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Implementering av BCM - En modell för att skapa förutsättningar inom organisationen

Business Continuity Management (BCM) is in many respects a technically oriented field. The technical aspects of BCM are of great importance, however they become meaningless if not used and managed properly. Without adequate human and organizational conditions, there is a risk that BCM does not take the decisive step from solely comprising well-documented business continuity plans, to also generati

Towards brand ecology : An analytical semiotic framework for interpreting the emergence of place brands

Brand-management philosophy has recently expanded to include public and spatial contexts producing a cacophony of logos, slogans and events all aimed at promoting and marketing places. Yet, there is still a lack of understanding about how the brand-management philosophy changes when moving into and across places and in which way places change when affected by this way of thinking. Through a multi-

Resistance to activated protein C due to a factor V gene mutation : The most common inherited risk factor of thrombosis

The protein C anticoagulant pathway is of major importance in maintaining vascular patency. Resistance to the key enzyme of this system, activated protein C (APC), is a recently discovered congenital defect of the protein C system. This genetic defect is present in 20% to 60% of venous thrombosis patients, making it by far the most common known pathogenetic risk factor of thrombosis. APC resistanc

Nerve repair and axonal transport. Distribution of axonally transported proteins during maturation period in regenerating rabbit hypoglossal nerve

The distribution of fast migrating [3H]leucine-labelled proteins was studied in transected and repaired rabbit hypoglossal nerves. The nerves were repaired 90 days earlier with mesothelial chamber or epineurial suture technique. Fast migrating radiolabelled proteins were transported into the distal nerve segment and neurophysiological recordings from the tongue as well as the presence of myelinate

Three in One : Temperature, Solvent and Catalytic Stability by Engineering the Cofactor-Binding Element of Amine Transaminase

Amine transaminase (ATA) catalyse enantioselectively the direct amination of ketones, but insufficient stability during catalysis limits their industrial applicability. Recently, we revealed that ATAs suffer from substrate-induced inactivation mechanism involving dissociation of the enzyme-cofactor intermediate. Here, we report on engineering the cofactor-ring-binding element, which also shapes th

Targeting the reactive intermediate in polysaccharide monooxygenases

Lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism, making them interesting for the production of biofuel from cellulose. However, the details of this activation are unknown; in particular, the nature of the intermediate that attacks the glycoside C–H bond in the polysaccharide is not known, and a nu

Soft X-ray Spectroscopy as a Probe for Gas-Phase Protein Structure : Electron Impact Ionization from Within

Preservation of protein conformation upon transfer into the gas phase is key for structure determination of free single molecules, for example using X-ray free-electron lasers. In the gas phase, the helicity of melittin decreases strongly as the protein's protonation state increases. We demonstrate the sensitivity of soft X-ray spectroscopy to the gas-phase structure of melittin cations ([melittin

Smart Brandbekämpning - Användning av data i strategiskt brandsäkerhetsarbete

Följande rapport är genomförd inom forskningsprojektet Bostadsbränder i storstadsområden - rumsliga skillnader och brandsäkerhetsarbete i den socialt fragmenterade staden. Projektet är finansierat av MSB och har Institutionen för Urbana studier på Malmö universitet och Institutionen för kulturgeografi och ekonomisk geografi vid Lunds universitet som bas. Syftet med denna rapport är att ge en övers

A comparative evaluation of JavaScript execution behavior

JavaScript is a dynamically typed and object-based scripting language with runtime evaluation. It has emerged as an important language for client-side computation of web applications. Previous studies have shown differences in behavior between established JavaScript benchmarks and real-world web applications. However, there still remains several important aspects to explore. In this paper, we comp

Association of brain tumours with other neoplasms in families

We used the nationwide Swedish Family-Cancer Database to analyse the association of histology-specific brain tumours with other cancers in family members. Among 0-68-year-old offspring, 9414 patients with brain tumours were identified from 1961 to 2000, of whom, 3387 parents were diagnosed with any primary neoplasm. Astrocytoma, meningioma and neurinoma were the main histological types. Increased