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Att aktieägare skriver aktieägaravtal är vanligt förekommande i svenska aktiebolag och då framförallt i mindre, privata bolag. I aktieägaravtalet kan man avtala om bland annat rösträttsbegränsningar och ägarförhållanden. Den allmänna uppfattningen i Sverige har sedan länge varit att aktieägaravtal endast är obligationsrättsliga mellan avtalsparterna, och därmed aldrig kan binda aktiebolaget. Ett a
Different aspects of hybrid control systems are treated: analysis, simulation, design and implementation. A systematic methodology using extended Lyapunov theory for design of hybrid systems is developed. The methodology is based on conventional control designs in separate regions together with a switching strategy. Dynamics are not well defined if the control design methods lead to fast mode sw
Denna studie syftade till att evaluera och undersöka eventuell förändring i psykologisk symtomnivå samt klienttillfredsställelse hos klienter som behandlats med kognitiv beteendeterapi eller psykodynamisk terapi på en utbildningsmottagning för blivande psykologer. Studien syftade även till att undersöka eventuella skillnader i resultatet mellan klienter i kognitiv beteendeterapi och psykodynamisk This study aimed to investigate and evaluate change in psychological symptom levels and client satisfaction in clients treated with cognitive behavioral therapy or psychodynamic psychotherapy at a training clinic for prospective psychologists. The study also aimed to examine possible differences in outcome between clients in cognitive-behavioral therapy and psychodynamic therapy, and to examine wh
Problemformulering: Byggprocessen är idag långsam, kostsam och genererar stora mängder spill och utsläpp. För att kunna möta bostadsbehovet från den snabbt växande befolkningsmängden måste tekniken utvecklas, den måste bli snabbare och mer kostnadseffektiv. Med ny teknik där betongelement tillverkas genom automatiserad och datorstyrd 3D-printning kan eventuellt hela betongbyggnadsprocessen effektiQuestion formulation: The construction process today is slow, costly and generates large amounts of waste and emissions. In order to meet housing needs of the rapidly growing population in a sustainable way, the technology must evolve; it must be faster and more cost-effective. New technology, where concrete is manufactured by automated and computer-controlled 3D-printing, can possibly streamline
AimOur aim is to provide a-priori information on air-quality implications of potential future energy carriers in transportation relevant for sustainability, life cycle and health-impact assessments.MethodologyInformation on air- and climate-pollutant formation from energy carriers is collected in detailed laboratory assessments on heavy-duty combustion engines as well as on non-tailpipe emissions.
Dying in older persons precedes often by a prolonged period of frailty and multimorbidity. The global increase in the aged population means more death at an older age and highlights the need to integrate palliative care in elderly care. Knowledge-based palliative care is lacking outside the specialist units, for which reason there is insufficient access to palliative care for older persons. Thus t
BACKGROUND: First-in-human studies to test the efficacy and safety of human embryonic stem cells (hESC)-derived dopaminergic cells in the treatment of Parkinson's disease (PD) are imminent. Pre-clinical studies using hESC-derived dopamine neuron transplants in rat models have indicated that the benefits parallel those shown with fetal tissue but have thus far failed to consider how ongoing L-DOPA
Introduction: Housing shortage due to population growth within metropolitan areas, combined with an ageing population, has put pressure on current housing provision in Sweden. Thus, there is an urgent need to develop sustainable housing policies to accommodate the growing number of seniors in accessible home environments. This study aimed to gain an in-depth understanding of how municipalities cur
Global value chains (‘GVCs’) have become a basic operative unit of economic production. Their development over the twentieth and twenty-first centuries has resulted in immense creation of wealth while linking together individuals, companies and economies across the world. But GVCs are also a major cause for environmental degradation, carbon emissions and human rights abuses—the ‘externalities’ of
Stem cell therapies for Parkinson’s disease (PD) have entered first-in-human clinical trials using a set of technically related methods to produce mesencephalic dopamine (mDA) neurons from human pluripotent stem cells (hPSCs). Here, we outline an approach for high-yield derivation of mDA neurons that principally differs from alternative technologies by utilizing retinoic acid (RA) signaling, inste
Dolutegravir-based antiretroviral therapy (ART) has been scaled up in many developing countries, including Ethiopia. However, subtype-dependent polymorphic differences might influence the occurrence of HIV-drug-resistance mutations (HIVDRMs). We analyzed the prevalence of pre-treatment integrase strand transfer inhibitor (INSTI) HIVDRMs and naturally occurring polymorphisms (NOPs) of the integrase
Precipitation is intrinsically associated with high uncertainty, which is exacerbated exponentially over time—especially concerning climate change. However, the current design practice in urban drainage infrastructure remains firmly bound to deterministic assumptions regarding the design load. This approach is too simplified—focusing only on the return period of the design event—and ignores the co
BackgroundLow concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis. Recently, natural autoantibodies (aAb) with antagonistic properties to SELENOP uptake have been identified in healthy subjects, and in patients with thyroid disease. Given the potential transport disrupting properties, we hyp
The unfolding COVID-19 pandemic, and the unprecedented social and economic costs it has inflicted, provide an important opportunity to scrutinize the interplay between the resilience of small and medium-sized enterprises (SMEs) and the resilience of the communities they are embedded in. In this article, we articulate the specific ways that SMEs play a crucial, and underappreciated role in building
BackgroundThe knowledge about striatal hand deformities (SHD) in Parkinson’s disease (PD), has recently increased but need more attention due to their early impact on dexterity. The focus of clinical studies has been on the staging of SHD severity and neurological features. However, a hand surgical perspective has not been considered.ObjectivesOur purpose was to examine SHD in patients with PD usi
To clarify the role of differential diffusion in highly turbulent premixed flames, a series of turbulent premixed ammonia/hydrogen/air flames were investigated using the NH-PLIF diagnostics. The investigated flames have almost the same laminar burning velocity, SL, but are characterized by different Lewis number, Le, from 0.56 to 1.77. The Karlovitz number, Ka, of these flames ranges from 11 to 10
BackgroundCarotid artery disease is highly prevalent and a main cause of ischemic stroke and vascular dementia. There is a paucity of information on predictors of serious vascular events. Besides percentage diameter stenosis, international guidelines also recommend the evaluation of qualitative characteristics of carotid artery disease as a guide to treatment, but with no agreement on which qualit
HIV-2 is less pathogenic compared to HIV-1. Still, disease progression may develop in aviremic HIV-2 infection, but the driving forces and mechanisms behind such development are unclear. Here, we aimed to reveal the immunophenotypic pattern associated with CD8 T-cell pathology in HIV-2 infection, in relation to viremia and markers of disease progression. The relationships between pathological diff
