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Popular Abstract in Swedish Hjärt- och kärlsjukdomar är den största enskilda orsaken till en för tidig död i västvärlden. För att öka kunskapen om dessa sjukdomar är det viktigt att finna mätmetoder, gärna icke-invasiva, som kan användas för att studera tidiga yttringar av hjärt- och kärlsjukdomar. Förändringar av de mekaniska egenskaperna i artärerna kan vara en sådan tidig yttring. För att få etCardiovascular diseases constitute the major cause of morbidity and mortality in the Western World. To increase our knowledge of cardiovascular diseases, it is important to find methods, preferably non-invasive ones, to study very early manifestations of vascular disease. Changes in the mechanical properties of the arteries can be an early manifestation of vascular disease. Further, changes in the
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Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil samples were collected in a vegetable garden accidentally contaminated with elemental mercury 25 years earlier. Bioavailable mercury was measured using different sensors: a protein-based biosensor, a whole bacterial cell based biosensor, and a pl
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An operational definition of vulnerability is proposed. The definition is used to describe and analyse different methods for risk and vulnerability analysis. Several problems related to analysing the vulnerability of a complex sociotechnical system to a specific perturbation are identified and discussed. Suggestions of how risk- and vulnerability analyses can be performed for such systems are pres
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This paper presents a collection of experiences related to success factors in graduate and postgraduate education. The experiences are mainly concerned with how to make the education relevant from an industrial viewpoint. This is emphasized as a key issue in software engineering education and research, as the main objective is to give the students a good basis for large-scale software development
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I allt fler länder börjar en brandteknisk klassificering av byggnadsdelar tillåtas som bygger på en analytisk behandlning i stället för på resultat av ugnprovningar enligt ISO834. I Sverige godtas sedan lång tid en analytisk brandteknisk dimensionering av bärande och avskiljande konstruktioner som ett alternativ till standardiserad termisk påverkan enligt ISO 834. En väsentlig förutsättning för en
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Latin hypercube sampling is suggested as a tool to improve the efficiency of different importance sampling methods for structural reliability analysis. In simple importance sampling, where the sampling centre is moved from the origin to the design point, standard Monte Carlo sampling can be replaced by Latin hypercube sampling. The efficiency improvement is then highly dependent on the choice of s
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By a mixture density is meant a density of the form pi(mu) (.) = f pi(theta) (.) x mu(d theta), where (pi(theta))(theta Theta is an element of) is a family of probability densities and mu is a probability measure on Theta. We consider the problem of identifying the unknown part of this model, the mixing distribution A, from a finite sample of independent observations from pi(mu). Assuming that the
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The stopping powers in silicon of heavy ions, with atomic numbers ranging from 4 to 29, have been determined using a time-of-flight elastic recoil detection analysis (TOF ERDA) set-up. In transmission geometry, the energy loss of heavy elastic recoils in the self-supporting silicon foil of known thickness is measured over a continuous range of recoil energies using time-of-flight (TOF) spectrometr
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OBJECTIVE. To evaluate the recurrence of foot ulcers as well as the cumulative amputation and mortality rates in diabetic patients with previous foot ulcers. DESIGN. A prospective study of consecutively presenting diabetic patients admitted to the Department of Internal Medicine because of foot ulcer with a median follow-up of 4 years. SETTING. A multidisciplinary foot-care team. POPULATION. Five-
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The spectral properties of financial correlation matrices can show features known from completely random matrices. A major reason is noise originating from the finite lengths of the financial time series used to compute the correlation matrix elements. In recent years, various methods have been proposed to reduce this noise, i.e. to clean the correlation matrices. This is of direct practical relev
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OBJECTIVES: Our goal in this study was to explore the use of a hybrid approach to calculate benchmark doses (BMDs) and their 95% lower confidence bounds (BMDLs) for renal effects of cadmium in a population with low environmental exposure. METHODS: Morning urine and blood samples were collected from 820 Swedish women 53-64 years of age. We measured urinary cadmium (U-Cd) and tubular effect markers
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[1] Pathfinder AVHRR NDVI data have been analyzed for the African Sahel to study recent trends in vegetation greenness. A strong increase in seasonal NDVI was observed over large areas in the Sahel during the period 1982-1999. The increase is interpreted as a vegetation recovery from the drought periods of the 1980's. Although strong shifts in satellite overpass times have led to shifting solar ze
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A search for the single production of doubly-charged Higgs bosons H-+/-+/- in ep collisions is presented. The signal is searched for via the Higgs decays into a high mass pair of same charge leptons, one of them being an electron. The analysis uses up to 118 pb(-1) of ep data collected by the H1 experiment at HERA. No evidence for doubly-charged Higgs production is observed and mass dependent uppe
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The introduction of pentose utilization pathways in baker's yeast Saccharomyces cerevisiae is summarized together with metabolic engineering strategies to improve ethanolic pentose fermentation. Bacterial and fungal xylose and arabinose pathways have been expressed in S. cerevisiae but do not generally convey significant ethanolic fermentation traits to this yeast. A large number of rational metab
