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Vulnerable knowledge : Responding to the uncertainties of climate change-related disaster

This paper uses uncertainty generated by environmental change and climate crisis as a prompt to rethink the concept of vulnerability within disaster studies. Where some have sought to recover a latent political potential in vulnerability, a togetherness founded in the disclosure of insecurities to others, we argue that there is value in refusing to settle on any single meaning. This is explored di

G-Quadruplexes in Nuclear Biomolecular Condensates

G-quadruplexes (G4s) have long been implicated in the regulation of chromatin packaging and gene expression. These processes require or are accelerated by the separation of related proteins into liquid condensates on DNA/RNA matrices. While cytoplasmic G4s are acknowledged scaffolds of potentially pathogenic condensates, the possible contribution of G4s to phase transitions in the nucleus has only

Sámi Resurgence through Heritage Work : Exploring Sámi Cosmology in Negotiation with Lutheran Christianity

With the aim to reach deeper insights into dynamics of resilience and resurgence in Sámi systems of knowledge, this article explores how Sámi worldviews and knowledges are enacted and passed on despite violent efforts of erasure by colonial state actors and settler colonialists. I analyze a variety of sources—interviews, a podcast, a documentary and a magazine—to highlight Sámi resilience and resu

Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres

PARP-family ADP-ribosyltransferases (PARPs) and sirtuin deacetylases all use NAD(+) as cosubstrate for ADP-ribosyl transfer. PARP inhibitors are important research tools and several are being evaluated in cancer treatment. With the exception of a few tankyrase inhibitors, all current PARP inhibitors mimic the nicotinamide moiety in NAD(+) and block the nicotinamide binding pocket. We report here t

Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase

Glycosidases are phylogenetically widely distributed enzymes that are crucial for the cleavage of glycosidic bonds. Here, we present the exceptional properties of a putative ancestor of bacterial and eukaryotic family-1 glycosidases. The ancestral protein shares the TIM-barrel fold with its modern descendants but displays large regions with greatly enhanced conformational flexibility. Yet, the bar

Age affects proximal brachial artery stiffness; Differential behavior within the length of the brachial artery?

With increasing age, the diameter of central elastic arteries increases, whereas their distensibility decreases. The purpose of this study was to investigate the mechanical properties of the proximal brachial artery in relation to age and gender. Distensibility coefficient (DC), stiffness and compliance coefficient (CC) were calculated in 136 healthy males and females (range 9-82 y) using echo-tra

Expression of mouse Tbx22 supports its role in palatogenesis and glossogenesis

TBX22 belongs to the T-box family of transcription factors and was originally found in an in silico approach designed to identify new genes on the human Xq12-q21 region. Mutations in TBX22 have been reported in families with X-linked cleft palate and ankyloglossia (CPX), but the underlying pathogenetic mechanism remained unknown. We have identified mouse Tbx22 and analyzed its expression during em

First records of soilborne Phytophthora species in Swedish oak forests

Thirty-two oak stands in southern Sweden, 27 with predominantly declining trees and five with a higher proportion of healthy trees were investigated regarding the presence of soilborne Phytophthora species. Phytophthora quercina , an oak-specific fine root pathogen, was isolated from rhizosphere soil samples in 10 of the 27 declining stands. Additionally, P. cactorum and P. cambivora were recovere

Amerindian ancestry in Argentina is associated with increased risk for systemic lupus erythematosus

Previous studies have demonstrated that in admixed populations, West African ancestry is associated with an increased prevalence of systemic lupus erythematosus (SLE). In the current study, the effect of Amerindian ancestry in SLE was examined in an admixed population in Argentina. The Argentine population is predominantly European with approximately 20% Amerindian admixture, and a very small (<2%

Large scale differentiation and population dynamics in tundra plants and vegetation

The inclusion of the botanical projects in the Swedish-Russian Tundra Ecology -94 expedition provided new information on the ecology of tundra plants. The vegetation patterns on different scales were documented, and interpreted as the result of a complex interaction with environmental factors. The distribution of fruticose lichens was studied, and it was shown that these lichens rely on different

Sara Kalm

Biträdande prefekt forskarutbildning | Studierektor för forskarutbildningen | Docent | Universitetslektor | Meriterad lärare Kontaktinformation E-post: sara [dot] kalm [at] svet [dot] lu [dot] se Telefon: +46 46 222 01 58Organisation Statsvetenskapliga institutionen Rumsnummer: 413 Hämtställe: 31 WebbplatsSara Kalms profil i Lunds universitets forskningsportalAndra roller Biträdande prefekt Statsv

https://www.svet.lu.se/sara-kalm - 2026-06-06

Status of the detector design studies for ESSνSB

The European Spallation Source Neutrino Super Beam (ESSνSB) project aims at a discovery of leptonic CP violation with a precise measurement of the CP phase angle. ESSνSB is characterized by an intense neutrino beam to be produced at ESS by a 5-MW proton beam, and the placement of the far detector at the second oscillation maximum. The aims of the near detector for ESSνSB are neutrino flux and inte

Restoring grasslands in Kenya’s Rift Valley

Grasslands are a prerequisite for rearing livestock, and livestock is the mainstay of people’s existence in drylands. As one Kenyan woman put it, “without grass there is no livestock, without livestock there is no life.” Based in the lowlands of Baringo County in Kenya’s Rift Valley, RAE (Rehabilitating Arid Environments) Ltd. has worked for 38 years to develop a successful socio-ecological model