarthritis participated. They responded pre- and postoperatively to the SER outcome scale, and preoperatively to the Hospital Anxi
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OBJECTIVE: According to prevailing consensus, patients with mechanical symptoms are those considered to most likely benefit from arthroscopic surgery. The aim of this study was to determine the value of using patients' pre-operative self-reports of mechanical symptoms as a justification surgery in patients with degenerative meniscus tear/knee disease.DESIGN: Pragmatic prospective cohort of 900 con
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The concrete discs with water-cement ratios 0.4 and 0.7 were preconditioned at their early age by drying at 50`C for 2 to 4 days, followed by storage in a Laboratory atmosphere till an age of 28 or S6 days. The moisture distributions in the specimens were determined by measuring relative humidity and capillary saturation degree, and the air permeability was determined according to the Cembureau me
