Filtyp
Electron paramagnetic resonance of Cr3+ ions in β -Ga2O3 is investigated using terahertz spectroscopic ellipsometry under magnetic field sweeping, a technique that enables the polarization resolving capabilities of ellipsometry for magnetic resonance measurements. We employed a single-crystal chromium-doped β -Ga2O3 sample, grown by the Czochralski method, and performed ellipsometry measurements a
X-ray fluorescence emission spectroscopy is a powerful tool to gain chemical information on a wide variety of samples. Its combination with focused X-ray beams and translation stages enables X-ray fluorescence microscopy, generating quantitative distribution maps for sets of chemical elements, depending on incident photon energy and detector specifications. The use of synchrotron radiation for X-r
We present an operando study where Ambient-Pressure X-ray Photoelectron Spectroscopy (AP-XPS), Polarization Modulation-InfraRed Reflection Absorption Spectroscopy (PM-IRRAS) and Mass Spectrometry (MS) were employed simultaneously with sub-minute time resolution to monitor the CO oxidation and NO reduction reactions on Rh(111). AP-XPS is a powerful tool to follow reactions at the surface-gas interf
OBJECTIVE: To explore the associations between daily time in sedentary behaviour (SED) and physical activity (PA) with perceived physical capacity, health-related quality of life (HRQoL) and fatigue in persons with post COVID-19 condition (PCC). An additional objective was to describe changes in SED and PA levels over three months.MATERIALS AND METHODS: Individuals with PCC self-reported on physic
LTx remains the definitive treatment for end-stage lung disease, but the increasing demand for donor lungs outpaces the available supply. This chapter explores innovative approaches to expand the pool of viable donor lungs and reduce waiting times, which is crucial to lowering mortality rates among patients on transplant lists. Xenotransplantation, which has made its greatest strides using porcine
As advancements in transplantation techniques continue, the challenge remains the limited availability of suitable donor organs. This chapter explores strategies to expand the donor pool and optimise transplant outcomes, which include the use of extended criteria donors, living lobar transplantation, donor-to-recipient graft size matching, and innovations in hypothermic storage and ex vivo lung pe
Supported lipid bilayers (SLBs), formed via lipid vesicle adsorption on highly curved silica surfaces, are widely used in biosensor applications and as models for curved cell membranes. However, SLB formation is often hindered on convex structures with radii comparable to the vesicles. In this study, lightguiding semiconductor nanowires (NWs), engineered for fluorescence signal enhancement, were u
Extracellular vesicles (EVs) carry biological information from their parent cell to other cells in the body. To intercept and decipher this information necessitates the isolation of EVs from complex backgrounds such as blood or spinal fluid. Acoustic trapping has been previously demonstrated as a promising technique for EV isolation from cell media, blood plasma and urine. The acoustic fields stru
Objective: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides are heterogeneous disorders. The aim of this study was to identify and characterize subgroups of patients based on sex, ANCA, age at diagnosis, and organ involvement. Methods: In total, 1,167 patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) were retrospectively recruited to the s
Catalytic studies traditionally rely on steady-state conditions resulting in time-averaged datasets that do not differentiate between active and spectator species. This limitation can cause misinterpretations of catalytic function, as the signal of short-lived intermediates responsible for producing desired reaction products is often masked by more intense spectator species. Time-resolved ambient
Background: Hexavalent chromium (Cr(VI)) is a lung cancer carcinogen. However, the genotoxic and mutagenic effects of Cr(VI) in humans at low-to-moderate occupational exposure levels are unknown. This study aims to investigate the relationship between occupational exposure to Cr(VI) and the presence of oxidative damage, genetic and epigenetic alterations. Methods: We included 113 Cr(VI) exposed wo
Non-polar and semi-polar III-nitrides have beneficial properties for various electronic applications such as light emitting diodes and photodetectors due to the elimination or reduction of polarization effects. However, cost-effective manufacturing of non-polar and semi-polar III-nitride films with sufficient film quality is not feasible yet. We report an investigation of the morphological and str
High-speed vertical III–V nanowire transistors utilize their channel material for high frequency and low noise performance. A device layout revision to optimize gate resistance, in a trade-off to gate-source capacitance, is presented. A two-step redesign of the established device layout is proposed. First step is demonstrated with fabricated structures. The second step predicts the design transiti
The development of sustainable photosensitiser complexes based on Earth-abundant metallic elements is important for sustainable solar energy conversion and green synthesis through photocatalysis. We report the synthesis and characterisation of a new bis(tripodal) iron(III) N-heterocyclic carbene complex [Fe(PhB{impy}3)2]+ (PhB{impy}3 = phenyltris(imidazo-[1,5-a]-pyridinylidene)borate) featuring -e
Chaperones may retard the aggregation of other proteins and increase their solubility. An important goal is a thermodynamic understanding of such an action. Here, the chaperone DNAJB6b (JB6) is found to suppress amyloid formation of the protein α-synuclein (α-syn) leading to a reduced rate of fibril formation and an increase in apparent solubility of α-syn. These findings were reached at mildly ac
Background: Understanding the relationship between serum ferritin levels and cardiovascular outcomes in type 2 diabetes is crucial for improving risk stratification and guiding therapeutic interventions aimed at preventing major adverse cardiovascular events (MACE). This study aimed to identify distinct clusters of individuals with type 2 diabetes who have varying risks of MACE using a data-driven
We compared vaccine effectiveness against severe COVID-19 between December 2021 and March 2022 when Omicron BA.1 and BA.2 were the dominating SARS-CoV-2 variants in Scania county, Sweden. Effectiveness remained above 80% after the transition from BA.1 to BA.2 among people with at least three vaccine doses but the point estimate decreased markedly to 54% among those with only two doses. Protection
Background: Obesity seems to be associated with a poorer response to adjuvant chemotherapy in breast cancer (BC); however, associations in the neoadjuvant chemotherapy (NACT) setting and according to menopausal status are less studied. This study aims to investigate the association between pretreatment body mass index (BMI) and pathological complete response (pCR) following NACT in BC according to
