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The development of integrated pest management is hampered by lack of information on how insect pest abundances relate to yield losses, and how pests are affected by control measures. In this study, we develop integrated pest management tactics for Apion spp. weevils (Coleoptera: Brentidae) in seed production of red clover, Trifolium pratense L. We tested a method to forecast pest damage, quantifie
BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor
Objective: Degenerative orthopedic diseases (DODs) such as osteoporosis, osteoarthritis, spondylosis, spinal stenosis, and disc herniation are common disorders. Both common and rare genetic risk factors may contribute to DODs, but few large-scale whole-exome sequencing studies elucidating the contribution of rare variations to DODs have been published. The updated version of the Astra Zeneca porta
PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr
Despite the success of antiretroviral therapy, a subset of people with HIV experience low-level viraemia (LLV), a challenging condition with inconsistent definitions and management across settings. We conducted a scoping review of the literature and developed international consensus recommendations through a modified Delphi process involving a multidisciplinary panel of experts. Available evidence
Purpose Children living with respiratory support rely on medical technology, either fully or partially, throughout the day to meet their breathing requirements. Although children and young people living with respiratory support at home undergo long-term treatments and make extensive use of health and social care services, there is a notable absence of comprehensive outcome data on this group. The
The purpose of this project was to find estimates of the operational releases of 14C and 3H from new SMR technology that is being considered in Sweden, namely the Rolls-Royce SMR and the GE-Hitachi BWRX-300. To achieve this goal, models of the reactors of interest were made in the continuous-energy Monte-Carlo neutron and photon transport code Serpent, where the production of 14C and 3H could then
The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological de
Introduction: Inflammatory diseases have been associated with increased risk of venous thromboembolism (VTE). However, data on VTE is lacking in large population-based cohorts of microscopic colitis (MC). Methods: This study included all Swedish adults with incident MC without prior VTE (1990-2017; n=12,489; follow-up until 2021). MC and subtypes (collagenous colitis and lymphocytic colitis) were
Registry-based randomised controlled trials (R-RCTs) represent a paradigm shift in research, with the potential to accomplish pragmatic but large trials with high external validity. In this paper, we review our experiences from planning and performing the REgistry-based randomised controlled trial of treatment Duration and mortality in long-term OXygen therapy (REDOX) trial, the first R-RCT within
INTRODUCTION: Epidemiological studies focusing on the association of exposure to perfluoroalkyl substances (PFAS) with cardiovascular disease (CVD) morbidity and mortality are limited, with inconsistent findings.OBJECTIVES: This register-based study aimed to investigate the associations between exposure to PFAS and the risk of CVD morbidity and mortality in a Swedish population exposed to PFAS, do
Background: Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with lower bone mineral content (BMC) and density (BMD) in children, but prospective studies remain limited. We aimed to investigate associations between prenatal and childhood PFAS exposure and BMC/BMD at age 9 years, following up on our previous findings from age 7 years. Methods: We used data from the Odense
Background: The continuum of care (CoC) for maternal health, which includes ≥4 antenatal care (ANC) visits, delivery assisted by skilled birth attendants, and a postnatal care (PNC) visit within 48 hours of delivery, is a crucial health care package associated with survival and improved health outcomes for children and mothers. In addition, the CoC serves as a platform for delivering messages and
BACKGROUND: Children, adolescents, and young adults with cancer (referred to as CAYAs) are at risk of long-term health complications, with cardiovascular disease (CVD) being a major concern. In addition, sociodemographic characteristics and traditional cardiovascular risk factors may also contribute to disparities in outcomes compared with those of the general population. The aim of this study was
Background and aims: Targeted omics techniques can be used to identify systemic blood biomarkers associated with coronary artery disease (CAD) and cardiovascular disease (CVD) events. Our aim was to study associations between plasma protein, metabolite biomarkers and subclinical CAD in a low and a high CVD risk population. Methods: The Swedish CArdioPulmonary bioImage Study (SCAPIS) was used for i
