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Analysis of the case studies of two preschool children with profound cognitive disabilities indicates that training in a powered wheelchair can increase wakefulness and alertness, stimulate a limited use of the arms and hands, and promote the understanding of very simple cause-and-effect relationships. The enhanced activity level had a positive influence on the children's ability to react to exter
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Extreme values of non-linear functions of multivariate Gaussian processes are of considerable interest in engineering sciences dealing with the safety of structures. One then seeks the survival probability P{(X1(t),⋯ ,Xn(t))∈ S, all t∈ [0,T]}, where X(t)=(X1(t),⋯ ,Xn(t)) is a stationary, multivariate Gaussian load process, and S is a safe region. In general, the asymptotic survival probability for
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Popular Abstract in Swedish Blodåderförkalkning och dess komplikationer såsom hjärn- och hjärtinfarkt är bland de vanligaste orsakerna till sjukdom och död i vårt samhälle. Flera faktorer är av betydelse för uppkomsten av åderförkalkning. I denna avhandling presenteras studier av substanser frisatta från kärlendothelet (blodkärlväggarnas insida) respektive från vita blodkroppar, och dessa substansThis study was undertaken to evaluate relationships between endothelial function (assessed as mediators of endothelium-derived vasoactive factors such as nitric oxide [NO], prostacyclin [PGI2] and endothelin [ET-1] ), and risk factors for atherosclerosis, as well as to study possible relationships between endothelial function and leukocyte activation (indicated by measurements of leukocyte-derived
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Purpose: To quantify fixation stability in patients with neovascular age-related macular degeneration (nAMD) at baseline, 3 and 6 months after anti-vascular endothelial growth factor (anti-VEGF) treatment and furthermore asses the implications of an unsteady fixation for multifocal electroretinography (mfERG) measurements. Methods: Fifty eyes of 50 nAMD patients receiving intravitreal anti-VEGF tr
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The performance of single-channel temporal noise reduction methods generally deteriorate in high noise environments, whereas spatial beamformers can maintain some level of speech enhancement. This paper presents a solution where a low complexity single-channel noise reduction method is integrated into the feedback control loop of an adaptive blind beamformer with the purpose of robust blind speech
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Existing criteria recommended by ACC/ESC for identifying patients with ST-elevation myocardial infarction (STEMI) from the 12-lead ECG perform with high specificity (SP), but low sensitivity (SE). In our previous study, we found that the SE of acute ischemia detection can be markedly improved without any loss of SP by calculating, from the 12-lead ECG, ST elevation in 3 vessel-specific leads (VSLs
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Despite increasing access to antiretroviral treatment (ART) in low-income countries, HIV-related mortality is high, especially in the first months following ART initiation. We aimed to evaluate the impact of TB coinfection on early mortality and to assess gender-specific predictors of mortality in a cohort of Ethiopian adults subjected to intensified casefinding for active TB before starting ART.
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The MAX IV facility includes two storage rings operated at 1.5 GeV and 3 GeV. Both rings make use of a 100 MHz RF system and are designed to operate with a uniform multibunch fill pattern aswell as employ passive harmonic cavities to damp instabilities and increase Touschek lifetime. Recently, a discussion on timing modes at the MAX IV storage rings has been initiated by the user community. This i
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Background: Sierra Leone is a low income country in West Africa that has a history of conflict. Sierra Leone have signed and ratified the Convention of Rights of Persons with Disabilities.Aim: To evaluate persons with disability that use prosthetic and orthotic assistive devices access to human rights. The addressed areas were; right to health, right to a standard of living adequate for health, ri
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Bovine α-lactalbumin (BLA) forms cytotoxic complexes with oleic acid (OA) that perturbs tumor cell membranes, but molecular determinants of these membrane-interactions remain poorly understood. Here, we aim to obtain molecular insights into the interaction of BLA/BLA-OA complex with model membranes. We characterized the folding state of BLA-OA complex using tryptophan fluorescence and resolved res
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We present a digital-to-time converter (DTC)-assisted fractional-N wide-bandwidth all-digital PLL (ADPLL). It employs a MASH ΔΣ time-to-digital converter (TDC) to achieve low in-band phase noise, and a wide-tuning range digitally-controlled oscillator (DCO). Fabricated in 40nm CMOS, the ADPLL consumes 10.7 mW while outputting 1.73 to 3.38 GHz (after a ÷2 division) and achieves better than -109 dBc
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The paper analyses some properties that are obtained when using load current measurements to control DC-DC power converters. The analysis is made for the buck, boost, and buck-boost converters with current mode control. The two major properties obtained are low output impedance and an almost invariant control-to-output transfer function for different loads. It is shown that the use of the load cur
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Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtain
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Synthetic molecular motors typically take nanometer-scale steps through rectification of thermal motion. Here we propose Inchworm, a DNA-based motor that employs a pronounced power stroke to take micrometer-scale steps on a time scale of seconds, and we design, fabricate, and analyze the nanofluidic device needed to operate the motor. Inchworm is a kbp-long, double-stranded DNA confined inside a n
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A search for pair-produced third generation scalar leptoquarks is presented, using proton-proton collisions at root s = 7 TeV at the LHC. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 4.7 fb(-1). Each leptoquark is assumed to decay to a tau lepton and a b-quark with a branching fraction equal to 100%. No statistically significant excess above the Stan
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This study is motivated by the need to know the characteristics of the learning processes in tongue-computer interaction and to obtain a useful insight to a better design of the tongue-computer interface for computer text input. Tongue-typing can be a good alternative to hand input methods for physically disabled individuals or tasks where hand-typing is not possible. In order to evaluate the proc
